Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Yoshiaki Fujinami"'
Publikováno v:
Journal of Pharmacological Sciences, Vol 118, Iss 3, Pp 363-372 (2012)
Many stimuli such as ischemia, hypoxia, heat shock, amino acid starvation, and gene mutation, exhibit a cellular response called endoplasmic reticulum (ER) stress. ER stress induces expression of a series of genes, leading to cell survival or apoptos
Externí odkaz:
https://doaj.org/article/89dea0977fd14c3abecc718111e526f2
Publikováno v:
International Journal of Medical Sciences
Trigeminal neuropathic pain is a facial pain syndrome associated with trigeminal nerve injury. However, the mechanism of trigeminal neuropathic pain is poorly understood. This study aimed to determine the role of transient receptor potential vanilloi
Publikováno v:
Pharmacology & Pharmacy. :427-432
Background: Among anti-hypertension drugs, calcium (Ca2+) antagonists cause gingival overgrowth as a side effect. We previously discovered that this side effect was due to elevation of the calcium concentration in the cytosol ([Ca2+]i). Ca2+ entry th
Publikováno v:
International Journal of Medical Sciences, Vol 9, Iss 8, Pp 690-697 (2012)
Trigeminal neuropathic pain is a facial pain syndrome associated with trigeminal nerve injury. However, the mechanism of trigeminal neuropathic pain is poorly understood. This study aimed to determine the role of transient receptor potential vanilloi
Publikováno v:
Journal of Pharmacology & Pharmacotherapeutics
Objective: To investigate pharmacologically whether CaSRs are involved in the Ca 2+ antagonist-induced [Ca 2+]i elevation in gingival fibroblasts. Materials and Methods: Gin-1 cells, normal human gingival fibroblasts, were used as the material. The [
Autor:
Kunio Mizutari, Tatsuo Matsunaga, Kazusaku Kamiya, Yoshiaki Fujinami, Hideki Mutai, Masato Fujii
Publikováno v:
Neurochemistry International. 56:487-494
We previously reported that treatment of the rat cochlea with a mitochondrial toxin, 3-nitropropionic acid (3-NP), causes temporary to permanent hearing loss depending on the amount of the drug. Furthermore, apoptosis of cochlear lateral wall fibrocy
Publikováno v:
Journal of Hard Tissue Biology. 19:43-50
In the present study, we investigated the effects of a Kampo medicine hangeshashinto (TJ-14) on the production of prostaglandin E2 (PGE2), interleukin (IL)-6 and IL-8 by human gingival fibroblasts (HGFs) treated with lipopolysaccharide (LPS) from Por
Autor:
Toshiaki Ara, Ken-ichi Honjo, Yoshiaki Fujinami, Pao-Li Wang, Toshimi Hattori, Yasuhiro Imamura
Publikováno v:
Biological and Pharmaceutical Bulletin. 33:611-616
In the present study, we investigated the effects of a Kampo medicine Orento (TJ-120) on the production of prostaglandin E(2) (PGE(2)), interleukin (IL)-6 and IL-8 by human gingival fibroblasts (HGFs) treated with lipopolysaccharide from Porphyromona
Autor:
Nakano K, Yasuhiro Imamura, Yoshiaki Fujinami, Toshiyuki Kawakami, Fukui T, Pao-Li Wang, Shigeru Yanagisawa, Toshiaki Ara, Yoshihisa Fujigaki, Toshimi Hattori
Publikováno v:
Oral Diseases. 15:466-471
Objective: Passive smoking is the involuntary inhalation of cigarette smoke (CS) and has an adverse impact on oral health. We examined the effect of CS exposure on saliva and salivary glands (SGs). Methods: Cigarette smoke-exposed rats were intermitt
Publikováno v:
Journal of Hard Tissue Biology. 17:121-124
The aim of this study was to examine whether human gingival fibroblasts (HGFs) sustain to produce prostaglandin E 2 (PGE 2 ) in the presence of lipopolysaccharide (LPS). HGFs were treated with or without 10 ng/ml of LPS from Porphyromonas gingivalis