Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Yoshiaki Takashima"'
Autor:
Yuki Iwayanagi, Kunihiro Hattori, Etsuko Fujii, Yoshiaki Takashima, Keiko Kasutani, Sohei Oyama, Masahiko Nanami, Hideki Adachi, Yoshiki Kawabe, Hidetomo Kitamura, Hiroaki Matsushita, Keiko Esaki, Akihisa Sakamoto, Tsukasa Suzuki, Taichi Kuramochi, Shin Shimaoka, Akihisa Kaneko, Masaaki Goto, Yoshinobu Higuchi
Publikováno v:
Experimental Dermatology. 27:14-21
Scratching is an important factor exacerbating skin lesions through the so-called itch-scratch cycle in atopic dermatitis (AD). In mice, interleukin (IL)-31 and its receptor IL-31 receptor A (IL-31RA) are known to play a critical role in pruritus and
Autor:
Hiroaki Matsushita, Akimichi Morita, Etsuko Fujii, Yoshiaki Takashima, Atsuhiko Kato, Takeshi Watanabe, Takuya Furuhashi
Publikováno v:
Journal of Dermatological Science. 74:229-235
Background To understand the clinical segments of IL-31 signaling blockade therapy in pruritus of atopic dermatitis (AD), direct detection of the target proteins in the diseased tissues will provide crucial information. There is a lack of direct evid
Autor:
Etsuo Niki, Tatsuhiko Kodama, Mitsutaka Yoshida, Yoshiaki Takashima, Osamu Cynshi, Yoshiki Kawabe, Yoshiaki Kato, Tsukasa Suzuki, Motomu Himori, Makoto Shimizu, Akira Ishikawa, Yasuharu Kato, Kunio Tamura
Publikováno v:
Journal of Medicinal Chemistry. 46:3083-3093
Antioxidants have been considered as potential antiatherogenic agents by inhibiting oxidation of low-density lipoprotein (LDL), albeit vitamin E, a natural antioxidant, has failed to show reduction on atherosclerosis in clinical trials. We have ratio
Autor:
Ikurou Umezu, Akira Sugimura, Naomichi Sakamoto, Yoshiaki Takashima, Takatoshi Murota, Ken-ichi Yoshida, Mitsuru Inada
Publikováno v:
Journal of Applied Physics. 91:2009-2013
We prepared hydrogen and oxygen alloys of a-Si by the method of rf sputtering and found similarities in their photoluminescence (PL) features. Depression of PL intensity at high temperature is reduced by alloying and results in a larger PL intensity
Autor:
Etsuo Niki, Tatsuhiko Kodama, Akira Hayasaka, Yoshiki Kawabe, M. Nakamura, Yasuhiro Ohba, Hiroshi Kaise, Atsuko Higashida, Kunio Tamura, Hisashi Sakaguchi, Tsukasa Suzuki, Yoshiaki Takashima, Noriko Noguchi, Yoshiaki Kato, Kenji Inoue, Osamu Cynshi, Motohiro Takeya, Kiyoshi Takahashi
Publikováno v:
Proceedings of the National Academy of Sciences. 95:10123-10128
Antioxidants have been proposed to have antiatherogenic potential by their inhibition of low density lipoprotein (LDL) oxidation. Here, we report an antioxidant, BO-653 (2,3-dihydro-5-hydroxy-2,2-dipentyl-4,6-di- tert- butylbenzofuran), designed to e
Autor:
Yoshiaki Takashima
Publikováno v:
Burns. 23:591-595
Unbelievable decrease of blood-platelet in the severely burned patients during the treatment of skingrafting caused two patients to unexpected death. From the records of changes of platelet number, a certain ‘platelet curve’ was made. By observin
Autor:
Motoyukl Kataoka, Sadahiro Azuma, Youichiro Wada, Seikoh Horiuchi, Yutaka Toyoda, Yoshiaki Takashima, Tsukasa Suzuki, Shun Ishibashi, Tatsuhiko Kodama, Hiroki Kurihara, Hiroyuki Aburatani, Takefumi Doi, Osamu Cynshi, J. Kar Kruijt, Kou-ichi Jishage, Otoya Ueda, Yoshiki Kawabe, Yukiko Kurihara, Theo J.C. Van Berkel, Yoshio Yazaki, Hiroshi Suzuki, Hiroshige Itakura, Nobuyo Maeda, Motohiro Takeya, Hisashl Sakaguchi, Urs P. Steinbrecher, Tetsuo Noda, Kiyoshi Takahashi, Akiyo Matsumoto, Siamon Gordon, Makoto Honda, Takayuki Higashi, Nobuo Kamada
Publikováno v:
Nature. 386:292-296
Macrophage type-I and type-II class-A scavenger receptors (MSR-A) are implicated in the pathological deposition of cholesterol during atherogenesis as a result of receptor-mediated uptake of modified low-density lipoproteins (mLDL)1–6. MSR-A can bi
Autor:
Akiyo Matsumoto, Masahiro Nishijima, Kou-ichi Jishage, Tsukasa Suzuki, Hiroki Kurihara, Toru Miyazaki, Kiyoshi Takahashi, Tatuhiko Kodama, Yoshiaki Takashima, Yoshio Yazaki, Motoyuki Kataoka, Yukiko Kurihara, Motohiro Takeya, Takayuki Higashi, Otoya Ueda, Hiroshige Itakura, Youichiro Wada, Takefumi Doi, Osamu Cynshi, Makoto Honda, Nobuo Kamada, Seikou Hiriuchi, Tetsuo Noda, Hiroshi Suzuki
Publikováno v:
The Journal of Japan Atherosclerosis Society. 24:173-179
Publikováno v:
Journal of Bioluminescence and Chemiluminescence. 10:261-269
The action of phenolic antioxidants, such as probucol, on various active oxygen species was investigated using luminol chemiluminescence and spin trapping with 5,5-dimethyl-1-pyrroline-N-oxide (DMPO). The various active oxygen species, including hydr
Autor:
Tatsuhiko Kodama, Osamu Cynshi, Yoshiki Kawabe, Yoshiaki Takashima, Tsukasa Suzuki, Yasuhiro Ohba
Publikováno v:
Journal of Atherosclerosis and Thrombosis. 1:87-97
Oxidation of low density lipoproteins (LDL) has been shown to lead to enhanced uptake by macrophages mediated by the scavenger receptor. In the present study, changes in LDL induced by copper-catalyzed oxidation were investigated using gel permeation