Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Yoshihide Kii"'
Autor:
Seiji Hayashi, Yoshihide Kii, Mitsuyasu Tabo, Hitoshi Fukuda, Tetsuji Itoh, Takashi Shimosato, Hideto Amano, Mamoru Saito, Hajime Morimoto, Kiyoshi Yamada, Atsuhiro Kanda, Toshimasa Ishitsuka, Takanobu Yamazaki, Yoichi Kiuchi, Shinya Taniguchi, Tatsuya Mori, Shigekazu Shimizu, Yuji Tsurubuchi, Shun-ichi Yasuda, Shin-ichi Kitani, Chiaki Shimada, Kazuo Kobayashi, Masaharu Komeno, Chieko Kasai, Toshiyasu Hombo, Keiji Yamamoto
Publikováno v:
Journal of Pharmacological Sciences, Vol 99, Iss 5, Pp 423-437 (2005)
To construct a non-clinical database for drug-induced QT interval prolongation, the electrophysiological effects of 11 positive and 10 negative compounds on action potentials (AP) in guinea-pig papillary muscles were investigated in a multi-site stud
Externí odkaz:
https://doaj.org/article/a0418258c79346d3ac043532653edbdc
Autor:
Yoshihide Kii, Seiji Hayashi, Mitsuyasu Tabo, Takashi Shimosato, Hitoshi Fukuda, Tetsuji Itoh, Hideto Amano, Mamoru Saito, Hajime Morimoto, Kiyoshi Yamada, Atsuhiro Kanda, Toshimasa Ishitsuka, Takanobu Yamazaki, Yoichi Kiuchi, Shinya Taniguchi, Tatsuya Mori, Shigekazu Shimizu, Yuji Tsurubuchi, Shun-ichi Yasuda, Shin-ichi Kitani, Chiaki Shimada, Kazuo Kobayashi, Masaharu Komeno, Chieko Kasai, Toshiyasu Hombo, Keiji Yamamoto
Publikováno v:
Journal of Pharmacological Sciences, Vol 99, Iss 5, Pp 449-457 (2005)
Certain compounds that prolong QT interval in humans have little or no effect on action-potential (AP) duration used traditionally, but they inhibit rapidly-activated-delayed-rectifier potassium currents (IKr) and/or human ether-a-go-go-related gene
Externí odkaz:
https://doaj.org/article/607f605ce3e84d8090d1635dfe43b73c
Autor:
Kazuo Kobayashi, Hideto Amano, Tetsuji Itoh, Mamoru Saito, Yoshihide Kii, Shinya Taniguchi, Yoichi Kiuchi, Takashi Shimosato, Shun-ichi Yasuda, Chieko Kasai, Yuji Tsurubuchi, Toshimasa Ishitsuka, Tatsuya Mori, Seiji Hayashi, Kiyoshi Yamada, Mitsuyasu Tabo, Hajime Morimoto, Chiaki Shimada, Hitoshi Fukuda, Shin-ichi Kitani, Atsuhiro Kanda, Keiji Yamamoto, Toshiyasu Hombo, Masaharu Komeno, Takanobu Yamazaki, Shigekazu Shimizu
Publikováno v:
Journal of Pharmacological Sciences, Vol 99, Iss 5, Pp 423-437 (2005)
To construct a non-clinical database for drug-induced QT interval prolongation, the electrophysiological effects of 11 positive and 10 negative compounds on action potentials (AP) in guinea-pig papillary muscles were investigated in a multi-site stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7f709bc0b147b24d29b688464309466
https://doi.org/10.1254/jphs.qt-a1
https://doi.org/10.1254/jphs.qt-a1
Effects of antihistamines, ebastine and terfenadine, on electrocardiogram in conscious dogs and cats
Autor:
Katsuyoshi Nakatsuji, Yoshihide Kii, Michiaki Matsuda, Masafumi Yabuuchi, Tsugutaka Ito, Isamu Nose
Publikováno v:
Drug Development Research. 58:209-217
The purpose of this study was to evaluate the effects of ebastine and terfenadine on the electrocardiogram of conscious dogs and cats. In dogs, terfenadine at oral doses of 30 mg/kg twice a day for 7 days prolonged the electrocardiographic QT interva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4225005f201a43ee06255f745ad4644f
