Zobrazeno 1 - 10
of 217
pro vyhledávání: '"Yoshifumi Itoh"'
Autor:
Ayumu Mubuchi, Mina Takechi, Shunsuke Nishio, Tsukasa Matsuda, Yoshifumi Itoh, Chihiro Sato, Ken Kitajima, Hiroshi Kitagawa, Shinji Miyata
Publikováno v:
eLife, Vol 12 (2024)
Radial neuronal migration is a key neurodevelopmental event for proper cortical laminar organization. The multipolar-to-bipolar transition, a critical step in establishing neuronal polarity during radial migration, occurs in the subplate/intermediate
Externí odkaz:
https://doaj.org/article/6a99df04125f444283a95d9bcb4a49cf
Autor:
Ryo Tanaka, Shosei Yoshinouchi, Kento Karouji, Yuki Tanaka, Tsukasa Tominari, Michiko Hirata, Chiho Matsumoto, Yoshifumi Itoh, Chisato Miyaura, Masaki Inada
Publikováno v:
FEBS Open Bio, Vol 13, Iss 1, Pp 51-59 (2023)
The pathologies and lethality of lung cancers are associated with smoking, lifestyle, and genomic factors. Several experimental mouse models of lung cancer, including those induced via intrapulmonary injection and intratracheal injection, have been r
Externí odkaz:
https://doaj.org/article/4b1edfdce95048dca8a58f380a2d1363
Autor:
Tsukasa Tominari, Masaru Takatoya, Toshiya Matsubara, Michio Matsunobe, Daichi Arai, Chiho Matsumoto, Michiko Hirata, Shosei Yoshinouchi, Chisato Miyaura, Yoshifumi Itoh, Hirofumi Komaki, Shin’ichi Takeda, Yoshitsugu Aoki, Masaki Inada
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 303 (2023)
Duchenne muscular dystrophy (DMD) is the most common type of neuromuscular disease caused by mutations in the DMD gene encoding dystrophin protein. To quantitively assess human dystrophin protein in muscle biopsy samples, it is imperative to consiste
Externí odkaz:
https://doaj.org/article/763e91c55e694f5ea2261661ed13a96c
Autor:
Yoshifumi Itoh
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Under normal conditions, the cellular microenvironment is optimized for the proper functioning of the tissues and organs. Cells recognize and communicate with the surrounding cells and extracellular matrix to maintain homeostasis. When cancer arises,
Externí odkaz:
https://doaj.org/article/850731f620e64a90b2a5eb2c7f684790
Autor:
Tsukasa Tominari, Ayumi Sanada, Ryota Ichimaru, Chiho Matsumoto, Michiko Hirata, Yoshifumi Itoh, Yukihiro Numabe, Chisato Miyaura, Masaki Inada
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Periodontitis is an inflammatory disease associated with severe alveolar bone loss and is dominantly induced by lipopolysaccharide from Gram-negative bacteria; however, the role of Gram-positive bacteria in periodontal bone resorption remain
Externí odkaz:
https://doaj.org/article/805e60ede4434cd0b11c984d4a9456d6
Autor:
Jennifer Vandooren, Yoshifumi Itoh
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Alpha-2-macroglobulin is an extracellular macromolecule mainly known for its role as a broad-spectrum protease inhibitor. By presenting itself as an optimal substrate for endopeptidases of all catalytic types, alpha-2-macroglobulin lures active prote
Externí odkaz:
https://doaj.org/article/088091b1d62a4248a10c01bc64d125b6
Autor:
Yoshifumi Itoh
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Multicellular organisms are composed of cells and extracellular matrix (ECM). ECM is a network of multidomain macromolecules that fills gaps between cells. It acts as a glue to connect cells, provides scaffolding for migrating cells, and pools cytoki
Externí odkaz:
https://doaj.org/article/dc736eb051a84d24a49e3aac52ca9d52
Autor:
Stephan Heeb, Yoshifumi Itoh, Takayuki Nishijyo, Ursula Schnider, Christoph Keel, Julie Wade, Ultan Walsh, Fergal O'Gara, Dieter Haas
Publikováno v:
Molecular Plant-Microbe Interactions, Vol 13, Iss 2, Pp 232-237 (2000)
The minimal replicon of the Pseudomonas plasmid pVS1 was genetically defined and combined with the Escherichia coli p15A replicon, to provide a series of new, oligocopy cloning vectors (5.3 to 8.3 kb). Recombinant plasmids derived from these vectors
Externí odkaz:
https://doaj.org/article/f88050c3ab0748eab7b2f75ed453f605
Autor:
Shosei Yoshinouchi, Kento Karouji, Tsukasa Tominari, Moe Sugasaki, Chiho Matsumoto, Chisato Miyaura, Michiko Hirata, Yoshifumi Itoh, Masaki Inada
Publikováno v:
Biochemical and Biophysical Research Communications. 644:40-48
Autor:
Valentina Gifford, Anna Woskowicz, Noriko Ito, Stefan Balint, B. Christopher Lagerholm, Michael L. Dustin, Yoshifumi Itoh
Publikováno v:
Matrix Biology. 107:1-23
MT1-MMP plays a crucial role in promoting the cellular invasion of cancer cells by degrading the extracellular matrix to create a path for migration. During this process, its localization at the leading edge of migrating cells is critical, and it is