Výsledky vyhledávání - "Yoriko Tajima"

Organic Anion–Transporting Polypeptide (OATP)–Mediated Drug-Drug Interaction Study between Rosuvastatin and Cyclosporine A in Chimeric Mice with Humanized Liver

Autor: Chise Tateno, Masakazu Kakuni, Masashi Uchida, Eri Sakurada, Yoriko Tajima, Taro Okada, Yutaka Kageyama, Ryoji Hayashi

Publikováno v: Drug Metabolism and Disposition. 46:11-19

The influence of transporters on the pharmacokinetics of drugs is being increasingly recognized, and DDIs via transporters may be a risk factor for adverse events. Cyclosporine A, a strong OATP inhibitor, has been reported to increase the systemic ex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::025aae89cb898e8fbaeb97e5540e2ca7
https://doi.org/10.1124/dmd.117.075994

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TRK-380, a Novel Selective Human β3-Adrenoceptor Agonist, Ameliorates Formalin-induced Pollakiuria in Rats and Carbachol-induced Bladder Contraction in Dogs

Autor: Seiichiro Ozono, Satoru Yoshikawa, Hiroshi Yokokawa, Shoichi Itaba, Yoriko Tajima, Atsushi Otsuka, Ryoji Hayashi, Hidenori Mochizuki, Sayoko Kanie, Ryosuke Kobayashi

Publikováno v: Urology. 82:975.e7-975.e12

Objective To investigate the effects of TRK-380, a selective β 3 -adrenoceptor (β 3 -AR) agonist, on voiding behavior in rats with pollakiuria and on carbachol (CCh)-induced bladder contraction in dogs. Methods The voiding behavior of female Spragu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe06e725733579d85555c3ec2007b809
https://doi.org/10.1016/j.urology.2013.07.016

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