Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Yoshiharu Takashima"'
Autor:
Yoichi Konishi, Masahiro Tsutsumi, Yoshiharu Takashima, Toshifumi Tsujiuchi, Yasutaka Sasaki, Osamu Kusuoka
Publikováno v:
Journal of Toxicologic Pathology. 14:87-98
Safety assessment of endocrine-disrupting chemicals (EDCs) is now an important issue because of fear of human exposure. Bisphenol A (BPA), a compound initially synthesized as a chemical oestrogen, is now used as a monomer for the production of polyca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1eef27adaea2c3f2b14b51beda9c545c
https://doi.org/10.1293/tox.14.87
https://doi.org/10.1293/tox.14.87
Autor:
Kazuhiko Suzuki, Takashi Nagayama, Yasuo Yoneta, Kazuichi Nakamura, Chihiro Tamaki, Masanori Hizue, Yamato Ogino, Daisaku Yasugi, Masamichi Hashiba, Yoshiharu Takashima, Hiroshi Kodaira, Masato Fujiyoshi, Minoru Nishida, Shigeru Hisada, Takako Ohkura
Publikováno v:
The Journal of toxicological sciences. 38(4)
The objective of this study was to elucidate the range of abilities of nonclinical safety assessment for predicting adverse drug reactions (ADRs) in humans. The dataset included 1256 ADRs with an incidence rate of 5% or more collected from 142 drugs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea3288624d1998cdff9d0fa3bf569d5b
https://pubmed.ncbi.nlm.nih.gov/23824014
https://pubmed.ncbi.nlm.nih.gov/23824014
Publikováno v:
BUNSEKI KAGAKU. 42:T77-T81
殺虫製剤(エアゾール,蚊取線香,蚊取マット等)中の有効成分を,キャピラリーガスクロマトグラフィーを用いて一斉分析する方法を確立した.今回の検討では,一般に使用されている9種類の
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50437cb00d4acd93d0f6cf1c91e5ed70
https://doi.org/10.2116/bunsekikagaku.42.5_t77
https://doi.org/10.2116/bunsekikagaku.42.5_t77
Autor:
Ayumi Denda, Yoichi Konishi, Hiroshi Maruyama, Yoshiharu Takashima, Shunji Kitazawa, Masahiro Tsutsumi, Dai Nakae
Publikováno v:
Journal of Toxicologic Pathology. 3:57-63
The initiating potential of acetaminophen (APAP) was investigated in prexisting fatty liver induced by choline-devoid (CD) diet in male F344 rats. APAP was intragastrically administered at the single necrogenic doses, 0.5g/kg, 1.0g/kg, 1.5g/kg body w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90b74194a9eedbafbf66922f1ebecb46
https://doi.org/10.1293/tox.3.57
https://doi.org/10.1293/tox.3.57
Autor:
Hiroyuki Eimoto, Yoichi Konishi, Kazuhiko Yamamoto, M. Sugimura, Yoshiharu Takashima, Toshifumi Tsujiuchi, Akira Nakajima
Publikováno v:
Experimental Pathology. 38:53-59
Summary Dose response to the carcinogenic activity of N-nitrosomethyl(2-hydroxypropyl)amine (MHP) was investigated for the nasal cavity of male Wistar rats. MHP dissolved in 0.9% saline was administered intraperitoneally once a week for 12 weeks at d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1739cb8239a4afef5b88a0e51b91aa76
https://doi.org/10.1016/s0232-1513(11)80198-2
https://doi.org/10.1016/s0232-1513(11)80198-2
Autor:
Masataka Murase, Yoshihiro Kawase, Toshinori Okouchi, Tadashi Yamaguchi, Tatsuya Masuda, Yoshiharu Takashima
Publikováno v:
Computer Engineering in Applied Electromagnetism ISBN: 1402031688
Recently, it is necessary to improve the higher energy efficiency for various motors. A skeleton type single-phase permanent magnet motor is analyzed using the finite element method, and the effects of the stator in different shapes and the rotation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d876510bbe016b078cf1c4593aeee86d
https://doi.org/10.1007/1-4020-3169-6_27
https://doi.org/10.1007/1-4020-3169-6_27
Publikováno v:
Proceedings 199 IEEE/IEEJ/JSAI International Conference on Intelligent Transportation Systems (Cat. No.99TH8383).
Reports the performance resulting from a change of operation of signal units to make them responsive to the speed of travelling vehicles and thus reducing the number of accidents occurring. The attempt was prompted by the fact that traffic accidents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4306c7c70493941891c5fe363f375056
https://doi.org/10.1109/itsc.1999.821115
https://doi.org/10.1109/itsc.1999.821115
Autor:
Toshihiro Amanuma, Yoichi Konishi, Hitoshi Yoshiji, Dai Nakae, Yoshiharu Takashima, Toshifumi Tsujiuchi, Hiroshi Maruyama, Ayumi Denda, Masahiro Tsutsumi
Publikováno v:
Carcinogenesis. 13(8)
The modifying effects of an immunosuppressive agent, 6-mercaptopurine (6-MP), on development of focal lesions in liver cirrhosis models induced by carbon tetrachloride (CCl4) or furfural were studied in male F344 rats. Feeding of 6-MP at 50 p.p.m. fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15bc3fc105c938626f2e7ec1a86ec02d
https://pubmed.ncbi.nlm.nih.gov/1354082
https://pubmed.ncbi.nlm.nih.gov/1354082
Autor:
Dai Nakae, Yoichi Konishi, Hiroyuki Eimoto, Yoshiharu Takashima, Hiroshi Maruyama, Yoshiaki Murata, Ayumi Denda, Masahiro Tsutsumi
Publikováno v:
Carcinogenesis. 11(6)
The potential carcinogenic activity of acetaminophen (paracetamol, APAP) was studied in male F344 rats with pre-existing liver damage induced by a choline-devoid (CD) diet. In a short-term experiment, APAP was administered by intragastric intubation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cc29db1575741a7d01a3dc997fe01d7
https://pubmed.ncbi.nlm.nih.gov/2347065
https://pubmed.ncbi.nlm.nih.gov/2347065
Autor:
KAZUHIKO, YAMAMOTO, HIROSHI, EIMOTO, YOSHIHARU, TAKASHIMA, MASAHIRO, TSUTSUMI, HIROSHI, MARUYAMA, AYUMI, DENDA, YUKIO, MORI, YOICHI, KONISHI
Publikováno v:
岐阜藥科大學紀要 = The annual proceedings of Gifu College of Pharmacy. 39:102
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=jairo_______::b2cd50ecacb92e7d2effbe1773c451af
http://id.nii.ac.jp/1076/00008600/
http://id.nii.ac.jp/1076/00008600/