https://doi.org/10.1002/ddr.10163
https://doi.org/10.1002/ddr.10163
Autor:
Yoshihide Kii, Tsugutaka Ito
Publikováno v:
Journal of Cardiovascular Pharmacology. 29:670-675
The purpose of this study was to examine the effects of 5-HT4-receptor agonists cisapride, mosapride citrate (mosapride), and zacopride on action potentials (APs) in guinea pig isolated papillary muscles. Cisapride (0.1-3 microM) concentration-relate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::732885baefc6561d633cc0df093ab3bf
https://doi.org/10.1097/00005344-199705000-00016
https://doi.org/10.1097/00005344-199705000-00016
Autor:
Toshimasa Ishitsuka, Masaharu Komeno, Shin-ichi Kitani, Kazuo Kobayashi, Shinya Taniguchi, Shun-ichi Yasuda, Toshiyasu Hombo, Yuji Tsurubuchi, Yoshihide Kii, Hajime Morimoto, Keiji Yamamoto, Tatsuya Mori, Tetsuji Itoh, Takanobu Yamazaki, Kiyoshi Yamada, Chieko Kasai, Mitsuyasu Tabo, Takashi Shimosato, Chiaki Shimada, Atsuhiro Kanda, Hitoshi Fukuda, Hideto Amano, Yoichi Kiuchi, Mamoru Saito, Shigekazu Shimizu, Seiji Hayashi
Publikováno v:
Journal of Pharmacological Sciences, Vol 99, Iss 5, Pp 449-457 (2005)
Certain compounds that prolong QT interval in humans have little or no effect on action-potential (AP) duration used traditionally, but they inhibit rapidly-activated-delayed-rectifier potassium currents (IKr) and/or human ether-a-go-go-related gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f069beb63d777b3d1c3835ebb5eb7be
https://pubmed.ncbi.nlm.nih.gov/16493186
https://pubmed.ncbi.nlm.nih.gov/16493186
Autor:
Yoshihide, Kii, Tsugutaka, Ito
Publikováno v:
Pharmacologytoxicology. 90(5)
The aims of this study were to develop a suitable model to study proarrhythmic potential using isolated rabbit hearts with atrioventricular block and to examine the proarrhythmic potential of several drugs using this model. With a normal K/Mg solutio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::61178c5f17bab4f202bf8d9317fb9da1
https://pubmed.ncbi.nlm.nih.gov/12076305
https://pubmed.ncbi.nlm.nih.gov/12076305
Autor:
Masafumi Yabuuchi, Isamu Nose, Tsugutaka Ito, Yasuyuki Mizuki, Katsuyoshi Nakatsuji, Yoshihide Kii
Publikováno v:
Pharmacologytoxicology. 89(2)
The purpose of this study was to examine the arrhythmogenic potential of 5-HT4 receptor agonists, cisapride and mosapride citrate (mosapride) in vivo. In anaesthetized rats, cisapride at intravenous infusion of 10 and 30 mg/kg/hr for 1 hr prolonged t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcde8609749ffb05a1f1942f5ca4da85
https://pubmed.ncbi.nlm.nih.gov/11555327
https://pubmed.ncbi.nlm.nih.gov/11555327
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 58:169-170
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36344eff36b11069499d88c4dffa2515
https://doi.org/10.1016/j.vascn.2008.05.097
https://doi.org/10.1016/j.vascn.2008.05.097
Autor:
Shinji Tsujimoto, Tadashi Tsubouchi, Takeshi Kunimatsu, Terumasa Mino, Kaori Kunito, Yoshihide Kii, Yasufumi Ibuchi
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 68:e49
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42e2216edf0c53b6525e761a4a608261
https://doi.org/10.1016/j.vascn.2013.01.175
https://doi.org/10.1016/j.vascn.2013.01.175