Zobrazeno 1 - 10
of 16 110
pro vyhledávání: '"York P"'
Autor:
Philip Kam-Tao Li, Jack Kit-Chung Ng, Guang-yan Cai, Wei Chen, Kai Ming Chow, Stanley Fan, John Cijiang He, Lai Seong Hooi, York Pei, Boon Wee Teo, Muh Geot Wong, I-Wen Wu, Jianhui Zhou, Na Tian, Zhiming Ye, Xueqing Yu
Publikováno v:
Kidney Diseases, Pp 1-14 (2024)
Background: Chronic kidney disease (CKD) continues to be a significant global public health issue. The escalating burden of CKD is probably driven by the aging population and the rising prevalence of diabetes. CKD not only adversely impacts an indivi
Externí odkaz:
https://doaj.org/article/0ea1939371be403fa1ed2d51a1614bde
Autor:
Luca Calvaruso, Kevin Yau, Pedram Akbari, Fatemah Nasri, Saima Khowaja, Bill Wang, Amirreza Haghighi, Korosh Khalili, York Pei
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Tolvaptan is the first disease-modifying drug proven to slow eGFR decline in high-risk patients with ADPKD. However, barriers from the patient perspective to its use in real-life settings have not been systemically examined in a large cohort
Externí odkaz:
https://doaj.org/article/54d5760c63ec449a81ab9e00f4b2a7de
Myocardin-Related Transcription Factor Mediates Epithelial Fibrogenesis in Polycystic Kidney Disease
Autor:
Zsuzsanna Lichner, Mei Ding, Tarang Khare, Qinghong Dan, Raquel Benitez, Mercédesz Praszner, Xuewen Song, Rola Saleeb, Boris Hinz, York Pei, Katalin Szászi, András Kapus
Publikováno v:
Cells, Vol 13, Iss 11, p 984 (2024)
Polycystic kidney disease (PKD) is characterized by extensive cyst formation and progressive fibrosis. However, the molecular mechanisms whereby the loss/loss-of-function of Polycystin 1 or 2 (PC1/2) provokes fibrosis are largely unknown. The small G
Externí odkaz:
https://doaj.org/article/038cfb26b9a747ddb4a453e74f82412d
Autor:
Ioan-Andrei Iliuta, Aung Zaw Win, Matthew B. Lanktree, Seung Heyck Lee, Marina Pourafkari, Fatemeh Nasri, Elsa Guiard, Amirreza Haghighi, Ning He, Alistair Ingram, Crystal Quist, David Hillier, Korosh Khalili, York Pei
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-7 (2023)
Abstract Using age- and height-adjusted total kidney volume, the Mayo Clinic Imaging Classification provides a validated approach to assess the risk of chronic kidney disease (CKD) progression in autosomal dominant polycystic kidney disease (ADPKD),
Externí odkaz:
https://doaj.org/article/e2d58782aaf543f7aeb50d56b5a2e025
Autor:
Xuewen Song, Wouter N. Leonhard, Anish A. Kanhai, Gregory R. Steinberg, York Pei, Dorien J. M. Peters
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Background: Autosomal dominant polycystic kidney disease (ADPKD) is the most common genetic disorder and an important cause of end stage renal disease (ESRD). Tolvaptan (a V2R antagonist) is the first disease modifier drug for treatment of ADPKD, but
Externí odkaz:
https://doaj.org/article/48d465f4278047878c9c9eb75b978439
Autor:
Poornima Vijayan, Saidah Hack, Tony Yao, Mohammad Azfar Qureshi, Andrew D. Paterson, Rohan John, Bernard Davenport, Rachel Lennon, York Pei, Moumita Barua
Publikováno v:
BMC Nephrology, Vol 22, Iss 1, Pp 1-6 (2021)
Abstract Background Focal and segmental glomerulosclerosis (FSGS) is a histologic pattern of injury that characterizes a wide spectrum of diseases. Many genetic causes have been identified in FSGS but even in families with comprehensive testing, a si
Externí odkaz:
https://doaj.org/article/1baf9a696e0c489a99934778bbd0a795
Autor:
STIPS Development Team, Gomez, Sebastian, Bellini, Andrea, Al-Kowsi, Hanna, Desjardins, Tyler, Geda, Robel, Han, Eunkyu, Otor, O. Justin, Riedel, Adric, Ryan, Russell, Spitzer, Isaac, York, Brian
The Space Telescope Imaging Product Simulator (STIPS) is a Python-based package that can be used to simulate scenes from the upcoming \textit{Nancy Grace Roman Space Telescope} (\nancy). STIPS is able to generate post-pipeline astronomical images of
Externí odkaz:
http://arxiv.org/abs/2411.11978
Autor:
Skeens, Joe, York, Johnathan, Petrov, Leonid, Herrity, Kyle, Ji-Cathriner, Richard, Bettadpur, Srinivas
We have been developing a novel interferometer formed directly between a Very Long Baseline Interferometry (VLBI) radio telescope and a Global Navigation Satellite Systems (GNSS) antenna/receiver. This interferometer is enabled by the High Rate Track
Externí odkaz:
http://arxiv.org/abs/2410.14834
Autor:
Krause, Thorsten, Deriyeva, Alina, Beinke, Jan Heinrich, Bartels, Gerrit York, Thomas, Oliver
Through exposing items to users, implicit feedback recommender systems influence the logged interactions, and, ultimately, their own recommendations. This effect is called exposure bias and it can lead to issues such as filter bubbles and echo chambe
Externí odkaz:
http://arxiv.org/abs/2409.12912
Autor:
Ronald D. Perrone, Ali Hariri, Pascal Minini, Curie Ahn, Arlene B. Chapman, Shigeo Horie, Bertrand Knebelmann, Michal Mrug, Albert C.M. Ong, York P.C. Pei, Vicente E. Torres, Vijay Modur, Ronald T. Gansevoort
Publikováno v:
Kidney Medicine, Vol 4, Iss 10, Pp 100538- (2022)
Rationale & Objective: Venglustat, a glucosylceramide synthase inhibitor, inhibits cyst growth and reduces kidney failure in mouse models of autosomal dominant polycystic kidney disease (ADPKD). STAGED-PKD aims to determine the safety and efficacy of
Externí odkaz:
https://doaj.org/article/66ff3b0e6417477da59ccf6a9cdbba1d