Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Yoshiharu, Akitake"'
Autor:
Sei Higuchi, Keiichi Irie, Shohei Mishima, Maiko Araki, Makiko Ohji, Atsunori Shirakawa, Yoshiharu Akitake, Kiyoshi Matsuyama, Kenji Mishima, Kenichi Mishima, Katsunori Iwasaki, Michihiro Fujiwara
Publikováno v:
Journal of Pharmacological Sciences, Vol 112, Iss 3, Pp 369-372 (2010)
Endocannabinoids have been shown to activate reward-related feeding and to promote astrocytic differentiation. We investigated whether high-fat diet (HFD) intake produced a preference for HFD via an endocannabinoid-dependent mechanism. In the conditi
Externí odkaz:
https://doaj.org/article/f44a738a89634a5ab4701c47c7671d7e
Autor:
Sei Higuchi, Keiichi Irie, Ryuji Yamaguchi, Mai Katsuki, Maiko Araki, Makiko Ohji, Kazuhide Hayakawa, Shohei Mishima, Yoshiharu Akitake, Kiyoshi Matsuyama, Kenji Mishima, Kenichi Mishima, Katsunori Iwasaki, Michihiro Fujiwara
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38609 (2012)
In this study, we examined alterations in the hypothalamic reward system related to high-fat diet (HFD) preferences. We previously reported that hypothalamic 2-arachidonoylglycerol (2-AG) and glial fibrillary acid protein (GFAP) were increased after
Externí odkaz:
https://doaj.org/article/6054f09cce2a4cc28d444008b97511cf
Autor:
Mikiya Miyazato, Toru Kimura, Yoshiharu Akitake, Jun Hino, Koichi Miura, Hiroshi Hosoda, Takashi Nojiri, Kenji Kangawa, Masahiro Zenitani, Shigetomo Fukuhara, Koji Ando
Publikováno v:
Biochemical Journal. 474:1897-1918
Atrial natriuretic peptide (ANP) is a cardiac hormone released by the atrium in response to stretching forces. Via its receptor, guanylyl cyclase-A (GC-A), ANP maintains cardiovascular homeostasis by exerting diuretic, natriuretic, and hypotensive ef
Autor:
Koichi Miura, Takeshi Tokudome, Shin Ishikane, Mikiya Miyazato, Yumiko Toyohira, Fumi Takahashi-Yanaga, Yoshitaka Imamichi, Shinya Kawabe, Nobuyuki Yanagihara, Hiroshi Hosoda, Tetsuya Mizutani, Yoshiharu Akitake, Toru Kimura, Kenji Kangawa, Kaoru Miyamoto, Takashi Nojiri
Publikováno v:
Biochemical pharmacology. 154
Hypertension is considered as one of the cancer progressive factors, and often found comorbidity in cancer patients. Renin-angiotensin system (RAS) plays an important role in the regulation of blood pressure, and angiotensin II (Ang II) is well known
Autor:
Kenichi Mishima, Shinji Katsuragi, Masato Hosokawa, Hiroshi Hosoda, Tomoaki Ikeda, Yoshiharu Akitake, Mikiya Miyazato
Publikováno v:
Nutrition Research. 35:76-87
Intrauterine growth retardation (IUGR) occurs in 3% to 7% of all pregnancies. Recent human studies have indicated that neurodevelopmental disabilities, learning disorders, memory impairment, and mood disturbance are common in IUGR offspring. However,
Autor:
Yoshiharu Akitake, Yumiko Toyohira, Hiroshi Hosoda, Shin Ishikane, Fumi Takahashi, Tomoaki Ikeda
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 92:3
Autor:
Shuntaro Hara, Daisuke Kamei, Masato Hosokawa, Ichiro Kudo, Shizuo Akira, Yoshihito Nakatani, Mitsuo Takahashi, Satoshi Uematsu, Yoshiharu Akitake, Hiroyasu Akatsu
Publikováno v:
Journal of Neuroscience Research. 91:909-919
Epidemiological studies have suggested that long-term use of nonsteroidal anti-inflammatory drugs that inhibit cyclooxygenase (COX) activity can moderate the onset or progression of Alzheimer's disease (AD). Thus it has been suggested that prostaglan
Autor:
Shuntaro Hara, Yoshihito Nakatani, Daisuke Kamei, Shizuo Akira, Yoshiharu Akitake, Yuka Sasaki, Mitsuo Takahashi, Satoshi Uematsu, Ichiro Kudo, Yukiko Kuroki
Publikováno v:
Biochemical and Biophysical Research Communications. 424:409-413
Epidemiological studies have suggested that the long-term use of nonsteroidal anti-inflammatory drugs that inhibit cyclooxygenase (COX) activity moderates the onset or progression of Alzheimer's disease (AD). Thus it has been suggested that prostagla
Autor:
Makiko Ohji, Kiyoshi Matsuyama, Sei Higuchi, Michihiro Fujiwara, Keiichi Irie, Kenichi Mishima, Kenji Mishima, Maiko Araki, Riyo Furuta, Ryuji Yamaguchi, Mai Katsuki, Yoshiharu Akitake, Katsunori Iwasaki
Publikováno v:
Behavioural Brain Research. 216:477-480
The aim of the present study is to examine the relationship between preference for HFD and 2-arachidonoylglycerol (2-AG), endogenous cannabinoid. The 3-day HFD intake induced preference for HFD, which was suppressed by CB1 antagonist, O-2050. Moreove
Autor:
Sei Higuchi, Maiko Araki, Kenji Mishima, Mai Katsuki, Ryuji Yamaguchi, Yoshiharu Akitake, Katsunori Iwasaki, Kenichi Mishima, Keiichi Irie, Riyo Furuta, Michihiro Fujiwara, Takafumi Nakano, Makiko Ohji, Kiyoshi Matsuyama, Yuya Sakamoto
Publikováno v:
Analytical Sciences. 26:1199-1202
Endocannabinoid 2-arachidonoylglycerol (2-AG) regulates several important physiological processes in the brain. 2-AG is commonly quantified by gas chromatography mass spectrometry after an initial purification step. The most precise and rapid purific