Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Yoshie Sanayama"'
Autor:
Kensuke Suga, Akira Suto, Shigeru Tanaka, Yutaka Sugawara, Takahiro Kageyama, Junichi Ishikawa, Yoshie Sanayama, Kei Ikeda, Shunsuke Furuta, Shin-Ichiro Kagami, Arifumi Iwata, Koichi Hirose, Kotaro Suzuki, Osamu Ohara, Hiroshi Nakajima
Publikováno v:
JCI Insight, Vol 8, Iss 10 (2023)
Methotrexate (MTX) is a standard, first-line therapy for rheumatoid arthritis (RA); however, its precise mechanisms of action other than antifolate activity are largely unknown. We performed DNA microarray analyses of CD4+ T cells in patients with RA
Externí odkaz:
https://doaj.org/article/8f9f04e72ce6453796321fc070a9ae6d
Autor:
Kei Ikeda, Taro Iwamoto, Shunsuke Furuta, Junichi Nakamura, Takeshi Umibe, Masaki Hiraguri, Hiroshi Nakajima, Shin-ichiro Kagami, Yoshihisa Kobayashi, Hirotoshi Kawashima, Ayako Matsuki, Seiji Ohtori, Masashi Fukuta, Daiki Nakagomi, Norihiro Mimura, Takayuki Nakamura, Aiko Saku, Kentaro Takahashi, Yoshie Sanayama, Toyohiko Sugimoto, Koichi Hirose, Hiroaki Takatori, Kenichi Suehiro, Shigekazu Takahashi, Tomohiro Tamachi, Manami Kato, Fumiyoshi Takizawa, Yuya Kawarai, Shigeo Hagiwara
Publikováno v:
RMD Open, Vol 9, Iss 1 (2023)
Objective We aimed to determine the prevalence and risk factors for osteonecrosis of the femoral head (ONFH) in a multicentre cohort of patients with antineutrophil cytoplasmic antibody-associated vasculitis (AAV).Methods One hundred and eighty-six A
Externí odkaz:
https://doaj.org/article/0ad3c7cc22724128ab189f6ede6902ef
Autor:
Kei Ikeda, Yoshie Sanayama, Sohei Makita, Junichi Hosokawa, Mieko Yamagata, Daiki Nakagomi, Katsuhiko Takabayashi, Hiroshi Nakajima
Publikováno v:
Clinical and Developmental Immunology, Vol 2013 (2013)
Introduction. This study aimed to investigate the efficacy of abatacept for arthritis in patients with rhupus, an overlap syndrome between rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). Methods. Patients who fulfilled both the 2010
Externí odkaz:
https://doaj.org/article/e5e13363edb74fa9a2dfd4cf48c7585b
Autor:
Norihiro Mimura, Taro Iwamoto, Shunsuke Furuta, Kei Ikeda, Yoshihisa Kobayashi, Takayuki Nakamura, Aiko Saku, Shin-Ichiro Kagami, Ayako Matsuki, Kentaro Takahashi, Takeshi Umibe, Daiki Nakagomi, Yoshie Sanayama, Toyohiko Sugimoto, Masashi Fukuta, Masaki Hiraguri, Hirotoshi Kawashima, Koichi Hirose, Hiroaki Takatori, Kenichi Suehiro, Shigekazu Takahashi, Tomohiro Tamachi, Manami Kato, Fumiyoshi Takizawa, Yuya Kawarai, Shigeo Hagiwara, Junichi Nakamura, Seiji Ohtori, Hiroshi Nakajima
Publikováno v:
RMD Open. 9:e002787
ObjectiveWe aimed to determine the prevalence and risk factors for osteonecrosis of the femoral head (ONFH) in a multicentre cohort of patients with antineutrophil cytoplasmic antibody-associated vasculitis (AAV).MethodsOne hundred and eighty-six AAV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da77df5c245574dc96412e2f5d8808c1
https://doi.org/10.1136/rmdopen-2022-002787
https://doi.org/10.1136/rmdopen-2022-002787
Autor:
Kazuyuki Meguro, Osamu Ohara, Akira Suto, Kotaro Suzuki, Shigeru Tanaka, Shunsuke Furuta, Hiroshi Nakajima, Kei Ikeda, Akemi Sakamoto, Hiroaki Takatori, Junichi Hosokawa, Yoshie Sanayama
Publikováno v:
Arthritis & Rheumatology. 67:2651-2660
Objective We have previously shown that expression of the Bcl-3 gene, a member of the IκB family, is down-regulated in CD4+ T cells from patients with rheumatoid arthritis (RA) following tocilizumab therapy. The objective of this study was to examin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4fddb53ff0bb0c3bea4e0529bcfb85b
