Zobrazeno 1 - 10
of 168
pro vyhledávání: '"Yoshifumi Jigami"'
Autor:
Yoshifumi Jigami, Daisuke Ichikawa, Noriyuki Kanzawa, Taroh Kinoshita, Akiko Komatsuzaki, Ryo Taguchi, Kumiko Takase, Takehiko Yoko-o, Kazunobu Saito, Mariko Umemura, Kazutaka Ikeda
Publikováno v:
Genes to Cells. 23:880-892
Yeasts have two classes of glycosylphosphatidylinositol (GPI)-anchored proteins; one is transferred to the cell wall, whereas the other is retained on the plasma membrane. The lipid moieties of the GPI in Saccharomyces cerevisiae consist of either ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0007e6fedaf5e1c4804cf7303bcc0d1
https://doi.org/10.1111/gtc.12636
https://doi.org/10.1111/gtc.12636
Protease-DeficientSaccharomycescerevisiaeStrains for the Synthesis of Human-Compatible Glycoproteins
Autor:
Kazuya Tomimoto, Tomoko Iwaki, Hiroko Abe, Yasunori Chiba, Ken-ichi Nakayama, Yoshihiro Nakajima, Yoshifumi Jigami, Yasuko Fujita
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 77:2461-2466
Saccharomyces cerevisiae strains engineered previously to produce proteins with mammalian high mannose structures showed severe growth defects and decreased protein productivity. In strain YAB101, derived from one of these strains by a mutagenesis te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2a932bceedbc025ce57fac668d84de5
https://doi.org/10.1271/bbb.130588
https://doi.org/10.1271/bbb.130588
Autor:
Akiko Kato, Takehiko Yoko-o, Ryo Taguchi, Kazutaka Ikeda, Yoshifumi Jigami, Daisuke Ichikawa, Moonjin Ra, Kumiko Takase, Mariko Umemura, Yasunori Miyagishi
Publikováno v:
Molecular Microbiology. 88:140-155
Summary In the yeast Saccharomyces cerevisiae, glycosylphosphatidylinositol (GPI)-anchored proteins play important roles in cell wall biogenesis/assembly and the formation of lipid microdomains. The lipid moieties of mature GPI-anchored proteins in y
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5cf2b9486fcf90184c8659a3fba2ca4
https://doi.org/10.1111/mmi.12175
https://doi.org/10.1111/mmi.12175
Publikováno v:
Journal of Biological Chemistry. 287:10032-10038
Although selenium is an essential element, its excessive uptake is detrimental to living organisms. The significance of selenium for living organisms has been exploited for various purposes. However, the molecular basis of selenium toxicity is not co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad9be59a1f7be873a96342373a55d866
https://doi.org/10.1074/jbc.m111.324244
https://doi.org/10.1074/jbc.m111.324244
Autor:
Hitoshi Sakuraba, Tomoko Fukushige, Yasunori Chiba, Tadayasu Togawa, Takuro Kanekura, Toru Watanabe, Ikuo Kawashima, Takashi Kodama, Takahiro Tsukimura, Toshihiro Suzuki, Yoshifumi Jigami
Publikováno v:
Molecular Medicine. 18:76-82
To economically produce recombinant human α-galactosidase A (GLA) with a cell culture system that does not require bovine serum, we chose methylotrophic yeast cells with the OCH1 gene, which encodes α-1,6-mannosyltransferase, deleted and over-expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7d68cd06972ed7242c042633cbd7cc0
https://doi.org/10.2119/molmed.2011.00248
https://doi.org/10.2119/molmed.2011.00248
Publikováno v:
Journal of Biological Chemistry. 285:12390-12404
In eukaryotic cells, N-glycosylation has been recognized as one of the most common and functionally important co- or post-translational modifications of proteins. "Free" forms of N-glycans accumulate in the cytosol of mammalian cells, but the precise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03a5d0fe22e168e85fd45697ed3d0356
https://doi.org/10.1074/jbc.m109.082081
https://doi.org/10.1074/jbc.m109.082081
Autor:
Hisashi Narimatsu, Hiromi Ito, Yoshifumi Jigami, Yoshie Takahashi, Takashi Sato, Yasunori Chiba
Publikováno v:
Journal of Applied Glycoscience. 57:131-136
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::767a36671465211ec0add39ca821572a
https://doi.org/10.5458/jag.57.131
https://doi.org/10.5458/jag.57.131
Autor:
Yoh ichi Shimma, Yoshifumi Jigami, Fumie Saito, Yoshiyuki Nomura, Ken Matsuoka, Takehiko Yoko-o, Takuji Oka
Publikováno v:
Plant Physiology. 152:332-340
We characterized peptidyl hydroxyproline (Hyp) O-galactosyltransferase (HGT), which is the initial enzyme in the arabinogalactan biosynthetic pathway. An in vitro assay of HGT activity was established using chemically synthesized fluorescent peptides
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7808104f8eb5d40d1d380ff8bf626bd5
https://doi.org/10.1104/pp.109.146266
https://doi.org/10.1104/pp.109.146266
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 73:1398-1403
Saccharomyces cerevisiae strain TIY20, which produces a mammalian high-mannose type N-glycan, exhibits a severe growth defect due to disruption of yeast-specific outer chain mannosyltransferases. We have isolated a more fit strain, YAB103, from TIY20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::352ae53bc33e484ada060b319b33d383
https://doi.org/10.1271/bbb.90069
https://doi.org/10.1271/bbb.90069
Autor:
Satoshi Nishikawa, Emi Yagi, Toshihiko Kitajima, Yoshifumi Jigami, Tomomi Kubota, Yasunori Chiba
Publikováno v:
FEMS Yeast Research. 9:439-445
Yeast is widely used to determine the tertiary structure of eukaryotic proteins, because of its ability to undergo post-translational modifications such as glycosylation. A mutant lacking S-adenosylmethionine synthesis has been reported as a suitable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63a32dcb89926eed32e3b5d4035ee432
https://doi.org/10.1111/j.1567-1364.2009.00484.x
https://doi.org/10.1111/j.1567-1364.2009.00484.x