Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Yosef Sabo"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract The human respiratory syncytial virus (hRSV) and the human metapneumovirus (hMPV) are important human respiratory pathogens from the Pneumoviridae family. Both are responsible for severe respiratory tract infections in infants, young childre
Externí odkaz:
https://doaj.org/article/00903c5abebc4a8daf93dab7568a1e74
Publikováno v:
Cell Reports, Vol 30, Iss 12, Pp 4065-4081.e4 (2020)
Summary: IQGAP1 is a master regulator of many cellular processes, including intracellular vesicle trafficking and endocytosis. We show that depletion of IQGAP1 in a variety of cell types increases the release of HIV-1 infectious virions and that over
Externí odkaz:
https://doaj.org/article/efc7777fa6ff46f1a0a292a444fb3fc8
Publikováno v:
mBio, Vol 10, Iss 6 (2019)
ABSTRACT Conjugation of small ubiquitin-like modifiers (SUMOs) to substrate proteins is a posttranslational protein modification that affects a diverse range of physiological processes. Global inhibition of SUMO conjugation in mice results in embryon
Externí odkaz:
https://doaj.org/article/cce4db26578d48369ff50646e0205640
Autor:
Qingqing Chai, Vladimir Jovasevic, Viacheslav Malikov, Yosef Sabo, Scott Morham, Derek Walsh, Mojgan H. Naghavi
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
HIV infection results in elevated beta-amyloid (Aβ) levels in the brain, but the underlying mechanisms are unclear. Here, the authors show that amyloid precursor protein inhibits virion production and that HIV Gag, counteracting this antiviral funct
Externí odkaz:
https://doaj.org/article/4bb6852761304008b18756776bcceede
Autor:
Qingqing Chai, Vladimir Jovasevic, Viacheslav Malikov, Yosef Sabo, Scott Morham, Derek Walsh, Mojgan H. Naghavi
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
The original version of this Article contained an error in the Methods section ‘Viruses and drugs’. The timing for drug treatment of CHME3 4 × 4 or 293T cells with γ-secretase inhibitor or BACE1 inhibitor was incorrectly given as ‘1 day prior
Externí odkaz:
https://doaj.org/article/6c026654b4044287a63e0ddea5d16de2
Autor:
Sho Iketani, Hiroshi Mohri, Bruce Culbertson, Seo Jung Hong, Yinkai Duan, Maria I. Luck, Medini K. Annavajhala, Yicheng Guo, Zizhang Sheng, Anne-Catrin Uhlemann, Stephen P. Goff, Yosef Sabo, Haitao Yang, Alejandro Chavez, David D. Ho
Publikováno v:
bioRxiv
Nirmatrelvir, an oral antiviral targeting the 3CL protease of SARS-CoV-2, has been demonstrated to be clinically useful in reducing hospitalization or death due to COVID-191,2. However, as SARS-CoV-2 has evolved to become resistant to other therapeut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::366633746ed68c77c4581ff710563a55
https://pubmed.ncbi.nlm.nih.gov/36032976
https://pubmed.ncbi.nlm.nih.gov/36032976
Autor:
Sho Iketani, Seo Jung Hong, Jenny Sheng, Farideh Bahari, Bruce Culbertson, Fereshteh Fallah Atanaki, Arjun K. Aditham, Alexander F. Kratz, Maria I. Luck, Ruxiao Tian, Stephen P. Goff, Hesam Montazeri, Yosef Sabo, David D. Ho, Alejandro Chavez
Publikováno v:
bioRxiv
SummarySARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) as the etiologic agent of COVID-19 (coronavirus disease 2019) has drastically altered life globally. Numerous efforts have been placed on the development of therapeutics to treat SAR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0725fb8e2933ba84c97a75042592b7c7
https://doi.org/10.1101/2022.06.23.497404
https://doi.org/10.1101/2022.06.23.497404
Publikováno v:
Cell Reports, Vol 30, Iss 12, Pp 4065-4081.e4 (2020)
Cell reports
Cell reports
SUMMARY IQGAP1 is a master regulator of many cellular processes, including intracellular vesicle trafficking and endocytosis. We show that depletion of IQGAP1 in a variety of cell types increases the release of HIV-1 infectious virions and that overe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45168186b28f311aa4459194320fe799
http://www.sciencedirect.com/science/article/pii/S2211124720303004
http://www.sciencedirect.com/science/article/pii/S2211124720303004
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Invading viral DNAs constitute a high risk for the infected cell and are high-profile targets of antiviral host factors. Nevertheless, little is known about the silencing machinery in the nucleus that acts to prevent transcription or ret
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aba6da69a1a408851b05a04898371b02
https://pubmed.ncbi.nlm.nih.gov/35074917
https://pubmed.ncbi.nlm.nih.gov/35074917
Autor:
Sho Iketani, Seo Jung Hong, Jenny Sheng, Farideh Bahari, Bruce Culbertson, Fereshteh Fallah Atanaki, Arjun K. Aditham, Alexander F. Kratz, Maria I. Luck, Ruxiao Tian, Stephen P. Goff, Hesam Montazeri, Yosef Sabo, David D. Ho, Alejandro Chavez
Publikováno v:
Cell Host & Microbe. 30:1354-1362.e6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d06be3a52efe36f79825a579d9c6c24
https://doi.org/10.1016/j.chom.2022.08.003
https://doi.org/10.1016/j.chom.2022.08.003