Zobrazeno 1 - 10
of 524
pro vyhledávání: '"Yoram Vodovotz"'
Autor:
Jeremy W. Cannon, Danielle S. Gruen, Ruben Zamora, Noah Brostoff, Kelly Hurst, John H. Harn, Fayten El-Dehaibi, Zhi Geng, Rami Namas, Jason L. Sperry, John B. Holcomb, Bryan A. Cotton, Jason J. Nam, Samantha Underwood, Martin A. Schreiber, Kevin K. Chung, Andriy I. Batchinsky, Leopoldo C. Cancio, Andrew J. Benjamin, Erin E. Fox, Steven C. Chang, Andrew P. Cap, Yoram Vodovotz
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-12 (2024)
Abstract Background Optimizing resuscitation to reduce inflammation and organ dysfunction following human trauma-associated hemorrhagic shock is a major clinical hurdle. This is limited by the short duration of pre-clinical studies and the sparsity o
Externí odkaz:
https://doaj.org/article/4ec280b49b694ff292ab1c9cd28a37b5
Autor:
Seth A. Schobel, Eric R. Gann, Desiree Unselt, Scott F. Grey, Felipe A. Lisboa, Meenu M. Upadhyay, Michael Rouse, Simon Tallowin, Nicholas A. Be, Xijun Zhang, Clifton L. Dalgard, Matthew D. Wilkerson, Milos Hauskrecht, Stephen F. Badylak, Ruben Zamora, Yoram Vodovotz, Benjamin K. Potter, Thomas A. Davis, Eric A. Elster
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract A combination of improved body armor, medical transportation, and treatment has led to the increased survival of warfighters from combat extremity injuries predominantly caused by blasts in modern conflicts. Despite advances, a high rate of
Externí odkaz:
https://doaj.org/article/244e583b66a54dd984daaf62225b4196
Publikováno v:
Frontiers in Science, Vol 1 (2024)
As populations worldwide show increasing levels of stress, understanding emerging links among stress, inflammation, cognition, and behavior is vital to human and planetary health. We hypothesize that inflammation is a multiscale driver connecting str
Externí odkaz:
https://doaj.org/article/b568784573454371a18d14f8f1b61972
Autor:
Ashti M. Shah, Ruben Zamora, Derek Barclay, Jinling Yin, Fayten El-Dehaibi, Meghan Addorisio, Tea Tsaava, Aisling Tynan, Kevin Tracey, Sangeeta S. Chavan, Yoram Vodovotz
Publikováno v:
Frontiers in Systems Biology, Vol 4 (2024)
Introduction: The vagus nerve innervates multiple organs, but its role in regulating cross-tissue spread of inflammation is as yet unclear. We hypothesized that the vagus nerve may regulate cross-tissue inflammation via modulation of the putatively n
Externí odkaz:
https://doaj.org/article/496c8d0e4a73410d9d08b91bf0ee8b3b
Autor:
Shayn Peirce-Cottler, Yoram Vodovotz
Publikováno v:
Frontiers in Systems Biology, Vol 4 (2024)
Externí odkaz:
https://doaj.org/article/e0415c677fc640d8b9c259007e4d2dbe
Autor:
Kriti Shah, David A. Geller, Samer Tohme, Michael Antoni, Cramer J. Kallem, Yoram Vodovotz, Rekha Ramanathan, Raam Naveen, MacKenzie Geroni, LaNita Devine, Aarshati Amin, Gauri J. Kiefer, Dan P. Zandberg, Vincent Reyes, Jennifer L. Steel
Publikováno v:
Current Oncology, Vol 30, Iss 10, Pp 8826-8840 (2023)
Objectives: The aims of the study were to (1) describe types of pain in cancer patients, (2) examine the predictors and consequences of pain, (3) investigate the association between type of pain and survival, and (4) examine potential biological medi
Externí odkaz:
https://doaj.org/article/76ca57ffd33a46a9b416d166661d8ac8
Autor:
Fayten El-Dehaibi, Ruben Zamora, Josiah Radder, Jinling Yin, Ashti M. Shah, Rami A. Namas, Michelle Situ, Yanwu Zhao, William Bain, Alison Morris, Bryan J. McVerry, Derek A. Barclay, Timothy R. Billiar, Yingze Zhang, Georgios D. Kitsios, Yoram Vodovotz
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108333- (2023)
Summary: Acute inflammation is heterogeneous in critical illness and predictive of outcome. We hypothesized that genetic variability in novel, yet common, gene variants contributes to this heterogeneity and could stratify patient outcomes. We searche
Externí odkaz:
https://doaj.org/article/e6ad255c4d9d4059bc04de1506bd127e
Autor:
Christopher W. Seymour, MD, MSc, Kelly Lynn Urbanek, MS, Anna Nakayama, Jason N. Kennedy, MS, Rachel Powell, MD, Renã A.S. Robinson, PhD, Kathryn L. Kapp, BS, Timothy R. Billiar, MD, Yoram Vodovotz, PhD, Stacy L. Gelhaus, PhD, Vaughn S. Cooper, PhD, Lu Tang, PhD, Flo Mayr, MD, Katherine M. Reitz, MD, MSc, Christopher Horvat, MD, Nuala J. Meyer, MD, MS, Robert P. Dickson, Derek Angus, MD, Octavia Peck Palmer, PhD
Publikováno v:
Critical Care Explorations, Vol 5, Iss 11, p e0974 (2023)
BACKGROUND:. Sepsis is a common and deadly syndrome, accounting for more than 11 million deaths annually. To mature a deeper understanding of the host and pathogen mechanisms contributing to poor outcomes in sepsis, and thereby possibly inform new th
Externí odkaz:
https://doaj.org/article/7ed111b6ecb34b9ea933120437ef9700
Autor:
Ruben Zamora, Jonathan A. Forsberg, Ashti M. Shah, Desiree Unselt, Scott Grey, Felipe A. Lisboa, Timothy R. Billiar, Seth A. Schobel, Benjamin K. Potter, Eric A. Elster, Yoram Vodovotz
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Dynamic Network Analysis (DyNA) and Dynamic Hypergraphs (DyHyp) were used to define protein-level inflammatory networks at the local (wound effluent) and systemic circulation (serum) levels from 140 active-duty, injured service members (59 w
Externí odkaz:
https://doaj.org/article/23ce7451b34c491b95f17254a7e174d9
Publikováno v:
Frontiers in Systems Biology, Vol 3 (2023)
Largely unknown just a few decades ago, computational systems biology is now a central methodology for biological and medical research. This amazing ascent raises the question of what the community should do next. The article outlines our personal vi
Externí odkaz:
https://doaj.org/article/0eb9e6ca10454b2aa1021805020f4bb4