Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Yoshihiro, Miyashita"'
Autor:
Yuki Nagakubo, Yosuke Hirotsu, Mona Yoshino, Kenji Amemiya, Ryota Saito, Yumiko Kakizaki, Toshiharu Tsutsui, Yoshihiro Miyashita, Taichiro Goto, Masao Omata
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Companion diagnostic (CDx) tests play important roles in identifying oncogenic driver genes and tailoring effective molecularly targeted therapies for lung cancer patients. In Japan, the Oncomine Dx target test (ODxTT) and the AmoyDx pan lun
Externí odkaz:
https://doaj.org/article/ff4cfae4f35e4d38a5686f8341916c0a
Autor:
Yoshihiro Miyashita, MD, Yosuke Hirotsu, PhD, Yuki Nagakubo, MS, Hiroaki Kobayashi, MD, Makoto Kawaguchi, MD, Koki Hata, MD, Ryota Saito, MD, Yumiko Kakizaki, MD, Toshiharu Tsutsui, PhD, Toshio Oyama, MD, Masao Omata, MD
Publikováno v:
JTO Clinical and Research Reports, Vol 5, Iss 6, Pp 100679- (2024)
Introduction: NSCLC is a leading cause of cancer-related mortality worldwide. Specific genetic alterations, such as MET exon 14 (METex14) skipping, have been identified in NSCLC, allowing targeted therapy. Tepotinib, a highly selective MET inhibitor,
Externí odkaz:
https://doaj.org/article/02b007faf1354427b6783f95d8c35a84
Autor:
Toshiharu Tsutsui, Koki Hata, Makoto Kawaguchi, Hiroaki Kobayashi, Yumiko Kakizaki, Yoshihiro Miyashita
Publikováno v:
Thoracic Cancer, Vol 14, Iss 23, Pp 2310-2313 (2023)
Abstract Cytokine release syndrome (CRS) is a severe and life‐threatening toxicity typically reported in chimeric antigen receptor T cell therapy and is rarely reported in immune checkpoint inhibitor (ICI) therapy. This study reports the case of a
Externí odkaz:
https://doaj.org/article/11ecdeb4035c47c5a54ff48734bc68bb
Autor:
Yosuke Hirotsu, Yumiko Kakizaki, Akitoshi Saito, Toshiharu Tsutsui, Syunya Hanawa, Haruna Yamaki, Syuichiro Ide, Makoto Kawaguchi, Hiroaki Kobayashi, Yoshihiro Miyashita, Masao Omata
Publikováno v:
Communications Medicine, Vol 3, Iss 1, Pp 1-10 (2023)
Hirotsu, Kakizaki et al. assess the presence of pneumonia and pathogenesis during infection with different SARS-CoV-2 variants. The prevalence of pneumonia differs depending on the infectious variant, with the lowest prevalence and mild lung pathogen
Externí odkaz:
https://doaj.org/article/8084e50cd55a4111ae8f7d5a4de3d95b
Autor:
Yosuke Hirotsu, Makoto Maejima, Masahiro Shibusawa, Yume Natori, Yuki Nagakubo, Kazuhiro Hosaka, Hitomi Sueki, Hitoshi Mochizuki, Toshiharu Tsutsui, Yumiko Kakizaki, Yoshihiro Miyashita, Masao Omata
Publikováno v:
International Journal of Infectious Diseases, Vol 122, Iss , Pp 486-491 (2022)
Objectives: Recently, the Omicron strain of SARS-CoV-2 has spread and replaced the previously dominant Delta strain. Several Omicron sublineages (BA.1, BA.1.1, and BA.2) have been identified, with in vitro and preclinical reports showing that the pat
Externí odkaz:
https://doaj.org/article/73f355ecea044d9e8c7e6d7f9b4eef26
Autor:
Hiroyuki Sakashita, Ken Uchibori, Yasuto Jin, Toshiharu Tsutsui, Takayuki Honda, Rie Sakakibara, Takahiro Mitsumura, Yoshihisa Nukui, Tsuyoshi Shirai, Masahiro Masuo, Kozo Suhara, Haruhiko Furusawa, Takaaki Yamashita, Takehiko Ohba, Kazuhito Saito, Jun Takagiwa, Yoshihiro Miyashita, Naohiko Inase, Yasunari Miyazaki
