Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Yoshie Umehara"'
Autor:
Ge Peng, Saya Tsukamoto, Risa Ikutama, Hai Le Thanh Nguyen, Yoshie Umehara, Juan V. Trujillo-Paez, Hainan Yue, Miho Takahashi, Takasuke Ogawa, Ryoma Kishi, Mitsutoshi Tominaga, Kenji Takamori, Jiro Kitaura, Shun Kageyama, Masaaki Komatsu, Ko Okumura, Hideoki Ogawa, Shigaku Ikeda, François Niyonsaba
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 17 (2022)
Human β-defensin-3 (hBD-3) exhibits antimicrobial and immunomodulatory activities; however, its contribution to autophagy regulation remains unclear, and the role of autophagy in the regulation of the epidermal barrier in atopic dermatitis (AD) is p
Externí odkaz:
https://doaj.org/article/730aa69b1d874b99b25b902f4ecf9b79
Autor:
Miho Takahashi, Yoshie Umehara, Hainan Yue, Juan Valentin Trujillo-Paez, Ge Peng, Hai Le Thanh Nguyen, Risa Ikutama, Ko Okumura, Hideoki Ogawa, Shigaku Ikeda, François Niyonsaba
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
In addition to its antimicrobial activity, the skin-derived antimicrobial peptide human β-defensin-3 (hBD-3) promotes keratinocyte proliferation and migration to initiate the wound healing process; however, its effects on fibroblasts, which are the
Externí odkaz:
https://doaj.org/article/553ee22d19d44e0a86146599a9b1cd01
Autor:
Yasuko Yoshioka, Yayoi Kamata, Mitsutoshi Tominaga, Yoshie Umehara, Ikuyo Yoshida, Nobuya Matsuoka, Kenji Takamori
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0250663 (2021)
In a disease-state-dependent manner, the histamine-resistant itch in dry skin-based skin diseases such as atopic dermatitis (AD) and xerosis is mainly due to hyperinnervation in the epidermis. Semaphorin 3A (Sema3A) is a nerve repulsion factor expres
Externí odkaz:
https://doaj.org/article/83e8292f3e584081a3d664922014ef0d
Autor:
Nobuaki Takahashi, Mitsutoshi Tominaga, Ryohei Kosaka, Yayoi Kamata, Yoshie Umehara, Hironori Matsuda, Azumi Sakaguchi, Hideoki Ogawa, Kenji Takamori
Publikováno v:
Acta Dermato-Venereologica, Vol 97, Iss 8, Pp 928-933 (2017)
The pathogenesis of psoriatic itch is poorly understood. The aim of this study was to investigate the involvement of opioid receptors in scratching behaviour of imiquimod-induced psoriasis-like dermatitis model mice. Topical application of 5% imiquim
Externí odkaz:
https://doaj.org/article/21817a7fdc6348d897c358270c1afa82
Autor:
Yoshie Umehara, Chanisa Kiatsurayanon, Juan Valentin Trujillo-Paez, Panjit Chieosilapatham, Ge Peng, Hainan Yue, Hai Le Thanh Nguyen, Pu Song, Ko Okumura, Hideoki Ogawa, François Niyonsaba
Publikováno v:
Biomedicines, Vol 9, Iss 3, p 229 (2021)
Itch or pruritus is the hallmark of atopic dermatitis and is defined as an unpleasant sensation that evokes the desire to scratch. It is also believed that itch is a signal of danger from various environmental factors or physiological abnormalities.
Externí odkaz:
https://doaj.org/article/b6fc7c7c0d5e4e29a403cc296bf63a04
Autor:
Hai Le Thanh Nguyen, Ge Peng, Juan Valentin Trujillo-Paez, Hainan Yue, Risa Ikutama, Miho Takahashi, Yoshie Umehara, Ko Okumura, Hideoki Ogawa, Shigaku Ikeda, François Niyonsaba
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 6; Pages: 5200
The antimicrobial peptide derived from insulin-like growth factor-binding protein 5 (AMP-IBP5) exhibits antimicrobial activities and immunomodulatory functions in keratinocytes and fibroblasts. However, its role in regulating skin barrier function re
Autor:
Hainan Yue, Pu Song, Nutda Sutthammikorn, Yoshie Umehara, Juan Valentin Trujillo‐Paez, Hai Le Thanh Nguyen, Miho Takahashi, Ge Peng, Risa Ikutama, Ko Okumura, Hideoki Ogawa, Shigaku Ikeda, François Niyonsaba
Publikováno v:
Wound Repair and Regeneration. 30:232-244
Impaired keratinocyte functions are major factors that are responsible for delayed diabetic wound healing. In addition to its antimicrobial activity, the antimicrobial peptide derived from insulin-like growth factor-binding protein 5 (AMP-IBP5) activ
Autor:
Yoshie Umehara, Juan Valentin Trujillo-Paez, Hainan Yue, Ge Peng, Hai Le Thanh Nguyen, Ko Okumura, Hideoki Ogawa, François Niyonsaba
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 11; Pages: 9347
Atopic dermatitis and psoriasis are prevalent chronic inflammatory skin diseases that are characterized by dysfunctional skin barriers and substantially impact patients’ quality of life. Vitamin D3 regulates immune responses and keratinocyte differ