Zn(OTf)2-mediated annulations of N-propargylated tetrahydrocarbolines: divergent synthesis of four distinct alkaloidal scaffolds† †Electronic supplementary information (ESI) available. CCDC 1905889, 1905890 and 1905916. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c9sc01507h

Autor: Yorimoto, Sadaiwa, Tsubouchi, Akira, Mizoguchi, Haruki, Oikawa, Hideaki, Tsunekawa, Yoshiaki, Ichino, Tomoya, Maeda, Satoshi, Oguri, Hiroki

Publikováno v: Chemical Science

Experimental and computational studies gained insights into Zn(OTf)2-mediated annulations and allowed programmable synthesis of four distinct alkaloidal scaffolds.
Intramolecular hydroarylations of N-propargylated tetrahydrocarbolines were effic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::24ad632943450956d25675be6e0ea8f3
http://europepmc.org/articles/PMC6568280

Zn(OTf) 2 -mediated annulations of N -propargylated tetrahydrocarbolines: divergent synthesis of four distinct alkaloidal scaffolds.

Autor: Yorimoto S; Department of Applied Chemistry , Graduate School of Engineering , Tokyo University of Agriculture and Technology , 2-24-16 Nakacho , Koganei , Tokyo 184-8588 , Japan . Email: h_oguri@cc.tuat.ac.jp., Tsubouchi A; Department of Applied Chemistry , Graduate School of Engineering , Tokyo University of Agriculture and Technology , 2-24-16 Nakacho , Koganei , Tokyo 184-8588 , Japan . Email: h_oguri@cc.tuat.ac.jp., Mizoguchi H; Graduate School of Natural Science and Technology , Okayama University , 3-1-1 Tsushimanaka, Kita-ku , Okayama 700-8530 , Japan., Oikawa H; Department of Chemistry , Faculty of Science , Hokkaido University , Kita-ku Kita 10 Jo Nishi 8 Chome , Sapporo 060-0810 , Japan . Email: smaeda@eis.hokudai.ac.jp., Tsunekawa Y; Department of Chemistry , Faculty of Science , Hokkaido University , Kita-ku Kita 10 Jo Nishi 8 Chome , Sapporo 060-0810 , Japan . Email: smaeda@eis.hokudai.ac.jp., Ichino T; Department of Chemistry , Faculty of Science , Hokkaido University , Kita-ku Kita 10 Jo Nishi 8 Chome , Sapporo 060-0810 , Japan . Email: smaeda@eis.hokudai.ac.jp., Maeda S; Department of Chemistry , Faculty of Science , Hokkaido University , Kita-ku Kita 10 Jo Nishi 8 Chome , Sapporo 060-0810 , Japan . Email: smaeda@eis.hokudai.ac.jp.; Institute for Chemical Reaction Design and Discovery (WPI-ICReDD) , Hokkaido University , Sapporo 001-0021 , Japan., Oguri H; Department of Applied Chemistry , Graduate School of Engineering , Tokyo University of Agriculture and Technology , 2-24-16 Nakacho , Koganei , Tokyo 184-8588 , Japan . Email: h_oguri@cc.tuat.ac.jp.

Publikováno v: Chemical science [Chem Sci] 2019 May 01; Vol. 10 (22), pp. 5686-5698. Date of Electronic Publication: 2019 May 01 (Print Publication: 2019).