Zobrazeno 1 - 10
of 161
pro vyhledávání: '"Yoshihiro, Ikura"'
Autor:
Keisuke Kakisaka, Nobuaki Nakayama, Kotaro Kumagai, Takuro Hisanaga, Takayuki Kondo, Toru Setsu, Shunsuke Sato, Yohei Kooka, Kei Endo, Yuichi Yoshida, Takayoshi Oikawa, Hidekatsu Kuroda, Akio Miyasaka, Ryuzo Abe, Taka-aki Nakada, Yoshihiro Ikura, Kenichi Harada, Takuya Genda, Shuji Terai, Naoya Kato, Taro Takami, Akio Ido, Satoshi Mochida, Takayuki Matsumoto, Atsushi Tanaka
Publikováno v:
Gastro Hep Advances, Vol 2, Iss 4, Pp 497-504 (2023)
Background and Aims: Acute liver injury (ALI) due to autoimmune hepatitis (AIH) can be treated by immunosuppression. In contrast, idiosyncratic drug-induced liver injury (DILI) had a poor prognosis. DILI thus needs to be distinguished from non-DILI.
Externí odkaz:
https://doaj.org/article/41e7930ab9084fc1bab5aaa463fc1040
Autor:
Dinh Viet Hoang, Le Thi Thanh Thuy, Hoang Hai, Vu Ngoc Hieu, Kenjiro Kimura, Daisuke Oikawa, Yoshihiro Ikura, Ninh Quoc Dat, Truong Huu Hoang, Misako Sato-Matsubara, Minh Phuong Dong, Ngo Vinh Hanh, Sawako Uchida-Kobayashi, Fuminori Tokunaga, Shoji Kubo, Naoko Ohtani, Katsutoshi Yoshizato, Norifumi Kawada
Publikováno v:
Oncogenesis, Vol 11, Iss 1, Pp 1-13 (2022)
Abstract Pancreatic cancer is a highly challenging malignancy with extremely poor prognosis. Cytoglobin (CYGB), a hemeprotein involved in liver fibrosis and cancer development, is expressed in pericytes of all organs. Here, we examined the role of CY
Externí odkaz:
https://doaj.org/article/cd03332a8f1a4b8a91e1f4acb0f2336f
Autor:
Eiichi Ogawa, Atsushi Tanaka, Kenichi Harada, Hiroshi Yatsuhashi, Kazumoto Murata, Masamichi Kimura, Jun Imamura, Masanao Saio, Yoshihiro Ikura, Kouichi Miura, Ichiro Ieiri, Kiminori Kimura
Publikováno v:
BMJ Open Gastroenterology, Vol 9, Iss 1 (2022)
Objective This study aimed to evaluate the safety and tolerability of OP-724, a CREB-binding protein/β-catenin inhibitor, in patients with advanced primary biliary cholangitis (PBC).Design An open-label, non-randomised, phase 1 trial was conducted a
Externí odkaz:
https://doaj.org/article/cabfe85f53b94df4a8a96a71c3bfa66f
Autor:
Kiminori Kimura, Tatsuya Kanto, Shinji Shimoda, Kenichi Harada, Masamichi Kimura, Koji Nishikawa, Jun Imamura, Eiichi Ogawa, Masanao Saio, Yoshihiro Ikura, Takuji Okusaka, Kazuaki Inoue, Tetsuya Ishikawa, Ichiro Ieiri, Junji Kishimoto, Koji Todaka, Terumi Kamisawa
Publikováno v:
EBioMedicine, Vol 80, Iss , Pp 104069- (2022)
Summary: Background: We conducted an exploratory study to assess the safety tolerability, and anti-fibrotic effects of PRI-724, a CBP/β-catenin inhibitor, in patients with hepatitis C virus (HCV)- and hepatitis B virus (HBV)-induced cirrhosis. Metho
Externí odkaz:
https://doaj.org/article/a68a8544980a4b5a8162b15098cfe871
Autor:
Takafumi Fukui, Takako Okubo, Naoki Tanimoto, Hiromichi Okuma, Yoshitaka Shiina, Mizuki Kohama, Jun Yamada, Yasuhiro Funada, Yoshihiro Ikura
Publikováno v:
Thoracic Cancer, Vol 12, Iss 6, Pp 974-977 (2021)
Abstract Here, we report a case of malignant pleural mesothelioma (MPM) that was very difficult to diagnose. A 62‐year‐old woman with a surgical history of recurrent bilateral pneumothorax was admitted to our hospital with severe dysphagia. Compu
Externí odkaz:
https://doaj.org/article/6c1d3a5ab07d4d6c960f9b21fd54ff20
Publikováno v:
Clinical Case Reports, Vol 9, Iss 12, Pp n/a-n/a (2021)
Abstract Lymphangiomas are benign, often subclinical, neoplasms, which can develop in the digestive tracts. Hemorrhagic jejunal tumors are relatively rare and diagnostic challenge. We report herein a case of hemorrhagic jejunal hemolymphangioma succe
Externí odkaz:
https://doaj.org/article/8b964d03249d4ee7be41934a7510d620
Publikováno v:
Infection. 51:545-547
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f94a97cd4d14acc6c7bc28d295afc5f1
https://doi.org/10.1007/s15010-022-01868-x
https://doi.org/10.1007/s15010-022-01868-x
Autor:
Masamichi Kimura, Eiichi Ogawa, Kenichi Harada, Jun Imamura, Masanao Saio, Yoshihiro Ikura, Hiroshi Yatsuhashi, Kazumoto Murata, Kouichi Miura, Ichiro Ieiri, Atsushi Tanaka, Kiminori Kimura
Publikováno v:
BMJ open gastroenterology. 9(1)
ObjectiveThis study aimed to evaluate the safety and tolerability of OP-724, a CREB-binding protein/β-catenin inhibitor, in patients with advanced primary biliary cholangitis (PBC).DesignAn open-label, non-randomised, phase 1 trial was conducted at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef8db65eab20b9a1335b56c17a76348b
https://pubmed.ncbi.nlm.nih.gov/36442892
https://pubmed.ncbi.nlm.nih.gov/36442892
Publikováno v:
Internal Medicine
Acute appendicitis is an important differential diagnosis in patients with right lower quadrant pain during pregnancy. Endometriosis, a hormone-related pathology, is another possibility. Patients with endometriosis are typically symptomatic before pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a0bf2774c3cdcb1e69ee8fcd99121b5
https://doi.org/10.2169/internalmedicine.5960-20
https://doi.org/10.2169/internalmedicine.5960-20
Autor:
Jun Yamada, Yasuhiro Funada, Takafumi Fukui, Takako Okubo, Naoki Tanimoto, Yoshitaka Shiina, Mizuki Kohama, Yoshihiro Ikura, Hiromichi Okuma
Publikováno v:
Thoracic Cancer
Thoracic Cancer, Vol 12, Iss 6, Pp 974-977 (2021)
Thoracic Cancer, Vol 12, Iss 6, Pp 974-977 (2021)
Here, we report a case of malignant pleural mesothelioma (MPM) that was very difficult to diagnose. A 62‐year‐old woman with a surgical history of recurrent bilateral pneumothorax was admitted to our hospital with severe dysphagia. Computed tomog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bce2bb30c3483fcf9fb753ebfe8144d7
https://doi.org/10.1111/1759-7714.13877
https://doi.org/10.1111/1759-7714.13877