Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Yoshiaki, Kikkawa"'
Autor:
Sakiko Toyama, Tomoko Honda, Sadahiro Iwabuchi, Shinichi Hashimoto, Kenzaburo Yamaji, Yuko Tokunaga, Yusuke Matsumoto, Hideya Kawaji, Takashi Miyazaki, Yoshiaki Kikkawa, Michinori Kohara
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Intranasal vaccines that elicit mucosal immunity are deemed effective against respiratory tract infections such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), but their ability to induce humoral immunity characterized by immunoglobu
Externí odkaz:
https://doaj.org/article/36f123777df6497f99fe3e9525a11e9a
Autor:
Shumpei P. Yasuda, Yuki Miyasaka, Xuehan Hou, Yo Obara, Hiroshi Shitara, Yuta Seki, Kunie Matsuoka, Ai Takahashi, Eri Wakai, Hiroshi Hibino, Toyoyuki Takada, Toshihiko Shiroishi, Ryo Kominami, Yoshiaki Kikkawa
Publikováno v:
Biomedicines, Vol 10, Iss 9, p 2221 (2022)
An MSM/Ms strain was established using Japanese wild mice, which exhibit resistance to several phenotypes associated with aging, such as obesity, inflammation, and tumorigenesis, compared to common inbred mouse strains. MSM/Ms strain is resistant to
Externí odkaz:
https://doaj.org/article/b75c825ab039479b8e28c8ba546586f6
Autor:
Hiroko Beppu, Tatsuya Fukuda, Naoya Otsubo, Tomoko Kawanishi, Toshie Ogawa, Yasutomo Abe, Mariko Endo, Tomohide Hanawa, Chise Sugita, Yoshiaki Kikkawa, Shuji Hatakeyama, Tetsuya Yamada, Sachiko Wakai
Publikováno v:
Nephrology. 28:240-248
Autor:
Takahiro Sanada, Yuichi Hirata, Yutaka Naito, Naoki Yamamoto, Yoshiaki Kikkawa, Yuji Ishida, Chihiro Yamasaki, Chise Tateno, Takahiro Ochiya, Michinori Kohara
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 3, Iss 2, Pp 272-283 (2017)
Background & Aims: An extracellular vesicle (EV) is a nanovesicle that shuttles proteins, nucleic acids, and lipids, thereby influencing cell behavior. A recent crop of reports have shown that EVs are involved in infectious biology, influencing host
Externí odkaz:
https://doaj.org/article/7e01847223e2459084043aaacbf8b048
Autor:
Masao Horie, Kazuyuki Mekada, Hiromi Sano, Yoshiaki Kikkawa, Satomi Chiken, Takuro Someya, Keisuke Saito, M Ibrahim Hossain, Masaaki Nameta, Kuniya Abe, Kenji Sakimura, Katsuhiko Ono, Atsushi Nambu, Atsushi Yoshiki, Hirohide Takebayashi
Publikováno v:
Neurobiology of Disease, Vol 96, Iss , Pp 271-283 (2016)
We identified a novel spontaneous mutant mouse showing motor symptoms that are similar to those of the dystonia musculorum (dt) mouse. The observations suggested that the mutant mice inherited the mild dt phenotype as an autosomal recessive trait. Li
Externí odkaz:
https://doaj.org/article/7de5d94cde7e44a5b8f6aa19a07c5e06
Autor:
Ikuo, Miura, Yoshiaki, Kikkawa, Shumpei P, Yasuda, Akiko, Shinogi, Daiki, Usuda, Vivek, Kumar, Joseph S, Takahashi, Masaru, Tamura, Hiroshi, Masuya, Shigeharu, Wakana
Publikováno v:
Experimental Animals. 71:240-251
Forward genetics is a powerful approach based on chromosomal mapping of phenotypes and has successfully led to the discovery of many mouse mutations in genes responsible for various phenotypes. Although crossing between genetically remote strains can
Autor:
Yuta Seki, Yuki Miyasaka, Sari Suzuki, Kenta Wada, Shumpei P Yasuda, Kunie Matsuoka, Yasuhiro Ohshiba, Kentaro Endo, Rie Ishii, Hiroshi Shitara, Shin-Ichiro Kitajiri, Naomi Nakagata, Hirohide Takebayashi, Yoshiaki Kikkawa
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0183477 (2017)
An unconventional myosin encoded by the myosin VI gene (MYO6) contributes to hearing loss in humans. Homozygous mutations of MYO6 result in nonsyndromic profound congenital hearing loss, DFNB37. Kumamoto shaker/waltzer (ksv) mice harbor spontaneous m
Externí odkaz:
https://doaj.org/article/c1e4ee1bdd074964b8ea025c2bba01e6
Autor:
Yoshiaki Kikkawa, Chie Shimamoto-Mitsuyama, Motoko Maekawa, Shabeesh Balan, Tetsuro Ohmori, Hisako Ohba, Akiko Watanabe, Tomomi Shimogori, Tetsuo Ohnishi, Takeo Yoshikawa, Shusuke Numata, Yoshimi Iwayama, Tomoko Toyota, Manabu Toyoshima, Yasuko Hisano, Takeshi Hayashi, Yuki Miyasaka, Tomonori Hara
Publikováno v:
Schizophrenia Bulletin
We previously identified quantitative trait loci (QTL) for prepulse inhibition (PPI), an endophenotype of schizophrenia, on mouse chromosome 10 and reported Fabp7 as a candidate gene from an analysis of F2 mice from inbred strains with high (C57BL/6N
Autor:
Hiroshi Shitara, Yuki Miyasaka, Yasumasa Nishito, Shumpei P. Yasuda, Kunie Matsuoka, Kenta Wada, Choji Taya, Yuta Seki, Yoshiaki Kikkawa, Hiromichi Yonekawa
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-17 (2019)
Scientific Reports
Scientific Reports
Outer hair cells (OHCs) are responsible for the amplification of sound, and the death of these cells leads to hearing loss. Although the mechanisms for sound amplification and OHC death have been well investigated, the effects on the cochlea after OH
Autor:
Kenta Wada, Yoshibumi Matsushima, Tomoki Tada, Sayaka Hasegawa, Yo Obara, Yasuhiro Yoshizawa, Gou Takahashi, Hiroshi Hiai, Midori Shimanuki, Sari Suzuki, Junichi Saitou, Naoki Yamamoto, Masumi Ichikawa, Kei Watanabe, Yoshiaki Kikkawa
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e111432 (2014)
Microphthalmia is a severe ocular disorder, and this condition is typically caused by mutations in transcription factors that are involved in eye development. Mice carrying mutations in these transcription factors would be useful tools for defining t
Externí odkaz:
https://doaj.org/article/06646f858edb4fc3a91f62cd2ce2d139