Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Yoshie SUGIURA"'
Publikováno v:
PLoS Genetics, Vol 15, Iss 3, p e1007857 (2019)
Schwann cells are integral components of vertebrate neuromuscular synapses; in their absence, pre-synaptic nerve terminals withdraw from post-synaptic muscles, leading to muscle denervation and synapse loss at the developing neuromuscular junction (N
Externí odkaz:
https://doaj.org/article/ebd71f84e9634c14a6ccc2db407af491
Autor:
Hong Y Choi, Yun Liu, Christian Tennert, Yoshie Sugiura, Andromachi Karakatsani, Stephan Kröger, Eric B Johnson, Robert E Hammer, Weichun Lin, Joachim Herz
Publikováno v:
eLife, Vol 2 (2013)
ApoE, ApoE receptors and APP cooperate in the pathogenesis of Alzheimer’s disease. Intriguingly, the ApoE receptor LRP4 and APP are also required for normal formation and function of the neuromuscular junction (NMJ). In this study, we show that APP
Externí odkaz:
https://doaj.org/article/729afe712e7f427d8571088a9a1ccb06
Publikováno v:
The Journal of Neuroscience. 39:6049-6066
Synaptic transmission occurs when an action potential triggers neurotransmitter release via the fusion of synaptic vesicles with the pre-synaptic membrane, driven by the formation of SNARE complexes composed of the vesicular (v)-SNARE synaptobrevin a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41598b3ab2bc344ad7c60f7ef165c21f
https://doi.org/10.1523/jneurosci.0403-19.2019
https://doi.org/10.1523/jneurosci.0403-19.2019
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 15, Iss 3, p e1007857 (2019)
PLoS Genetics, Vol 15, Iss 3, p e1007857 (2019)
Schwann cells are integral components of vertebrate neuromuscular synapses; in their absence, pre-synaptic nerve terminals withdraw from post-synaptic muscles, leading to muscle denervation and synapse loss at the developing neuromuscular junction (N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e0d5535e7d9c06460b74a9004cc1558
https://pubmed.ncbi.nlm.nih.gov/30870432
https://pubmed.ncbi.nlm.nih.gov/30870432
Autor:
Yun Liu, Wentao Mi, Thomas L. Carroll, Yoshie Sugiura, Weichun Lin, Fenfen Wu, Steve C. Cannon, Makoto Mark Taketo
Publikováno v:
Developmental Biology. 366:255-267
β-Catenin, a key component of the Wnt signaling pathway, has been implicated in the development of the neuromuscular junction (NMJ) in mice, but its precise role in this process remains unclear. Here we use a β-catenin gain-of-function mouse model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3312046cacfb0697874818636173bbb1
https://doi.org/10.1016/j.ydbio.2012.04.003
https://doi.org/10.1016/j.ydbio.2012.04.003
Publikováno v:
The Journal of Physiology. 589:1603-1618
Synaptobrevin (Syb)/vesicle-associated membrane protein (VAMP) is a small, integral membrane protein of synaptic vesicles. Two homologous isoforms of synaptobrevin, Syb1/VAMP1 and Syb2/VAMP2, exhibit distinct but partially overlapping patterns of exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::952399ef5c58a1527b337f4e40f8c1cf
https://doi.org/10.1113/jphysiol.2010.201939
https://doi.org/10.1113/jphysiol.2010.201939
Neuromuscular synaptic patterning requires the function of skeletal muscle dihydropyridine receptors
Publikováno v:
Nature neuroscience
Developing skeletal myofibers in vertebrates are intrinsically “pre-patterned” for motor nerve innervation. However, the intrinsic factors that regulate muscle pre-patterning remain unknown. Here we show that a functional skeletal muscle dihydrop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48b2c26560cf25f3b0a488f3aa717745
http://europepmc.org/articles/PMC3083454
http://europepmc.org/articles/PMC3083454
Autor:
Bertha Dominguez, Brian K. Kaspar, Ronald W. Oppenheim, Yoshie Sugiura, Prafulla Aryal, Thomas W. Gould, Weichun Lin, Kuo-Fen Lee, Mark E. Hester, Mahru C. An, Chien-Ping Ko, Jiefei Yang, Daniel Padgett
Publikováno v:
Proceedings of the National Academy of Sciences. 107:10702-10707
Emerging evidence suggests that the neurotransmitter acetylcholine (ACh) negatively regulates the development of the neuromuscular junction, but it is not clear if ACh exerts its effects exclusively through muscle ACh receptors (AChRs). Here, we used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30d023bc044f798223aa06b0818dac9b
https://doi.org/10.1073/pnas.1004956107
https://doi.org/10.1073/pnas.1004956107
Publikováno v:
Journal of Molecular Neuroscience. 40:21-26
The mammalian muscle nicotinic acetylcholine receptor (AChR) is composed of five membrane-spanning subunits and its composition differs between embryonic and adult muscles. In embryonic muscles, it is composed of two alpha-, one beta-, one delta-, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06fc15ebe2578e08630f821631816d1e
https://doi.org/10.1007/s12031-009-9248-x
https://doi.org/10.1007/s12031-009-9248-x
Publikováno v:
Developmental Biology. 330:153-166
Nedd4 (neural precursor cell expressed developmentally down-regulated gene 4) is an E3 ubiquitin ligase highly conserved from yeast to humans. The expression of Nedd4 is developmentally down-regulated in the mammalian nervous system, but the role of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03d3b548ecb7aa9b999764d5b75f9823
https://doi.org/10.1016/j.ydbio.2009.03.023
https://doi.org/10.1016/j.ydbio.2009.03.023