Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Yosef Rosenfeld"'
Autor:
Noam Emanuel, Shlomo Nedvetzki, Yosef Rosenfeld, Goldi A. Kozloski, Malka Reichart, Anthony J. Senagore
Publikováno v:
Journal of Clinical Oncology. 40:e22530-e22530
e22530 Background: Local recurrence (LR) negatively impacts long-term survival and patients’ quality of life in many solid tumor malignancies, despite advances in surgical techniques and neoadjuvant and adjuvant treatments. Systemic treatment-relat
Publikováno v:
Biochemistry. 47:6468-6478
Endotoxin [lipopolysaccharide (LPS)] covers more than 90% of the outer monolayer of the outer membrane of Gram-negative bacteria, and it plays a dual role in its pathogenesis: as a protective barrier against antibiotics and as an effector molecule, w
Publikováno v:
Biochemistry. 46:12586-12593
Conus venoms are estimated to comprise over 100,000 distinct pharmacologically active peptides, the majority probably targeting ion channels. Through the characterization of a cytolytic peptide from the venom of Conus mustelinus, conolysin-Mt, we exp
Autor:
Xavier Lauth, Richard L. Gallo, Anjuli M. Timmer, Victor Nizet, Yechiel Shai, Sascha A. Kristian, George Y. Liu, Yosef Rosenfeld, Neta Sal-Man
Publikováno v:
The FASEB Journal. 21:1107-1116
Antibiotics are designed to support host defense in controlling infection. Here we describe a paradoxical inhibitory effect of bacteriostatic antibiotics on key mediators of mammalian innate immunity. When growth of species including Escherichia coli
Autor:
Yosef Rosenfeld, Yechiel Shai
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1758(9):1513-1522
Lipopolysaccharide (LPS) is the major molecular component of the outer membrane of Gram-negative bacteria and serves as a physical barrier providing the bacteria protection from its surroundings. LPS is also recognized by the immune system as a marke
Publikováno v:
Journal of Biological Chemistry. 281:1636-1643
Binding of lipopolysaccharide (LPS) to macrophages results in proinflammatory cytokine secretion. In extreme cases it leads to endotoxic shock. A few innate immunity antimicrobial peptides (AMPs) neutralize LPS activity. However, the underlying mecha
Effect of PhoP-PhoQ Activation by Broad Repertoire of Antimicrobial Peptides on Bacterial Resistance
Publikováno v:
Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2012, 287 (7), pp.4544-4551. ⟨10.1074/jbc.M111.278523⟩
Journal of Biological Chemistry, 2012, 287 (7), pp.4544-4551. ⟨10.1074/jbc.M111.278523⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2012, 287 (7), pp.4544-4551. ⟨10.1074/jbc.M111.278523⟩
Journal of Biological Chemistry, 2012, 287 (7), pp.4544-4551. ⟨10.1074/jbc.M111.278523⟩
International audience; Pathogenic bacteria can resist their microenvironment by changing the expression of virulence genes. In Salmonella typhimurium, some of these genes are controlled by the two-component system PhoP-PhoQ. Studies have shown that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9eb6a7df2be98bd9bb0fd0f4ac1aab46
https://hal-pasteur.archives-ouvertes.fr/pasteur-01300167
https://hal-pasteur.archives-ouvertes.fr/pasteur-01300167
Publikováno v:
Biochemistry. 49(5)
The interaction between host-defense antimicrobial peptides (AMPs) and the bacterial lipopolysaccharide (LPS) governs both the susceptibility of the bacteria to the peptide and the ability of the peptide to inhibit LPS activation of immune cells. Bot
Publikováno v:
Biophysical Journal. 96(3)
The molecular mechanism, by which bacteria sense antimicrobial peptides (AMPs) that promote its virulence is partially known. Bacteria are capable of changing the expression of virulence genes essential to survival and replication, by sensing changes
Autor:
Raquel F. Epand, Donatella Barra, Yosef Rosenfeld, Richard M. Epand, Maria Luisa Mangoni, Adi Peleg, Yechiel Shai
Publikováno v:
The Journal of biological chemistry. 283(34)
Lipopolysaccharide (LPS) is the major structural component of the outer membrane of Gram-negative bacteria and shields them from a variety of host defense factors, including antimicrobial peptides (AMPs). LPS is also recognized by immune cells as a p