Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Yoshifumi, SATO"'
Autor:
Tatsuya Yoshizawa, Yoshifumi Sato, Shihab U. Sobuz, Tomoya Mizumoto, Tomonori Tsuyama, Md. Fazlul Karim, Keishi Miyata, Masayoshi Tasaki, Masaya Yamazaki, Yuichi Kariba, Norie Araki, Eiichi Araki, Shingo Kajimura, Yuichi Oike, Thomas Braun, Eva Bober, Johan Auwerx, Kazuya Yamagata
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Sirtuins have been reported to positively regulate brown adipose tissue thermogenesis. Here the authors report that brown adipocytic SIRT7 suppresses whole-body energy expenditure and thermogenesis in mice, potentially by attenuating batokine gene ex
Externí odkaz:
https://doaj.org/article/7b51c06d17574f72b35f0b3884a3c7fe
Autor:
Masaji Sakaguchi, Shota Okagawa, Yuma Okubo, Yuri Otsuka, Kazuki Fukuda, Motoyuki Igata, Tatsuya Kondo, Yoshifumi Sato, Tatsuya Yoshizawa, Takaichi Fukuda, Kazuya Yamagata, Weikang Cai, Yu-Hua Tseng, Nobuo Sakaguchi, C. Ronald Kahn, Eiichi Araki
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
The insulin signalling cascade can be inhibited by phosphatases, including Ser/Thr protein phosphatase 2A (PP2A). Here the authors show that Alpha4, a regulator of the PP2A catalytic subunit, modulates insulin receptor tyrosine phosphorylation via th
Externí odkaz:
https://doaj.org/article/5e9e60d829fc411da353c7feb24250ca
Autor:
Tomoya Mizumoto, Tatsuya Yoshizawa, Yoshifumi Sato, Takaaki Ito, Tomonori Tsuyama, Akiko Satoh, Satoshi Araki, Kenichi Tsujita, Masaru Tamura, Yuichi Oike, Kazuya Yamagata
Publikováno v:
Cells, Vol 11, Iss 22, p 3609 (2022)
Sirtuins (SIRT1–7 in mammals) are evolutionarily conserved nicotinamide adenine dinucleotide-dependent lysine deacetylases/deacylases that regulate fundamental biological processes including aging. In this study, we reveal that male Sirt7 knockout
Externí odkaz:
https://doaj.org/article/9b674fd2c8d0417291226fbd941a0840
Autor:
Masatoshi Fukuda, Tatsuya Yoshizawa, Md. Fazlul Karim, Shihab U. Sobuz, Wataru Korogi, Daiki Kobayasi, Hiroki Okanishi, Masayoshi Tasaki, Katsuhiko Ono, Tomohiro Sawa, Yoshifumi Sato, Mami Chirifu, Takeshi Masuda, Teruya Nakamura, Hironori Tanoue, Kazuhisa Nakashima, Yoshihiro Kobashigawa, Hiroshi Morioka, Eva Bober, Sumio Ohtsuki, Yuriko Yamagata, Yukio Ando, Yuichi Oike, Norie Araki, Shu Takeda, Hiroshi Mizuta, Kazuya Yamagata
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
SP7/Osterix is a transcription factor involved in osteoblast differentiation. Here, the authors show that Sirtuin 7 activates Osterix posttranslationally by regulating its lysine acylation, and that mice lacking Sirtuin 7 in osteoblasts show reduced
Externí odkaz:
https://doaj.org/article/5d154c78ddfa43f09911b245d2d21134
Publikováno v:
Journal of Research in Science Education. 62:261-273
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a3bd769300fb8561dabf4b497072ec0
https://doi.org/10.11639/sjst.20025
https://doi.org/10.11639/sjst.20025
Autor:
Hironori Mizutani, Yoshifumi Sato, Masaya Yamazaki, Tatsuya Yoshizawa, Yukio Ando, Mitsuharu Ueda, Kazuya Yamagata
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 16; Pages: 9027
Alzheimer’s disease (AD) is an age-related neurodegenerative disease that is characterized by irreversible memory loss and cognitive decline. The deposition of amyloid-β (Aβ), especially aggregation-prone Aβ42, is considered to be an early event
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ef7500022bd91dda61158220e6d5026
Publikováno v:
上越教育大学教職大学院研究紀要 = Bulletin of Teaching Profession Graduate School Joetsu University of Education. 8:55-61
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=jairo_______::791da62a3aa458e429a2fa65f50877e3
http://hdl.handle.net/10513/00008336
http://hdl.handle.net/10513/00008336
Autor:
Yumiko Kawamura, Yasuhiro Izumiya, Mitsuyoshi Nakao, Yasuhito Tanaka, Yoshifumi Sato, Kazuya Yamagata, Toshihiro Yamada, Kazuo Tonami, Takashi Yamamoto, Terumasa Umemoto, Naomi Nakagata, Toru Takeo, Shinjiro Hino, Kenichi Matsushita, Yoshiko Nakagawa, Toshio Suda, Sanshiro Hanada, Taishi Nakamura, Kenji Sakamoto, Takehisa Watanabe, Yuichiro Arima, Katsuya Nagaoka, Eiichiro Yamamoto, Hiroki Kurihara, Koichi Nishiyama, Koichi Kaikita, Kenichi Tsujita, Tetsushi Sakuma, Toshifumi Ishida, Satoshi Araki
Publikováno v:
Nature Metabolism. 3:196-210
Ketone bodies are generated in the liver and allow for the maintenance of systemic caloric and energy homeostasis during fasting and caloric restriction. It has previously been demonstrated that neonatal ketogenesis is activated independently of star
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7375e89380de6d74936cb06e3e4557dd
https://doi.org/10.1038/s42255-021-00342-6
https://doi.org/10.1038/s42255-021-00342-6
Hypoxia can occur in pancreatic β-cells in type 2 diabetes. Although hypoxia exerts deleterious effects on β-cell function, the associated mechanisms are largely unknown. Here, we show that the transcriptional repressor basic helix-loop-helix famil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c217c3ee2b09d63e3598c218c247d92e
https://doi.org/10.1101/2022.06.28.498031
https://doi.org/10.1101/2022.06.28.498031
