Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Yoshifumi Hosono"'
Autor:
Masayuki Seki, Takuya Abe, Masamichi Ishiai, Takemi Enomoto, Minoru Takata, Hiroshi Arakawa, Weidong Wang, Yutaka Ishii, Shunichi Takeda, M. Nurul Islam, Yoshifumi Hosono
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1843(5):1002-1012
RecQ family DNA helicases function in the maintenance of genome stability. Mice deficient in RecQL5, one of five RecQ helicases, show a cancer predisposition phenotype, suggesting that RecQL5 plays a tumor suppressor role. RecQL5 interacts with Rad51
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::483cfebf99c7df5b34073dd146b93c3c
Autor:
Shusuke Tada, Takemi Enomoto, Masahiko Kobayashi, Motomu Akita, Takuya Abe, Masayuki Seki, Ken Ichi Yamamoto, Akari Yoshimura, Yoshifumi Hosono
Publikováno v:
Biochemical and Biophysical Research Communications. 414:298-303
Claspin was originally identified as a Check1 (Chk1)-interacting protein. Claspin and Rad17 are reportedly involved in the DNA damage-induced phosphorylation of Chk1, a hallmark of checkpoint activation. To understand the cellular functions of Claspi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c1e5fe64b24f4b6d77fc9b6d7c579ed
https://doi.org/10.1016/j.bbrc.2011.09.037
https://doi.org/10.1016/j.bbrc.2011.09.037
Autor:
Yasunari Takami, Takemi Enomoto, Akari Yoshimura, Motomu Akita, Masami Horikoshi, Shunichi Takeda, Katsuzumi Okumura, Tatsuo Nakayama, Shusuke Tada, Hiromu Murofushi, Masayuki Seki, Takuya Abe, Yoshifumi Hosono, Kazuto Sugimura
Publikováno v:
Journal of Biological Chemistry. 286:30504-30512
Ordered nucleosome disassembly and reassembly are required for eukaryotic DNA replication. The facilitates chromatin transcription (FACT) complex, a histone chaperone comprising Spt16 and SSRP1, is involved in DNA replication as well as transcription
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9a3b4f4e35e98abbaf6de0dc7fffb61
https://doi.org/10.1074/jbc.m111.264721
https://doi.org/10.1074/jbc.m111.264721
Publikováno v:
Biochemical and Biophysical Research Communications. 410:568-573
DNA double strand breaks (DSBs) induced by etoposide, an inhibitor of DNA topoisomerase II, are repaired mainly by non-homologous end joining (NHEJ). Unexpectedly, it was found that at high doses of etoposide, proteins involved in NHEJ, such as KU70/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adfb783307f66f288e91351c98dda2c1
https://doi.org/10.1016/j.bbrc.2011.06.027
https://doi.org/10.1016/j.bbrc.2011.06.027
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1813(3):473-479
Rothmund-Thomson syndrome (RTS) is a rare genetic disorder characterized by premature aging, developmental abnormalities, and a predisposition to cancer. RTS is caused by mutations in the RECQL4 gene, which encodes one of the five human RecQ helicase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89d1e2b87f591b5c9b7430c7856ce4a8
Autor:
Hideki Koyama, Shunichi Takeda, Shusuke Tada, Takemi Enomoto, Masamichi Ishiai, Yoshifumi Hosono, Minoru Takata, Akari Yoshimura, Takuya Abe, Masayuki Seki, Noritaka Adachi
Publikováno v:
Cellular Signalling. 20:1978-1985
KU70(-/-) and DNA-PKcs(-/-/-)chicken DT40 cells are reportedly highly sensitive to the DNA topoisomerase II inhibitor etoposide. Here we report that KU70 and DNA-PKcs unexpectedly function together during the induction of apoptosis after exposure to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c90128d68ea471ab0439673ea8766c4
https://doi.org/10.1016/j.cellsig.2008.07.006
https://doi.org/10.1016/j.cellsig.2008.07.006
Autor:
Kosa Kajii, Masayuki Seki, Takuya Abe, Shusuke Tada, Yoshifumi Hosono, Shuichi Sakuraba, Takemi Enomoto, Masato Higuchi
Publikováno v:
The Journal of biological chemistry. 289(16)
The replication fork temporarily stalls when encountering an obstacle on the DNA, and replication resumes after the barrier is removed. Simultaneously, activation of the replication checkpoint delays the progression of S phase and inhibits late origi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb5cd1dbd17cb89bf82916ca036e2dc3
https://pubmed.ncbi.nlm.nih.gov/24573676
https://pubmed.ncbi.nlm.nih.gov/24573676
Autor:
Takuya, Abe, Akari, Yoshimura, Yoshifumi, Hosono, Shusuke, Tada, Masayuki, Seki, Takemi, Enomoto
Publikováno v:
Biochimica et biophysica acta. 1813(3)
Rothmund-Thomson syndrome (RTS) is a rare genetic disorder characterized by premature aging, developmental abnormalities, and a predisposition to cancer. RTS is caused by mutations in the RECQL4 gene, which encodes one of the five human RecQ helicase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ec6317dbd579a3a48e13941c407b7443
https://pubmed.ncbi.nlm.nih.gov/21256165
https://pubmed.ncbi.nlm.nih.gov/21256165
Autor:
Yoshifumi Hosono1, Takuya Abe2, Masato Higuchi1, Kajii, Kosa3, Shuichi Sakuraba1, Shusuke Tada4, Takemi Enomoto5, Masayuki Seki3 seki@tohoku-pharm.ac.jp
Publikováno v:
Journal of Biological Chemistry. 4/18/2014, Vol. 289 Issue 16, p11374-11384. 11p.