Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Yoshifumi Okawa"'
Autor:
Yoko Taminishi-Katsuragawa, Naoki Maruyama, Yumi Iwamura, Yoshifumi Okawa, Saori Matsui-Maegawa, Chihiro Shimazaki, Mayumi Hatsuse, Shin-ichi Fuchida, Takaomi Suga, Akira Okano, Yohei Kitamura, Daisuke Ide, Satoshi Murakami
Publikováno v:
International Journal of Hematology. 111:803-811
The prognosis of cardiac light-chain (AL) amyloidosis is considered to be very poor. We studied the treatment efficacy and outcomes by retrospectively analyzing the clinical results of 45 patients with cardiac AL amyloidosis treated at our hospital b
Autor:
Motoki Uchihashi, Shuhei Tateishi, Satoaki Matoba, Kazunori Ono, Makoto Ariyoshi, Kuniyoshi Fukai, Satoshi Kaimoto, Yoshifumi Okawa, Eri Iwai-Kanai, Atsushi Hoshino
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 312:H305-H313
Failing heart loses its metabolic flexibility, relying increasingly on glucose as its preferential substrate and decreasing fatty acid oxidation (FAO). Peroxisome proliferator-activated receptor α (PPAR-α) is a key regulator of this substrate shift
Autor:
Yoshifumi Okawa
Publikováno v:
The Developing Economies. 56:68-70
Autor:
Tomoya Kitani, Eri Iwai-Kanai, Ryoetsu Yamanaka, Ryota Urata, Yoshifumi Okawa, Tomohiro Hino, Satoaki Matoba, Yoshito Minami, Shunta Taminishi, Daichi Hato, Nobuichiro Yagi, Sakiko Honda, Yohei Fushimura, Atsushi Hoshino, Ayumi Matsuki, Shyo Hashimoto, toshiyuki nishiji
Publikováno v:
Circulation Research. 125
Background: Although metabolic alterations were observed in heart failure (HF), only recently have the mechanisms underlying these changes been identified. Tumor suppressor p53 responds to metabolic changes thorough several mechanisms. One of the p53
Autor:
Satoaki Matoba, Yohei Fushimura, Yusuke Higuchi, Takehiro Ogata, Ryoetsu Yamanaka, Atsushi Hoshino, Kazunori Ono, Satoshi Kaimoto, Shuhei Tateishi, Yoshifumi Okawa, Kuniyoshi Fukai, Daichi Hato, Sakiko Honda, Makoto Ariyoshi, Eri Iwai-Kanai, Motoki Uchihashi
Publikováno v:
Circulation: Heart Failure. 10
Background Energy starvation and the shift of energy substrate from fatty acids to glucose is the hallmark of metabolic remodeling during heart failure progression. However, ketone body metabolism in the failing heart has not been fully investigated.
Autor:
Naohiko Nakanishi, Makoto Ariyoshi, Akihiro Nakamura, Atsushi Hoshino, Satoshi Kaimoto, Shuhei Tateishi, Koji Ikeda, Yoshifumi Okawa, Kuniyoshi Fukai, Kazunori Ono, Motoki Uchihashi, Satoaki Matoba, Tomomi Ueyama, Takehiro Ogata
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 308:H951-H959
Pulmonary arterial hypertension (PAH) is a refractory disease characterized by uncontrolled vascular remodeling and elevated pulmonary arterial pressure. Although synthetic inhibitors of some tyrosine kinases have been used to treat PAH, their therap
Autor:
Makoto Ariyoshi, Yohei Fushimura, Daichi Hato, Ryoetsu Yamanaka, Atsushi Hoshino, Masashi Mita, Naotada Ishihara, Satoaki Matoba, Eri Iwai-Kanai, Yuichiro Mita, Yurika Miyoshi, Maiko Nakane, Sakiko Honda, Syuhei Tateishi, Motoki Uchihashi, Hiroshi Homma, Masumi Katane, Kuniyoshi Fukai, Yoshifumi Okawa, Kazunori Ono, Kenji Hamase, Satoshi Kaimoto
Publikováno v:
Scientific Reports
D-Amino acids are enantiomers of L-amino acids and have recently been recognized as biomarkers and bioactive substances in mammals, including humans. In the present study, we investigated functions of the novel mammalian mitochondrial protein 9030617
Autor:
Tomomi Ueyama, Maki Katamura, Satoaki Matoba, Mikihiko Nakaoka, Eri Iwai-Kanai, Masaki Kimata, Atsushi Hoshino, Koji Ikeda, Hiroaki Matsubara, Yoshifumi Okawa, Makoto Ariyoshi, Hideo Nakamura, Mitsuhiko Okigaki, Yuichiro Mita
Publikováno v:
Journal of Molecular and Cellular Cardiology. 52:175-184
Inhibition of tumor suppressor p53 is cardioprotective against ischemic injury and provides resistance to subsequent cardiac remodeling. We investigated p53-mediated expansion of ischemic damage with a focus on mitochondrial integrity in association
Autor:
Yoshifumi Okawa
Publikováno v:
Review of International Economics. 18:835-848
This paper extends the established Helpman (1993) model by introducing international capital movement, and obtains new results concerning the welfare implications of tightening intellectual property rights (IPR) in the South. First, if separated capi
Autor:
Yoshifumi Okawa
Publikováno v:
Studies in Regional Science. 39:823-837