Zobrazeno 1 - 10 of 99 pro vyhledávání: '"Yoshiaki, Furuya"'
1
Akademický článek
Discovery of E2730, a novel selective uncompetitive GAT1 inhibitor, as a candidate for anti‐seizure medication
Autor: Kazuyuki Fukushima, Hiroyuki Higashiyama, Yuji Kazuta, Keisuke Hashimoto, Naoto Watanabe, Yoshiaki Furuya, Yoshimasa Ito, Ting Wu, Takashi Kosasa, Delia M. Talos, Yeri Song, Nicholas S. Roberts, Frances E. Jensen, Takahisa Hanada, Katsutoshi Ido
Publikováno v: Epilepsia Open, Vol 8, Iss 3, Pp 834-845 (2023)
Abstract Objective As of 2022, 36 anti‐seizure medications (ASMs) have been licensed for the treatment of epilepsy, however, adverse effects (AEs) are commonly reported. Therefore, ASMs with a wide margin between therapeutic effects and AEs are pre
Externí odkaz: https://doaj.org/article/f701ca4aa9704aca88c101bf7dd510b7
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2
Akademický článek
Administration of combined venetoclax and azacitidine in a patient with acute myeloid leukemia and multiple comorbidities undergoing dialysis: A case report
Autor: Yuina Akagi, Yusuke Yamashita, Hideki Kosako, Yoshiaki Furuya, Hiroki Hosoi, Toshiki Mushino, Shogo Murata, Akinori Nishikawa, Shinobu Tamura, Taisei Nakao, Takashi Sonoki
Publikováno v: eJHaem, Vol 4, Iss 3, Pp 841-843 (2023)
Abstract Patients with acute myeloid leukemia (AML) who have comorbidities have limited treatment options, thereby resulting in poor prognosis. Venetoclax, a specific B‐cell lymphoma‐2 inhibitor, has recently been approved for AML in combination
Externí odkaz: https://doaj.org/article/629d557389714eaca20bef5df4661a5f
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3
Akademický článek
Use of thromboelastography before the administration of hemostatic agents to safely taper recombinant activated factor VII in acquired hemophilia A: a report of three cases
Autor: Hiroki Hosoi, Yuina Akagi, Toshiki Mushino, Masahiro Takeyama, Naoto Minoura, Takayuki Hiroi, Yoshiaki Furuya, Masaya Morimoto, Shogo Murata, Shinobu Tamura, Takashi Sonoki
Publikováno v: Thrombosis Journal, Vol 20, Iss 1, Pp 1-7 (2022)
Abstract Background Acquired hemophilia A (AHA) is a rare autoimmune disease characterized by bleeding events. Recombinant activated factor VII (rFVIIa) is a first-line bypassing agent, which is effective against clinically significant bleeding. Howe
Externí odkaz: https://doaj.org/article/16687304e7854ae2af5cca2cf091f2ef
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4
Akademický článek
Efficacy of genogroup 1 based porcine epidemic diarrhea live vaccine against genogroup 2 field strain in Japan
Autor: Tetsuo Sato, Kazuki Oroku, Yoshiyuki Ohshima, Yoshiaki Furuya, Chihiro Sasakawa
Publikováno v: Virology Journal, Vol 15, Iss 1, Pp 1-8 (2018)
Abstract Background Porcine epidemic diarrhea (PED) is a lethal infectious disease in suckling piglets with symptoms including watery diarrhea caused by PED virus (PEDV). Since the late 1990’s, live vaccines based on genogroup 1 virus have been use
Externí odkaz: https://doaj.org/article/539cdc16e6da4f21ba5b65e276ebbadc
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7
A Patient with Kabuki Syndrome Mutation Presenting with Very Severe Aplastic Anemia
Autor: Akira Kinoshita, Yusuke Yamashita, Hiroyuki Mishima, Shinobu Tamura, Toshiki Mushino, Akinori Nishikawa, Yoshiaki Furuya, Takashi Sonoki, Ko-ichiro Yoshiura, Hideki Kosako
Publikováno v: Acta Haematologica. 145:89-96
Kabuki syndrome (KS) is a rare congenital disorder commonly complicated by humoral immunodeficiency. Patients with KS present with mutation in the histone-lysine N-methyltransferase 2D (KMT2D) gene. Although various KMT2D mutations are often identifi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4475f53f9b8a2ca8670a382be03ec381
https://doi.org/10.1159/000518227
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9
[Paroxysmal nocturnal hemoglobinuria treated with eculizumab in Wakayama, Japan: a retrospective analysis]
Autor: Shinobu, Tamura, Yoshiaki, Furuya, Yoshikazu, Hori, Takayuki, Hiroi, Yusuke, Yamashita, Takehiro, Oiwa, Shogo, Murata, Toshiki, Mushino, Akinori, Nishikawa, Nobuyoshi, Hanaoka, Takashi, Sonoki
Publikováno v: [Rinsho ketsueki] The Japanese journal of clinical hematology. 61(6)
Currently, the humanized anti-C5 monoclonal antibody, eculizumab, is widely used for treating paroxysmal nocturnal hemoglobinuria (PNH) due to its effects on suppression of intravascular hemolysis and resulting improvement in quality of life. However
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b8ba70db51a5d2d49c2792d40e3ad7c4
https://pubmed.ncbi.nlm.nih.gov/32624532
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10
Akademický článek
Interleukin-6 as a Potential Therapeutic Target for Pulmonary Arterial Hypertension
Autor: Yoshiaki Furuya, Toru Satoh, Masataka Kuwana
Publikováno v: International Journal of Rheumatology, Vol 2010 (2010)
Interleukin-6 (IL-6) is a pleiotropic cytokine with a wide range of biologic activities in immune regulation, hematopoiesis, inflammation, and oncogenesis. Recent accumulating evidence indicates a pathologic role for IL-6 in promoting proliferation o
Externí odkaz: https://doaj.org/article/2f0a5c55d1a042fd8eb608f33a9986a7
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