Zobrazeno 1 - 10
of 580
pro vyhledávání: '"Yoshihiro Urade"'
Autor:
Namiko Nishida, Nanae Nagata, Keigo Shimoji, Naoto Jingami, Kengo Uemura, Akihiko Ozaki, Makio Takahashi, Yoshihiro Urade, Sadayuki Matsumoto, Koichi Iwasaki, Ryosuke Okumura, Masatsune Ishikawa, Hiroki Toda
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
Idiopathic normal pressure hydrocephalus in elderly people is considered a form of glymphopathy caused by malfunction of the waste clearance pathway, called the glymphatic system. Tau is a representative waste material similar to amyloid-β. During n
Externí odkaz:
https://doaj.org/article/26d62b137ac940e9b88658d00ac4970e
Autor:
Mari Katsura, Yoshihiro Urade, Hiroko Nansai, Mika Kobayashi, Akashi Taguchi, Yukiko Ishikawa, Tomohiro Ito, Hisako Fukunaga, Hideto Tozawa, Yoko Chikaoka, Ryo Nakaki, Akinobu Echigo, Takahide Kohro, Hideko Sone, Youichiro Wada
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract The effects of low-dose radiation on undifferentiated cells carry important implications. However, the effects on developing retinal cells remain unclear. Here, we analyzed the gene expression characteristics of neuronal organoids containing
Externí odkaz:
https://doaj.org/article/6849065892ea40a1a85340298c3e35b4
Autor:
Lin Pan, Amelia Trimarco, Alice J Zhang, Ko Fujimori, Yoshihiro Urade, Lu O Sun, Carla Taveggia, Ye Zhang
Publikováno v:
eLife, Vol 12 (2023)
In the developing central nervous system, oligodendrocyte precursor cells (OPCs) differentiate into oligodendrocytes, which form myelin around axons. Oligodendrocytes and myelin are essential for the function of the central nervous system, as evidenc
Externí odkaz:
https://doaj.org/article/8adbcb1ecf924139b56a96be47350b1c
Autor:
Takashi Shimizu, Akashi Taguchi, Yoshiki Higashijima, Yasuharu Kanki, Ryo Nakaki, Yoshihiro Urade, Youichiro Wada
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Peripartum cardiomyopathy (PPCM) is a life-threatening heart failure occurring in the peripartum period. Although mal-angiogenesis, induced by the 16-kDa N-terminal prolactin fragment (16 K PRL), is involved in the pathogenesis, the effect o
Externí odkaz:
https://doaj.org/article/bd475300e3704da38011878cdf321845
Autor:
Shintaro Shirahama, Kenzui Taniue, Shuhei Mitsutomi, Rie Tanaka, Toshikatsu Kaburaki, Tomohito Sato, Masaru Takeuchi, Hidetoshi Kawashima, Yoshihiro Urade, Makoto Aihara, Nobuyoshi Akimitsu
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-6 (2021)
Abstract Acute retinal necrosis (ARN) is a form of infectious uveitis caused by alpha herpesviruses, including herpes simplex virus type 1 (HSV-1). We previously found that the long non-coding RNA (lncRNA) U90926 is upregulated in murine retinal phot
Externí odkaz:
https://doaj.org/article/ad60a8f25b2c41328ab7650da450b5fd
Autor:
Kenny Kuchta, Kosuke Aritake, Yoshihiro Urade, Nguyen Huu Tung, Chun-Su Yuan, Yui Sasaki, Koichi Shimizu, Yukihiro Shoyama
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2022)
The objective of this review is to evaluate the anti-dementia activities of saffron and its combination with Kampo medicine. The Kampo formula Kamiuntanto composed of 13 crude drugs is well known for its anti-dementia activity. A significant increase
Externí odkaz:
https://doaj.org/article/80ed594de14a40d7be619259f3cf20a2
Autor:
Yoshihiro Urade
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Lipocalin-type prostaglandin (PG) D2 synthase (L-PGDS) catalyzes the isomerization of PGH2, a common precursor of the two series of PGs, to produce PGD2. PGD2 stimulates three distinct types of G protein-coupled receptors: (1) D type of prostanoid (D
Externí odkaz:
https://doaj.org/article/dd123f1a040047b4ba0b2893acbd2fd7
Autor:
Burkhard Schütz, Anna-Lena Ruppert, Oliver Strobel, Michael Lazarus, Yoshihiro Urade, Markus W. Büchler, Eberhard Weihe
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Abstract Despite considerable recent insight into the molecular phenotypes and type 2 innate immune functions of tuft cells in rodents, there is sparse knowledge about the region-specific presence and molecular phenotypes of tuft cells in the human d
Externí odkaz:
https://doaj.org/article/c432bbd8a8604289aa9dc0f6fac71f61
Autor:
Takashi Shimizu, Akashi Taguchi, Yoshiki Higashijima, Naoko Takubo, Yasuharu Kanki, Yoshihiro Urade, Youichiro Wada
Publikováno v:
iScience, Vol 23, Iss 8, Pp 101410- (2020)
Summary: Oxidative/nitrosative stress is a major trigger of cardiac dysfunction, involving the unfolded protein response and mitochondrial dysfunction. Activation of nitric oxide-cyclic guanosine monophosphate-protein kinase G signaling by sildenafil
Externí odkaz:
https://doaj.org/article/d2b7022ffed54aaf96275dbbf81ff3cf
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-2 (2021)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/cd682170c0e34a23bd134afcffbee04b