Publikováno v:
Thoracic Cancer, Vol 13, Iss 9, Pp 1267-1275 (2022)
Abstract Background A standard treatment regimen for advanced non‐small cell lung cancer (NSCLC) patients with interstitial lung disease (ILD) has not been established since most clinical trials exclude such patients because of the high risk of acu
Externí odkaz:
https://doaj.org/article/fe5bbcf9dbb64b87b0926aa52b897ff9
Urinary L-Type Fatty Acid-Binding Protein Predicts Oxygen Demand of COVID-19 in Initially Mild Cases
Autor:
Daisuke Katagiri, MD, PhD, FASN, Yusuke Asai, PhD, Norio Ohmagari, MD, PhD, Masahiro Ishikane, MD, PhD, Sayaka Hikida, MD, PhD, Noriko Iwamoto, MD, PhD, Maki Nagashima, MT, Minami Suzuki, MD, PhD, Hideki Takano, MD, PhD, Jin Takasaki, MD, Masayuki Hojo, MD, PhD, Haruhito Sugiyama, MD, PhD, Katsushi Tokunaga, PhD, Yoshihiro Miyashita, MD, Masao Omata, MD, PhD, Keiichi Ohata, MS, Kevin P. Bliden, MBA, Udaya S. Tantry, PhD, Jeffrey R. Dahlen, PhD, Takeshi Sugaya, PhD, Paul A. Gurbel, MD, FACC, Eisei Noiri, MD, PhD, FASN
Publikováno v:
Critical Care Explorations, Vol 5, Iss 3, p e0873 (2023)
IMPORTANCE:. Early detection of illness trajectory in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infected patients is crucial for patients and healthcare workers. An effective, noninvasive approach, with simple measurement for decis
Externí odkaz:
https://doaj.org/article/c441b337caae44d7ad8b8954bdd690ac
Autor:
Yosuke Hirotsu, Makoto Maejima, Masahiro Shibusawa, Yume Natori, Yuki Nagakubo, Kazuhiro Hosaka, Hitomi Sueki, Kenji Amemiya, Miyoko Hayakawa, Hitoshi Mochizuki, Toshiharu Tsutsui, Yumiko Kakizaki, Yoshihiro Miyashita, Masao Omata
Publikováno v:
BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Background The nucleic acid amplification test (NAAT) and antigen test are approved diagnostic tests for COVID-19. In this study, we aimed to investigate the assay performance of two NAATs (Xpert Xpress SARS-CoV-2 and FilmArray Respiratory P
Externí odkaz:
https://doaj.org/article/751d23150ddd423597e4705622e9b830
Autor:
Masao Omata, Yosuke Hirotsu, Hiroki Sugiura, Makoto Maejima, Yuki Nagakubo, Kenji Amemiya, Miyoko Hayakawa, Toshiharu Tsutsui, Yumiko Kakizaki, Hitoshi Mochizuki, Yoshihiro Miyashita
Publikováno v:
Journal of Microbiology, Immunology and Infection, Vol 54, Iss 5, Pp 830-838 (2021)
Background: Currently, PCR assay is a golden standard for diagnosis of Covid-19. However, it needs nasopharyngeal swabs, expensive instruments and expertise. It even causes PCR errors. Methods: We validated the antibody assay (Roche) in 36 followed p
Externí odkaz:
https://doaj.org/article/c58044cae40143e98c5c7e8a3e240724
Autor:
Yosuke Hirotsu, Hiroki Sugiura, Makoto Maejima, Miyoko Hayakawa, Hitoshi Mochizuki, Toshiharu Tsutsui, Yumiko Kakizaki, Yoshihiro Miyashita, Masao Omata
Publikováno v:
International Journal of Infectious Diseases, Vol 108, Iss , Pp 263-269 (2021)
Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to spread worldwide. Here, we evaluated the performance of two quantitative antigen (Ag) tests, the Roche and Lumipulse Ag tests, using automated platforms. Methods: W
Externí odkaz:
https://doaj.org/article/b8256eedd8aa41c2b444beb2268a1aa9