Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Yoriomi Hamada"'
Autor:
Yoriomi Hamada, Takeshi Yamamoto, Yoshihide Nakamura, Yoko Sufu-Shimizu, Takuma Nanno, Masakazu Fukuda, Makoto Ono, Tesuro Oda, Shinichi Okuda, Takeshi Ueyama, Shigeki Kobayashi, Masafumi Yano
Publikováno v:
Biochemistry and Biophysics Reports, Vol 21, Iss , Pp - (2020)
Background: Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited heart disease that causes heart failure and/or sudden cardiac death. Several desmosomal genes (DSC2, PKG, PKP2, DSP, and RyR2) are thought to be the causative gene inv
Externí odkaz:
https://doaj.org/article/ae65b70166a1457e884fd63ac98543fb
Autor:
Masakazu Obayashi, Shigeki Kobayashi, Hirotaka Yamamoto, Yoriomi Hamada, Takumi Nanno, Michihiro Kohno, Masafumi Yano
Publikováno v:
Artery Research, Vol 25, Iss 1 (2020)
Background: Recently, we showed an age-related increase in augmentation pressure (AP) measured using Mobil-O-Graph (MOG) in normotensive Japanese individuals. However, AP might be a poor index of wave reflection due to the overlap between the forward
Externí odkaz:
https://doaj.org/article/9199ee72f352449791ea4d90a9247098
Publikováno v:
Pulse (Basel)
Introduction: The augmentation index (AIx) or central systolic blood pressure (SBP), measured by radial applanation tonometry, has been reported to be independently associated with left ventricular hypertrophy (LVH) in Japanese hypertensive patients.
Autor:
Takuma Nanno, Shigeki Kobayashi, Masafumi Yano, Takeshi Ueyama, Yoko Sufu-Shimizu, Yoshihide Nakamura, Takeshi Yamamoto, Shinichi Okuda, Yoriomi Hamada, Tesuro Oda, Masakazu Fukuda, Makoto Ono
Publikováno v:
Biochemistry and Biophysics Reports, Vol 21, Iss, Pp-(2020)
Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports
Background Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited heart disease that causes heart failure and/or sudden cardiac death. Several desmosomal genes (DSC2, PKG, PKP2, DSP, and RyR2) are thought to be the causative gene invo
Autor:
Yoko Sufu, Takuma Nanno, Xiaojuan Xu, Go Fukui, Hironori Ishiguchi, Masafumi Yano, Shigehiko Nishimura, Shinichi Okuda, Shigeki Kobayashi, Takeshi Yamamoto, Makoto Ono, Yoriomi Hamada, Yoshihide Nakamura, Tetsuro Oda, Michiaki Kohno, Takayoshi Kato
Publikováno v:
Heart Rhythm. 15:905-914
Background Ryanodine receptor (RyR2) is known to be a causal gene of catecholaminergic polymorphic ventricular tachycardia (CPVT), an important inherited disease. Some of the human CPVT-associated mutations have been found in a domain (4026-4172) tha
Autor:
Masafumi Yano, Hitoshi Uchinoumi, Tetsuro Oda, Xiaojuan Xu, Go Fukui, Shinichi Okuda, Shigehiko Nishimura, Shigeki Kobayashi, Yoriomi Hamada, Takeshi Yamamoto, Masaki Tamitani, Yoshihide Nakamura, Takayoshi Kato
Publikováno v:
Circulation Research. 125
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is caused by a single point mutation in the cardiac type 2 ryanodine receptor (RyR2). Using knock-in mouse (KI) model (R2474S/+), we previously reported that a single point mutation within
Autor:
Xiaojuan Xu, Tetsuro Oda, Yoshihide Nakamura, Hitoshi Uchinoumi, Shinichi Okuda, Takayoshi Kato, Yoriomi Hamada, Go Fukui, Shigeki Kobayashi, Masafumi Yano, Shigehiko Nishimura, Takeshi Yamamoto, Masaki Tamitani
Publikováno v:
JCI insight. 4(11)
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is caused by a single point mutation in the cardiac type 2 ryanodine receptor (RyR2). Using a knockin (KI) mouse model (R2474S/+), we previously reported that a single point mutation within
Autor:
Takayoshi Kato, Go Fukui, Yoriomi Hamada, Donald M. Bers, Shinichi Okuda, Yoshihide Nakamura, Yoko Okamoto, Hitoshi Uchinoumi, Masafumi Yano, Takeshi Yamamoto, Tetsuro Oda, Michiaki Kono, Takuma Nanno, Shigeki Kobayashi, Hironori Ishiguchi
Publikováno v:
Journal of molecular and cellular cardiology. 125
In cardiac myocytes Calmodulin (CaM) bound to the ryanodine receptor (RyR2) constitutes a large pool of total myocyte CaM, but the CaM-RyR2 affinity is reduced in pathological conditions. Knock-in mice expressing RyR2 unable to bind CaM also develope
Autor:
Tomoyuki Murakami, Hideo Yanai, Hideto Hayashi, Tatsunori Cyubachi, Yoriomi Hamada, Eiki Sakaguchi, Takumi Furuya
Publikováno v:
Yamaguchi Medical Journal. 63:167-172
Autor:
Xiaojuan Xu, Shinichi Okuda, Masakazu Fukuda, Yoshihide Nakamura, Hiroyuki Kyushiki, Hironori Ishiguchi, Akihiro Hino, Wakako Murakami, Takako Maeda, Makoto Ono, Tetsuro Oda, Takeshi Yamamoto, Yoriomi Hamada, Noritaka Koseki, Shigeki Kobayashi, Masafumi Yano, Takuma Nanno, Takayoshi Kato, Go Fukui, Shigehiko Nishimura, Yoko Sufu
Publikováno v:
Heart rhythm. 14(1)
Background Calmodulin (CaM) is a key modulator of the channel gating function of the ryanodine receptor (RyR). Objective The purpose of this study was to investigate the pathogenic role of RyR-bound CaM in diastolic Ca 2+ leakage from the sarcoplasmi