Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Yoshifumi Tachibana"'
Autor:
Uwe Platzbecker, Joerg Chromik, Jan Krönke, Hiroshi Handa, Stephen Strickland, Yasushi Miyazaki, Martin Wermke, Wataru Sakamoto, Yoshifumi Tachibana, Tillmann Taube, Ulrich Germing
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Background This report summarizes three phase I studies evaluating volasertib, a polo-like kinase inhibitor, plus azacitidine in adults with myelodysplastic syndromes (MDS), chronic myelomonocytic leukemia, or acute myeloid leukemia. Methods
Externí odkaz:
https://doaj.org/article/f154eb6140c84e199690ca1fd5d13890
Autor:
Yoshifumi Tachibana, Mamoru Narukawa
Background Existing studies and statistics on the drug lag between Japan and the United States (US) for anticancer drugs indicate that it has decreased, whereas more drugs are left unapproved in Japan. This study aimed to quantify the impact of unapp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27bdfd663f60edc3276f3338b25c70d0
https://doi.org/10.21203/rs.3.rs-2792303/v1
https://doi.org/10.21203/rs.3.rs-2792303/v1
Autor:
Kosuke Shiki, Naoko Tajima, Tatsuroh Kaneko, Jisoo Lee, Hirohito Sone, Egon Pfarr, Yoshifumi Tachibana
Publikováno v:
Diabetes, Obesity & Metabolism
Aim To assess the efficacy and safety of empagliflozin as add‐on to insulin in Japanese patients with type 2 diabetes (T2D). Materials and methods This multicentre, double‐blind, parallel‐group study randomized Japanese patients with T2D insuff
Autor:
Do-Youn Oh, Yoshifumi Tachibana, Yasutoshi Kuboki, Yoon-Koo Kang, Mabrouk Elgadi, Hiroki Hara, Manabu Morimoto, Chia-Chi Lin, Kensei Yamaguchi, Jianrui Hou, Shigehisa Kitano, Sun Young Rha, Shunsuke Kondo
Publikováno v:
Annals of Oncology. 32:S310
Autor:
Manabu Morimoto, Sun Young Rha, Shigehisa Kitano, Yasutoshi Kuboki, Shunsuke Kondo, Mabrouk Elgadi, Jianrui Hou, Chia-Chi Lin, Yoshifumi Tachibana, Hiroki Hara, Do-Youn Oh, Yoon-Koo Kang, Kensei Yamaguchi
Publikováno v:
Journal of Clinical Oncology. 39:212-212
212 Background: Dual blockade of immune checkpoint molecules, PD-1 and LAG-3, has been proposed to restore T-cell function and thus enhance antitumor responses. This Phase I trial evaluated BI 754091 (anti-PD-1) with BI 754111 (anti-LAG-3) antibodies
Autor:
Shunsuke Kondo, Do-Youn Oh, Miaomiao Ge, Kensei Yamaguchi, Shigehisa Kitano, Mabrouk Elgadi, Yoshifumi Tachibana, Manabu Morimoto, Sun Young Rha, Yasutoshi Kuboki, Yoon-Koo Kang, Chia-Chi Lin, Hiroki Hara
Publikováno v:
Journal of Clinical Oncology. 38:3054-3054
3054 Background: Dual blockade of immune checkpoint molecules, PD-1 and LAG-3, may enhance the anti-tumor response versus PD-1 blockade alone. This Phase I trial investigated BI 754091, an anti-PD-1 antibody, as monotherapy and in combination with BI
Autor:
Riyo Enomoto, Eibai Lee, Toshio Yokoi, Yoshifumi Tachibana, Gyöngyi Bökönyi, György Kéri, Anna Miyazaki, Yuko Tsuda, Yoshio Okada
Publikováno v:
Tetrahedron Letters. 45:6323-6327
It was reported that the somatostatin analog TT-232, d-Phe-c(Cys-Tyr-d-Trp-Lys-Cys)-Thr-NH2, exhibited a highly potent antitumor activity in vitro and in vivo. Using pyrazinone analogs and aliphatic amino acids instead of the disulfide bond, we prepa