Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Yoshiharu Tsuru"'
Autor:
Haruka Orihara, Min Ma, Yoshiyasu Nagashima, Ryota Tochinai, Shin-ichi Sekizawa, Daiki Kato, Masahiro Shinada, Susumu Aoki, Naoki Fujita, Takayuki Nakagawa, Yoshiharu Tsuru, Yasuko Tatewaki, Tatsushi Mutoh, Yasuyuki Taki, Ryohei Nishimura, Masayoshi Kuwahara
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 160, Iss , Pp 114353- (2023)
Combretastatin A4 (CA4) inhibits microtubule polymerization, and clinical trials of the prodrug, CA4 disodium phosphate (CA4DP), as an anti-cancer agent have been conducted. However, CA4DP has not been marketed to date because the margin between the
Externí odkaz:
https://doaj.org/article/15c71be28b5a4022a94239de2e100d5d
Autor:
Ryota TOCHINAI, Koichi KIMURA, Takeru SAIKA, Wataru FUJII, Hiroyuki MORITA, Koki NAKANISHI, Yoshiharu TSURU, Shin-ichi SEKIZAWA, Keitaro YAMANOUCHI, Masayoshi KUWAHARA
Publikováno v:
Experimental Animals; 2024, Vol. 73 Issue 2, p145-153, 9p
Autor:
Yoshiyasu NAGASHIMA, Ryota TOCHINAI, Shin-ichi SEKIZAWA, Daiki KATO, Takayuki NAKAGAWA, Yoshiharu TSURU, Yasuko TATEWAKI, Tatsushi MUTOH, Yasuyuki TAKI, Masayoshi KUWAHARA
Publikováno v:
Journal of Toxicologic Pathology.
Autor:
Kazuhisa KISHI, Tomohiro YONEZAWA, Noriyuki KAJI, Momo GOTO, Yuma NONOSHITA, Aki IIO, Yoshiharu TSURU, Masatoshi HORI
Publikováno v:
Journal of Veterinary Medical Science.
Autor:
Mao Miyamoto, Ryota Tochinai, Kazuyuki Uchida, Shin-Ich Sekizawa, Masayoshi Kuwahara, Yoshiharu Tsuru, Takanori Shiga
Publikováno v:
Journal of Toxicologic Pathology. 33:227-236
Duchenne muscular dystrophy (DMD) is a progressive muscular disorder caused by X-chromosomal DMD gene mutations. Recently, a new CRISPR/Cas9-mediated DMD rat model (cDMDR) was established and is expected to show cardiac lesions similar to those in hu
Publikováno v:
Experimental Animals; 2023, Vol. 72 Issue 1, p68-76, 9p
Publikováno v:
Digestion. 102(5)
Introduction: Colonic motility disorders are a frequent clinical problem caused by various drugs and diseases. However, the etiology of colonic dysmotility is often unclear due to the lack of in vivo methods, including rapid dynamic assessment. Objec
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 95:2
Autor:
Kazumasu Sasaki, Ryuta Kawashima, Yasuyuki Taki, Shuzo Yamamoto, Yoshiharu Tsuru, Tatsushi Mutoh
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 45:859-862
We evaluated the neuroprotective role of rapamycin, a mammalian target of rapamycin (mTOR) kinase inhibitor, in cerebral ischaemia and locomotor function in a mouse model of subarachnoid haemorrhage (SAH). Pretreatment with rapamycin, an mTOR kinase
Publikováno v:
Experimental Animals
Upper gastrointestinal (GI) motility is affected by various drugs and diseases. However, changes in upper GI motility during these conditions are not well understood, as there are few quantitative in vivo methods that assess small intestinal motility