Zobrazeno 1 - 10
of 243
pro vyhledávání: '"Yoshiaki Fujii-Kuriyama"'
Autor:
Miki Tanaka, Tomoaki Okuda, Kouichi Itoh, Nami Ishihara, Ami Oguro, Yoshiaki Fujii-Kuriyama, Yu Nabetani, Megumi Yamamoto, Christoph F. A. Vogel, Yasuhiro Ishihara
Publikováno v:
Particle and Fibre Toxicology, Vol 20, Iss 1, Pp 1-14 (2023)
Abstract Background A recent epidemiological study showed that air pollution is closely involved in the prognosis of ischemic stroke. We and others have reported that microglial activation in ischemic stroke plays an important role in neuronal damage
Externí odkaz:
https://doaj.org/article/0b534191fd854352af87eb926b3f7659
Autor:
Kyoko Oh-oka, Yuko Kojima, Koichiro Uchida, Kimiko Yoda, Kayoko Ishimaru, Shotaro Nakajima, Jun Hemmi, Hiroshi Kano, Yoshiaki Fujii-Kuriyama, Ryohei Katoh, Hiroyuki Ito, Atsuhito Nakao
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 4, Iss 1, Pp 135-151 (2017)
Background & Aims: Mesalamine is a first-line drug for treatment of inflammatory bowel diseases (IBD). However, its mechanisms are not fully understood. CD4+ Foxp3+ regulatory T cells (Tregs) play a potential role in suppressing IBD. This study deter
Externí odkaz:
https://doaj.org/article/fa32002dd88e4216a17dac4d9e5ca334
Autor:
Tadatsugu TANIGUCHI, Masaharu SAKAL, Yoshiaki FUJII-KURIYAMA, Masami MURAMATSU, Shigeyasu KOBAYASHI, Tetsuo SUDO
Publikováno v:
Proceedings of the Japan Academy, Series B Physical & biological sciences; 2024, Vol. 100 Issue 1, p9-14, 6p
Publikováno v:
Histochem Cell Biol
Histochemistry and Cell Biology
Histochemistry and Cell Biology
The aryl hydrocarbon receptor (AhR) acts as a receptor that responds to ligands, including dioxin. The AhR–ligand complex translocates from the cytoplasm into the nucleus to induce gene expression. Because dioxin exposure impairs cognitive and neur
Publikováno v:
Histochemistry and Cell Biology. 156:293-293
Autor:
Ken-ichi Nakashima, Toshiyuki Tanaka, Kouichi Kaburagi, Yoshiaki Fujii-Kuriyama, Hiroko Murata, Hidetoshi Hayashi, Takumi Ogiwara, Takao Hirai, Makoto Inoue
Publikováno v:
Bioorganic & Medicinal Chemistry. 25:4253-4258
The aryl hydrocarbon receptor (AhR) is a ligand-dependent transcriptional factor belonging to the basic helix-loop-helix-Per-Ahr/Arnt-Sim family. In this study, we evaluated the AhR agonistic activities of 12 xanthones isolated from the roots of M. c
Autor:
Hiroyuki Ito, Shotaro Nakajima, Jun Hemmi, Yoshiaki Fujii-Kuriyama, Yuko Kojima, Ryohei Katoh, Kyoko Oh-oka, Kimiko Yoda, Hiroshi Kano, Kayoko Ishimaru, Koichiro Uchida, Atsuhito Nakao
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 4, Iss 1, Pp 135-151 (2017)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Mesalamine is a first-line drug for treatment of inflammatory bowel diseases (IBD). However, its mechanisms are not fully understood. CD4+ Foxp3+ regulatory T cells (Tregs) play a potential role in suppressing IBD. This study determ
Autor:
Wen Su, Margaret Warner, Wanfu Wu, Yoshiaki Fujii-Kuriyama, Jan-Åke Gustafsson, Yubing Dai, Bo Huang, Ryan Butler, Yifei Miao
Publikováno v:
Proceedings of the National Academy of Sciences. 113:11883-11888
The aryl hydrocarbon receptor (AhR) is now recognized as an important physiological regulator in the immune and reproductive systems, and in the development of the liver and vascular system. AhR regulates cell cycle, cell proliferation, and different
Autor:
Takashi Tanaka, Tetsuji Naka, Hiroshi Handa, Takumi Ito, Masayuki Kitajima, Akihiko Yoshimura, Satoshi Serada, Minoru Fujimoto, Kyoko Nishida, Satoshi Sakamato, Harumi Suzuki, Yoshiaki Fujii-Kuriyama, Akihiro Kimura
Publikováno v:
The Journal of Experimental Medicine
Kimura et al. demonstrate that NQO1 plays a crucial role in degrading IκB-ζ protein through forming the complex together with PDLIM2 and selectively suppresses IL-6 and IL-12 production induced by TLR ligands.
NAD(P)H:quinone oxidoreductase 1
NAD(P)H:quinone oxidoreductase 1
Publikováno v:
Biochemical and Biophysical Research Communications. 450:416-422
Bone mass is regulated by various molecules including endogenous factors as well as exogenous factors, such as nutrients and pollutants. Aryl hydrocarbon receptor (AhR) is known as a dioxin receptor and is responsible for various pathological and phy