Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Yoshiaki, Ochi"'
Autor:
Hisashi Nishiwaki, Kosuke Nishi, Tuti Wukirsari, Taro Kishida, Takuya Sugahara, Satoshi Yamauchi, Koichi Akiyama, Yoshiaki Ochi
Publikováno v:
Bioorganicmedicinal chemistry letters. 27(17)
The new lignano-9,9'-lactones (α,β-dibenzyl-γ-butyrolactone lignans), which showed the higher cytotoxicity than arctigenin, were synthesized. The well-known cytotoxic arctigenin showed activity against HL-60 cells (EC50=12μM), however, it was ina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56f36b9a537d1b70b1e8ef0abdfbe943
https://pubmed.ncbi.nlm.nih.gov/28754364
https://pubmed.ncbi.nlm.nih.gov/28754364
Autor:
Yoshiharu Uruno, Atsushi Kitamura, Takeshi Enomoto, Akihiko Kiyoshi, Yoshiaki Ochi, Takaaki Sumiyoshi, Yasuko Konishi, Tomokazu Nakako, Atsushi Suwa, Harumi Matsuda, Kentaro Takai, Mutsuko Sakai, Yasuaki Uematsu
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 24:2909-2912
We designed and synthesized novel N-sulfonyl-7-azaindoline derivatives as selective M4 muscarinic acetylcholine receptor agonists. Modification of the N-carbethoxy piperidine moiety of compound 2, an M4 muscarinic acetylcholine receptor (mAChR)-prefe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4d8f2e8dcfab4fa60b40eac642c9174
https://doi.org/10.1016/j.bmcl.2014.04.083
https://doi.org/10.1016/j.bmcl.2014.04.083
Autor:
Makoto Oka, Tomoko Kinoshita, Kiyoshi Furukawa, Keiko Nakamichi, Hitoshi Kohayakawa, Atsuko Kita, Yoshiaki Ochi, Kurumiya Satoshi
Publikováno v:
British Journal of Pharmacology. 142:1059-1072
We investigated the ability of N-benzyl-N-ethyl-2-(7,8-dihydro-7-methyl-8-oxo-2-phenyl-9H-purin-9-yl)acetamide (AC-5216), a novel mitochondrial benzodiazepine receptor (MBR) ligand, to produce anti-anxiety and antidepressant-like effects in various a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb409ed8a9ebe77280e5a07979b84a84
https://doi.org/10.1038/sj.bjp.0705681
https://doi.org/10.1038/sj.bjp.0705681
Publikováno v:
Optics Express. 25:1769
application/pdf
Article
Optics Express. 2017, 25 (3), p.1769-1777
Article
Optics Express. 2017, 25 (3), p.1769-1777
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b97c94136641b99868913f2b8a921e8
https://doi.org/10.1364/oe.25.001769
https://doi.org/10.1364/oe.25.001769
Autor:
Yasuji Furutani, Yuki Hatayama, Hitoshi Kohayakawa, Tomoko Kiyoshi, Naoyuki Yoshida, Takashi Hashimoto, Yoshiaki Ochi
Publikováno v:
Alzheimer's & Dementia. 7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cb509ee8f2be83c83a87aa32da37c15
https://doi.org/10.1016/j.jalz.2011.05.1879
https://doi.org/10.1016/j.jalz.2011.05.1879
Autor:
Takeshi, Goromaru, Naofumi, Morita, Yuki, Hase, Yoshiaki, Ochi, Yoshitake, Shinohara, Kojiro, Takahashi, Seiji, Eto
Publikováno v:
Gan to kagaku ryoho. Cancerchemotherapy. 38(4)
The use of injectable generic antineoplastic agents has been increasing. Few studies have compared the quality and adverse reactions of generic and branded antineoplastic agents; and therefore, generic agents have not gained wide acceptance. Paclitax
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bba586e5203ad8ef4e52dd79f724276a
https://pubmed.ncbi.nlm.nih.gov/21498990
https://pubmed.ncbi.nlm.nih.gov/21498990
Autor:
Atsuko, Kita, Hitoshi, Kohayakawa, Tomoko, Kinoshita, Yoshiaki, Ochi, Keiko, Nakamichi, Satoshi, Kurumiya, Kiyoshi, Furukawa, Makoto, Oka
Publikováno v:
British journal of pharmacology. 142(7)
We investigated the ability of N-benzyl-N-ethyl-2-(7,8-dihydro-7-methyl-8-oxo-2-phenyl-9H-purin-9-yl)acetamide (AC-5216), a novel mitochondrial benzodiazepine receptor (MBR) ligand, to produce anti-anxiety and antidepressant-like effects in various a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fa572b3b4d0474c41c8754ab3c6fd6de
https://pubmed.ncbi.nlm.nih.gov/15249420
https://pubmed.ncbi.nlm.nih.gov/15249420
Autor:
Takashi Miyoshi, Mitsuru Funato, Yoon Seok Kim, Akio Kaneta, Yoshiaki Ochi, Shinichi Nagahama, Yoichi Kawakami
Publikováno v:
Applied Physics Express. 6:122704
The optical gain properties of InGaN-based green (512 nm) laser diodes fabricated on (0001) GaN substrates are investigated. Fitting simulations to the experimental gain spectra provides a Gaussian inhomogeneous broadening of 95 meV, an optical confi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75aa4d4f7125948422032f0330971466
https://doi.org/10.7567/apex.6.122704
https://doi.org/10.7567/apex.6.122704
Publikováno v:
Pharmacology, biochemistry, and behavior. 38(2)
The present study was undertaken to investigate the role of cholinergic mechanisms in the behavioral effects of RU-24969, a compound with serotonin1B (5-HT1B) receptor agonist properties. RU-24969 caused an increase in locomotion (2−5 mg/kg IP) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bccd21e24a30b3b3b0cf86107de8b3f
https://pubmed.ncbi.nlm.nih.gov/2057513
https://pubmed.ncbi.nlm.nih.gov/2057513
Publikováno v:
Japanese Journal of Pharmacology. 79:233
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7178d62a3100bfccea79c03bbc291d3d
https://doi.org/10.1016/s0021-5198(19)34946-7
https://doi.org/10.1016/s0021-5198(19)34946-7