Výsledky vyhledávání - "Yoshie Tsubotani"

Bactericidal Effects and Mechanism of Action of Olanexidine Gluconate, a New Antiseptic

Autor: Koushi Iwata, Takuya Nii, Hikaru Nakata, Yasuhide Inoue, Akifumi Hagi, Yoshie Tsubotani

Publikováno v: Antimicrobial Agents and Chemotherapy. 59:4551-4559

Olanexidine gluconate [1-(3,4-dichlorobenzyl)-5-octylbiguanide gluconate] (development code OPB-2045G) is a new monobiguanide compound with bactericidal activity. In this study, we assessed its spectrum of bactericidal activity and mechanism of actio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::835500c7b0233007a6e29aaa5f83ecd9
https://doi.org/10.1128/aac.05048-14

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Effects of olanexidine gluconate on preoperative skin preparation: an experimental study in cynomolgus monkeys

Autor: Yasuhide Inoue, Tadashi Imamura, Hikaru Nakata, Akifumi Hagi, Takuya Nii, Yoshie Tsubotani

Publikováno v: Journal of Medical Microbiology

Purpose. To determine the bactericidal efficacy of a new topical antiseptic for preoperative skin preparation, olanexidine gluconate (development code: OPB-2045G), against transient or resident bacterial flora on the skin of cynomolgus monkeys. Metho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56fff5bc51e6d15649a26f767db3a24f
https://pubmed.ncbi.nlm.nih.gov/28516852

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Novel antiseptic compound OPB-2045G shows potent bactericidal activity against methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus both in vitro and in vivo: a pilot study in animals

Autor: Yasuhide Inoue, Yoshie Tsubotani, Hikaru Nakata, Koushi Iwata, Akifumi Hagi, Takuya Nii

Publikováno v: Journal of medical microbiology. 64(Pt 1)

There is a need for new compounds to effectively treat methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE). The novel monobiguanide compound 1-(3,4-dichlorobenzyl)-5-octylbiguanide gluconate (OPB-2045G) has

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca77e7cd8e4abaedf3cfbb0714db27fb
https://pubmed.ncbi.nlm.nih.gov/25351713

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Dysideamine, a new sesquiterpene aminoquinone, protects hippocampal neuronal cells against iodoacetic acid-induced cell death

Autor: Hideaki Suna, Yoshie Tsubotani, Asami Hayashi, Andi Setiawan, Masayoshi Arai, Motomasa Kobayashi

Publikováno v: Bioorganicmedicinal chemistry. 17(11)

In the course of our search for neuroprotective agents, dysideamine (1), a new sesquiterpene aminoquinone, was isolated along with bolinaquinone (2) from Indonesian marine sponge of Dysidea sp. Compounds 1 and 2 showed neuroprotective effect against

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7a40878e7521864a538ca3c5f0bfbb9
https://pubmed.ncbi.nlm.nih.gov/19414266

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