Zobrazeno 1 - 10
of 2 053
pro vyhledávání: '"Yoshihiko Maehara"'
Autor:
Takeshi Wakasa, Kentaro Nonaka, Akihito Harada, Yasuyuki Ohkawa, Chie Kikutake, Mikita Suyama, Takashi Kobunai, Kenta Tsunekuni, Kazuaki Matsuoka, Yuki Kataoka, Hiroaki Ochiiwa, Kazutaka Miyadera, Takeshi Sagara, Eiji Oki, Shigehiro Ohdo, Yoshihiko Maehara, Makoto Iimori, Hiroyuki Kitao
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-12 (2024)
Abstract The fluorinated thymidine analog trifluridine (FTD) is a chemotherapeutic drug commonly used to treat cancer; however, the mechanism by which FTD induces cytotoxicity is not fully understood. In addition, the effect of gain-of-function (GOF)
Externí odkaz:
https://doaj.org/article/d0e4286119c6423db3d09770e905d4cc
Autor:
Fumihiro Shoji, Masafumi Yamaguchi, Masaki Okamoto, Shinkichi Takamori, Koji Yamazaki, Tatsuro Okamoto, Yoshihiko Maehara
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Cancer immunotherapy including immune checkpoint inhibitors (ICI) has revolutionized non-small cell lung cancer (NSCLC) therapy. Recently, the microbiota status “before” initiation of ICI therapy has been emphasized as a predictive biomarker in p
Externí odkaz:
https://doaj.org/article/2c491195b5a042a58d0d612f840111bd
Autor:
Koichi Kimura, Eisuke Adachi, Sachie Omori, Ayako Toyohara, Takahiro Higashi, Kippei Ohgaki, Shuhei Ito, Shin-ichiro Maehara, Toshihiko Nakamura, Yoichi Ikeda, Yoshihiko Maehara
Publikováno v:
BMC Gastroenterology, Vol 21, Iss 1, Pp 1-7 (2021)
Abstract Background Percutaneous transhepatic gallbladder drainage (PTGBD) is recommended for acute cholecystitis patients at high risk for surgical treatment. However, there is no evidence about the best timing of surgery after PTGBD. Here, we retro
Externí odkaz:
https://doaj.org/article/75a0da237de04ed3831a16be66d02821
Autor:
Eiji Oki, Akitaka Makiyama, Yuji Miyamoto, Masahito Kotaka, Hirofumi Kawanaka, Keisuke Miwa, Akira Kabashima, Tomohiro Noguchi, Kotaro Yuge, Tomomi Kashiwada, Koji Ando, Mototsugu Shimokawa, Hiroshi Saeki, Yoshito Akagi, Hideo Baba, Yoshihiko Maehara, Masaki Mori
Publikováno v:
Cancer Medicine, Vol 10, Iss 2, Pp 454-461 (2021)
Abstract Background A previous Phase I/II study demonstrated that TAS‐102 (trifluridine/tipiracil [FTD/TPI]) plus bevacizumab (Bev) has encouraging efficacy and controllable safety for patients with previously treated metastatic colorectal cancer.
Externí odkaz:
https://doaj.org/article/13e4f89644bc4c1e85fd861d81c0eaa6
Autor:
Hiroki Inada, Miyako Udono, Kanae Matsuda-Ito, Kenichi Horisawa, Yasuyuki Ohkawa, Shizuka Miura, Takeshi Goya, Junpei Yamamoto, Masao Nagasaki, Kazuko Ueno, Daisuke Saitou, Mikita Suyama, Yoshihiko Maehara, Wataru Kumamaru, Yoshihiro Ogawa, Sayaka Sekiya, Atsushi Suzuki
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
The conditions to induce human hepatic progenitor cells from other cell types are unclear. Here, the authors reprogram human endothelial cells to hepatic progenitor cells by expressing FOXA3, HNF1A and HNF6, capable of giving rise to hepatocytes and
Externí odkaz:
https://doaj.org/article/3527de58b192426485e6dd796f38531e
Autor:
Kei Nishiyama, Mari Kurokawa, Michiko Torio, Yasunari Sakai, Mitsuru Arima, Shoko Tsukamoto, Satoshi Obata, Shogo Minamikawa, Kandai Nozu, Noriyuki Kaku, Yoshihiko Maehara, Koh-Hei Sonoda, Tomoaki Taguchi, Shouichi Ohga
Publikováno v:
BMC Medical Genetics, Vol 21, Iss 1, Pp 1-7 (2020)
Abstract Background Pierson syndrome (PS) is a rare autosomal recessive disorder, characterized by congenital nephrotic syndrome and microcoria. Advances in renal replacement therapies have extended the lifespan of patients, whereas the full clinical
Externí odkaz:
https://doaj.org/article/89410397a9ad484e82d6857e80d0f856
Publikováno v:
Acute Medicine & Surgery, Vol 6, Iss 4, Pp 400-403 (2019)
Background Open abdomen management (OAM) is used not only for trauma but also for treatment of peritonitis. However, the rate of successful fascial closure in patients with OAM remains low. Case Presentation The patient was a 38‐year‐old morbidly
Externí odkaz:
https://doaj.org/article/bedd53fb675140e49a87601ea6c45935
Autor:
Ryuichi Takemoto, Yoshitomo Motomura, Noriyuki Kaku, Yuko Ichimiya, Mamoru Muraoka, Shunsuke Kanno, Tamami Tanaka, Yasunari Sakai, Yoshihiko Maehara, Shouichi Ohga
Publikováno v:
BMC Infectious Diseases, Vol 19, Iss 1, Pp 1-5 (2019)
Abstract Background Bicycle-spoke injuries rarely cause late complications of infection, including sepsis and sepsis-associated encephalopathy, with appropriate treatments. Case presentation We experienced a 2-year-old girl who developed the signs of
Externí odkaz:
https://doaj.org/article/87cb6cb0a2ca464682d4ac793929c86b
Autor:
Naomichi Koga, Nobuhide Kubo, Hiroshi Saeki, Shun Sasaki, Tomoko Jogo, Kosuke Hirose, Yuichiro Nakashima, Eiji Oki, Yutaka Koga, Yoshinao Oda, Hisao Oiwa, Toshio Oiwa, Yoshihiko Maehara
Publikováno v:
Surgical Case Reports, Vol 5, Iss 1, Pp 1-6 (2019)
Abstract Background Primary amelanotic malignant melanoma of esophagus, which is a subtype of primary malignant melanoma of the esophagus (PMME), is a very rare disease with a poor prognosis. We herein report a case of the amelanotic type of PMME. Ca
Externí odkaz:
https://doaj.org/article/b8fffe8c22d14e6aac40e95272f2e57f
Autor:
SHUHEI ITO, KIPPEI OHGAKI, TETSURO KAWAZOE, SHOTA SATO, SHUNJI IKEDA, KEISEI KAKIZOE, HUANLIN WANG, TOSHIHIKO NAKAMURA, SHINICHIRO MAEHARA, EISUKE ADACHI, YOICHI IKEDA, YOSHIHIKO MAEHARA
Publikováno v:
Anticancer Research. 43:2055-2067
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::791c08fffe5ca8f77b4e58c35a4cc3f6
https://doi.org/10.21873/anticanres.16366
https://doi.org/10.21873/anticanres.16366