https://doi.org/10.1002/art.39266
https://doi.org/10.1002/art.39266
Autor:
Shohei Hori, Hiroshi Nakajima, Shigeru Tanaka, Taro Iwamoto, Yoshie Sanayama, Kei Ikeda, Akira Suto, Koichi Hirose, Kazuyuki Meguro, Shin Ichiro Kagami, Tomohiro Tamachi, Kotaro Suzuki, Ayako Matsuki, Natsuko Nishikawa, Hirotoshi Kawashima, Hiroaki Takatori, Masato Kubo
Publikováno v:
Arthritis & Rheumatology. 67:1491-1502
Objective Helios+FoxP3+CD4+ (Helios+) Treg cells are believed to be involved in the regulation of various autoimmune diseases; however, the regulatory mechanisms underlying the development of Helios+ Treg cells remain uncertain. This study was undert
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03a45363ca8edcc48a726041745d6c4b
https://doi.org/10.1002/art.39091
https://doi.org/10.1002/art.39091
Autor:
Daisuke Kashiwakuma, Ryutaro Matsumura, Takao Sugiyama, Itsuo Iwamoto, Osamu Ohara, Mieko Yamagata, Makoto Sueishi, Masaki Hiraguri, Kei Ikeda, Takeshi Umibe, Hiroshi Nakajima, Yoshie Sanayama, Shunsuke Furuta, Shin-ichiro Kagami, Nawata Y, Yukari Saito, Ken Nonaka
Publikováno v:
Arthritis & Rheumatology. 66:1421-1431
Objective The aim of this prospective multicenter study was to identify biomarkers that can be used to predict therapeutic responses to tocilizumab in patients with rheumatoid arthritis (RA). Methods We recruited patients with RA who were treated wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d602e9abfe2b2853fc9c58d49498ad8d
https://doi.org/10.1002/art.38400
https://doi.org/10.1002/art.38400
Autor:
Daisuke Kashiwakuma, Ken Nonaka, Akira Suto, Shin-ichiro Kagami, Itsuo Iwamoto, Kei Ikeda, Osamu Ohara, Shunsuke Furuta, Yukari Saito, Yoshie Sanayama, Hiroshi Nakajima
Publikováno v:
Arthritis & Rheumatology. 66:1185-1194
Objective The proinflammatory cytokines tumor necrosis factor α and interleukin-6 (IL-6) and the Th17 cell cytokine IL-17A are implicated in the pathogenesis of rheumatoid arthritis (RA), and the blockade of these cytokines by biologic agents provid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b0150235ad2c50abc81481f8596c33a
https://doi.org/10.1002/art.38324
https://doi.org/10.1002/art.38324
Autor:
Hiroyuki Matsue, Daisuke Kashiwakuma, Kotaro Suzuki, Ryutaro Matsumura, Daiki Nakagomi, Taro Iwamoto, Yoshie Sanayama, Shigeru Tanaka, Naotomo Kambe, Itsuo Iwamoto, Akira Suto, Kei Ikeda, Hiroshi Nakajima
Publikováno v:
Rheumatology. 52:1963-1972
Objective. Although several miRNAs have been shown to regulate autoimmune pathogenesis by affecting lymphocyte function, the roles of miRNAs in the pathogenesis of SSc remain unclear. Therefore the purpose of this study was to identify miRNAs that pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4ca66d7b8288b60015ffe36314df889
https://doi.org/10.1093/rheumatology/ket254
https://doi.org/10.1093/rheumatology/ket254
Autor:
Mieko Yamagata, Katsuhiko Takabayashi, Hiroaki Takatori, Daiki Nakagomi, Hiroshi Nakajima, Taro Iwamoto, Kentaro Takahashi, Yoshie Sanayama, Kotaro Suzuki, Ayako Okubo, Kei Ikeda
Publikováno v:
Arthritis & Rheumatism. 65:890-898
Objective The 2010 American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) classification criteria for rheumatoid arthritis (RA) refer to a possible use of ultrasound “for confirmation of the clinical findings.” We underto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e98ad69d396f11b502fd43e7256666a
https://doi.org/10.1002/art.37848
https://doi.org/10.1002/art.37848