Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Yordan Sbirkov"'
Autor:
Maria Kazakova, Tsvetomira Ivanova, Dorian Dikov, Diana Molander, Kiril Simitchiev, Yordan Sbirkov, Angel M. Dzhambov, Victoria Sarafian
Publikováno v:
Heliyon, Vol 10, Iss 5, Pp e27570- (2024)
Тhe poor prognosis of patients initially diagnosed at an advanced stage of colorectal cancer (CRC) and the heterogeneity within the same tumor stage define the need for additional predictive biomarkers. Tumor buds are proposed as a poor prognostic f
Externí odkaz:
https://doaj.org/article/503b180b5f434b0c93ab82309de9f3bf
Publikováno v:
Biomedicines, Vol 12, Iss 3, p 665 (2024)
Technologies and biomaterials for 3D bioprinting have been developing extremely quickly in the past decade as they hold great potential in tissue engineering. This, together with the possibility to differentiate stem cells of different origin into an
Externí odkaz:
https://doaj.org/article/02e0bffe2b4f4fb4b59be0d377633b24
Autor:
Maria Gevezova, Yordan Sbirkov, Victoria Sarafian, Kitiporn Plaimas, Apichat Suratanee, Michael Maes
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 30, Iss , Pp 100646- (2023)
Background: Despite advances in autism spectrum disorder (ASD) research and the vast genomic, transcriptomic, and proteomic data available, there are still controversies regarding the pathways and molecular signatures underlying the neurodevelopmenta
Externí odkaz:
https://doaj.org/article/090ef83a54c04195b0ba78478111461b
Publikováno v:
Folia Medica, Vol 64, Iss 4, Pp 559-565 (2022)
Neoplastic diseases are a leading cause of death worldwide accounting for 10 million mortalities in 2020. Despite constantly revised and improved therapeutic regimens, the number of fatal cases increases annually. Therefore, better preclinical models
Externí odkaz:
https://doaj.org/article/e4437fbeeab5431891e28cc73db3057a
Autor:
Tsvetomira Ivanova, Yuliia Mariienko, Nikolay Mehterov, Maria Kazakova, Yordan Sbirkov, Krassimira Todorova, Soren Hayrabedyan, Victoria Sarafian
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 9, p 7734 (2023)
At present it is well-defined that autophagy is a fundamental process essential for cell life but its pro-viral and anti-viral role has been stated out with the COVID pandemic. However, viruses in turn have evolved diverse adaptive strategies to cope
Externí odkaz:
https://doaj.org/article/2bff358de7394070a51d93aee008e80a
Autor:
Dobromira Shopova, Antoniya Yaneva, Desislava Bakova, Anna Mihaylova, Petya Kasnakova, Maria Hristozova, Yordan Sbirkov, Victoria Sarafian, Mariya Semerdzhieva
Publikováno v:
Bioengineering, Vol 10, Iss 3, p 287 (2023)
The global development of technologies now enters areas related to human health, with a transition from conventional to personalized medicine that is based to a significant extent on (bio)printing. The goal of this article is to review some of the pu
Externí odkaz:
https://doaj.org/article/cb6fd43e4adc4fe792b10849aae1b8e0
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3378 (2023)
The prognosis for patients with relapsed childhood acute lymphoblastic leukaemia (cALL) remains poor. The main reason for treatment failure is drug resistance, most commonly to glucocorticoids (GCs). The molecular differences between prednisolone-sen
Externí odkaz:
https://doaj.org/article/4707e52a47da4ab3a0896f911c43fc34
Autor:
Yordan Sbirkov, Diana Molander, Clement Milet, Ilia Bodurov, Boyko Atanasov, Radoslav Penkov, Nikolay Belev, Nico Forraz, Colin McGuckin, Victoria Sarafian
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Colorectal cancer (CRC) is the third most common malignancy and has recently moved up to the second leading cause of death among carcinomas. Prognosis, especially for advanced diseases or certain molecular subtypes of CRC, remains poor, which highlig
Externí odkaz:
https://doaj.org/article/0db0c7a3fa2348dda588b1f25c687ba1
Autor:
Yordan Sbirkov, Tsvetomira Ivanova, Hasan Burnusuzov, Kalina Gercheva, Kevin Petrie, Tino Schenk, Victoria Sarafian
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Childhood acute lymphoblastic leukaemia (cALL) accounts for about one third of all paediatric malignancies making it the most common cancer in children. Alterations in tumour cell metabolism were first described nearly a century ago and have been ack
Externí odkaz:
https://doaj.org/article/85e33fa6f63e47e7ba5a4076446c5f00
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 9, p 4657 (2022)
Refractory disease and relapse remain the main causes of cancer therapy failure. Refined risk stratification, treatment regimens and improved early diagnosis and detection of minimal residual disease have increased cure rates in malignancies like chi
Externí odkaz:
https://doaj.org/article/1d4d71e12e634b259c47ea7aedef06ab