Natural stilbenoids isolated from grapevine exhibiting inhibitory effects against HIV-1 integrase and eukaryote MOS1 transposase in vitro activities.

Autor: Aude Pflieger, Pierre Waffo Teguo, Yorgos Papastamoulis, Stéphane Chaignepain, Frederic Subra, Soundasse Munir, Olivier Delelis, Paul Lesbats, Christina Calmels, Marie-Line Andreola, Jean-Michel Merillon, Corinne Auge-Gouillou, Vincent Parissi

Publikováno v: PLoS ONE, Vol 8, Iss 11, p e81184 (2013)

Polynucleotidyl transferases are enzymes involved in several DNA mobility mechanisms in prokaryotes and eukaryotes. Some of them such as retroviral integrases are crucial for pathogenous processes and are therefore good candidates for therapeutic app

Externí odkaz: https://doaj.org/article/ecc41895c67e45e19fdf74391ff83c35

3D NMR structure of a complex between the amyloid beta peptide (1–40) and the polyphenol ε-viniferin glucoside: Implications in Alzheimer's disease

Autor: Jean-Pierre Monti, Pierre Waffo-Teguo, Tristan Richard, Yorgos Papastamoulis

Publikováno v: Biochimica et Biophysica Acta (BBA) - General Subjects. 1830:5068-5074

Background Alzheimer's disease (AD) is a progressive neurodegenerative disorder. There is a consensus that Aβ is a pathologic agent and that its toxic effects, which are at present incompletely understood, may occur through several potential mechani

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8fd22b03e856fb5813b85792a2b489a
https://doi.org/10.1016/j.bbagen.2013.06.031

Isolation of powerful antioxidants from the medicinal halophyte Limoniastrum guyonianum

Autor: Chedly Abdelly, Pierre Waffo-Teguo, Najla Trabelsi, Samia Oueslati, Jean-Michel Mérillon, Riadh Ksouri, Hanen Falleh, Yorgos Papastamoulis

Publikováno v: Food Chemistry. 135:1419-1424

The antioxidant capacities of the crude extract, aqueous and ethyl acetate partitions of Limoniastrum guyonianum Boiss. (Zita) were investigated in this study. The ethyl acetate phase exhibited a significant antioxidant activity as judged by total an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae8bbab4fbffa54753c9df440ae0ae51
https://doi.org/10.1016/j.foodchem.2012.05.120

Viniphenol A, a complex resveratrol hexamer from Vitis vinifera stalks: structural elucidation and protective effects against amyloid-β-induced toxicity in PC12 cells

Autor: Yorgos Papastamoulis, Alain Badoc, Jean-Pierre Monti, Tristan Richard, Jean-Michel Mérillon, Merian Nassra, Pierre Waffo-Teguo, Dominique Harakat, Stéphanie Krisa

Publikováno v: Journal of natural products. 77(2)

Stilbenes have received much attention during the last two decades following the discovery of resveratrol in wine. Since then, there have been a growing number of papers reporting various biological activities of naturally occurring stilbenes. The ai

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cffb0522591f4bacd353c6dc1b2cb975
https://pubmed.ncbi.nlm.nih.gov/24521157

Phenolics and Their Antifungal Role in Grapevine Wood Decay: Focus on the Botryosphaeriaceae Family

Autor: Tristan Richard, Yorgos Papastamoulis, Jean-Michel Mérillon, Marie-France Corio-Costet, Pierre Waffo-Teguo, Jonathan Bisson, Carole Lambert, Stéphanie Cluzet

Publikováno v: Journal of Agricultural and Food Chemistry
Journal of Agricultural and Food Chemistry, American Chemical Society, 2012, 60 (48), pp.11859-11868. ⟨10.1021/jf303290g⟩

International audience; The interaction between Vitis vinifera and trunk disease fungi requires better understanding. We studied the role of phenolics as possible plant defense compounds in this context. The impact of 24 grapevine phenolic compounds

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f0204195110efd5c6e778545411ec30
https://hal.inrae.fr/hal-02649826