Výsledky vyhledávání - "Yoshiaki, Yano"

Effects of Gly Residue and Cholesterol on the GXXXG‐Mediated Parallel Association of Transmembrane Helices: A Single‐Pair FRET Study

Autor: Yoshiaki Yano, Takayuki Morise, Katsumi Matsuzaki

Publikováno v: ChemBioChem. 23

Small residue-mediated interhelical packing is ubiquitous in helical membrane proteins: however, the lipid dependence of its stability remains unclear. We previously demonstrated that the introduction of a GXXXG sequence in the middle of de novo -des

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c524b2bdcfbdfe12f195aeaac9c5c4b2
https://doi.org/10.1002/cbic.202200160

Zobrazit plný text záznamu

Difficulty in activities of daily living and falls in patients undergoing hemodialysis : A cross-sectional study with nondialysis controls

Autor: Yoshihiro Tsujimoto, Shoko Tsuchikura, Masanori Emoto, Mizuki Miyabe, Shota Matsufuji, Hiroshi Kishimoto, Asako Tamaru, Yoshiaki Yano, Tetsuo Shoji

Publikováno v: Hemodialysis International. 25(3):338-347

INTRODUCTION Impaired activities of daily living (ADL) and falls are important issues in hemodialysis patients. So far, information is limited regarding self-reported difficulty with ADL (ADL difficulty) in hemodialysis patients. Then, we compared th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b336e8c74544cd2265d7fbb1c276215c
https://dlisv03.media.osaka-cu.ac.jp/il/meta_pub/G0000438repository_15424758-25-3-338

Zobrazit plný text záznamu

Effects of Membrane Cholesterol on Stability of Transmembrane Helix Associations

Autor: Yoshiaki Yano

Publikováno v: Chemicalpharmaceutical bulletin. 70(8)

Membrane cholesterol is an essential and abundant component of eukaryotic cell membranes. The unique chemical structure of cholesterol significantly influences the physicochemical properties of phospholipid bilayers, such as hydrophobic thickness and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a2fd0fad04250dd3301eebaa9601a56
https://pubmed.ncbi.nlm.nih.gov/35908915

Zobrazit plný text záznamu

All-Atom Molecular Dynamics Elucidating Molecular Mechanisms of Single-Transmembrane Model Peptide Dimerization in a Lipid Bilayer

Autor: Kota Kasahara, Takuya Takahashi, Katsumi Matsuzaki, Hayato Itaya, Yoshiaki Yano, Qilin Xie

Publikováno v: ACS Omega, Vol 6, Iss 17, Pp 11458-11465 (2021)
ACS Omega

Protein-protein interactions between transmembrane helices are essential elements for membrane protein structures and functions. To understand the effects of peptide sequences and lipid compositions on these interactions, single-molecule experiments

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f5a241bcaf788559d38df9bf17cee17
https://doaj.org/article/ebac68df738547eea83db9d50870c4ab

Zobrazit plný text záznamu

Improvement of Therapeutic Index by the Combination of Enhanced Peptide Cationicity and Proline Introduction

Autor: Erika Azuma, Mayu Odaki, Katsumi Matsuzaki, Yoshiaki Yano, Naoki Choda

Publikováno v: ACS Infectious Diseases. 6:2271-2278

Antimicrobial peptides (AMPs) are promising candidates for new therapeutics to combat the emergence of an increasing number of multidrug-resistant pathogens. However, a major obstacle to the systemic application of AMPs is their possible toxicity. In

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0732eb5f9d14e2589e801f8f1151d82b
https://doi.org/10.1021/acsinfecdis.0c00387

Zobrazit plný text záznamu

In-Cell FRET Indicates Magainin Peptide Induced Permeabilization of Bacterial Cell Membranes at Lower Peptide-to-Lipid Ratios Relevant to Liposomal Studies

Autor: Takumi Kaji, Katsumi Matsuzaki, Yoshiaki Yano

Publikováno v: ACS infectious diseases. 7(10)

Antimicrobial peptides (AMPs) are promising candidates for anti-infective drugs. The majority of AMPs are considered to disrupt the lipid matrix of bacterial membranes, exerting bactericidal activity. A number of biophysical studies have been carried

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d174c5887be4cfc07221763074317ea
https://pubmed.ncbi.nlm.nih.gov/34514779

Zobrazit plný text záznamu

Live-cell imaging of membrane proteins by a coiled-coil labeling method—Principles and applications

Autor: Katsumi Matsuzaki, Yoshiaki Yano

Publikováno v: Biochimica et Biophysica Acta (BBA) - Biomembranes. 1861:1011-1017

In situ investigations in living cell membranes are important to elucidate the dynamic behaviors of membrane proteins in complex biomembrane environments. Protein-specific labeling is a key technique for the detection of a target protein by fluoresce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdb17793d0f5d59de9b9cc5547fbba94
https://doi.org/10.1016/j.bbamem.2019.02.009

Zobrazit plný text záznamu

[Cell-surface Initial Aggregation Process of Amyloid-β Peptides Studied by Fluorescence Correlation Spectroscopy]

Autor: Yoshiaki Yano

Publikováno v: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 141(6)

The formation of neurotoxic aggregates by amyloid-β peptide (Aβ) is considered to be a key step in the onset of Alzheimer's disease. It is widely accepted that oligomers are more neurotoxic than amyloid fibrils in the aqueous-phase aggregation of A

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::769a45535af24a45b80ff0b71b08601d
https://pubmed.ncbi.nlm.nih.gov/34078789

Zobrazit plný text záznamu

Thermodynamic and kinetic stabilities of transmembrane helix bundles as revealed by single-pair FRET analysis: Effects of the number of membrane-spanning segments and cholesterol

Autor: Yuta Watanabe, Yoshiaki Yano, Katsumi Matsuzaki

Publikováno v: Biochimica et Biophysica Acta (BBA) - Biomembranes. 1863(3)

The tertiary structures and conformational dynamics of transmembrane (TM) helical proteins are maintained by the interhelical interaction network in membranes, although it is complicated to analyze the underlying driving forces because the amino acid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57c085404fc33449dd5351fd9e762ff1
http://hdl.handle.net/2433/266569

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání