Zobrazeno 1 - 10
of 136
pro vyhledávání: '"Yoram Nevo"'
Autor:
Lana Meshnik, Dan Bar-Yaacov, Dana Kasztan, Tali Neiger, Tal Cohen, Mor Kishner, Itay Valenci, Sara Dadon, Christopher J. Klein, Jeffery M. Vance, Yoram Nevo, Stephan Züchner, Ofer Ovadia, Dan Mishmar, Anat Ben-Zvi
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-17 (2022)
Abstract Background Mitochondrial DNA (mtDNA) is present at high copy numbers in animal cells, and though characterized by a single haplotype in each individual due to maternal germline inheritance, deleterious mutations and intact mtDNA molecules fr
Externí odkaz:
https://doaj.org/article/b201b8a14eb44511992dfb57115e956e
Autor:
Edward C Smith, Laurie S Conklin, Eric P Hoffman, Paula R Clemens, Jean K Mah, Richard S Finkel, Michela Guglieri, Mar Tulinius, Yoram Nevo, Monique M Ryan, Richard Webster, Diana Castro, Nancy L Kuntz, Laurie Kerchner, Lauren P Morgenroth, Adrienne Arrieta, Maya Shimony, Mark Jaros, Phil Shale, Heather Gordish-Dressman, Laura Hagerty, Utkarsh J Dang, Jesse M Damsker, Benjamin D Schwartz, Laurel J Mengle-Gaw, Craig M McDonald, CINRG VBP15 and DNHS Investigators
Publikováno v:
PLoS Medicine, Vol 17, Iss 9, p e1003222 (2020)
BackgroundTreatment with corticosteroids is recommended for Duchenne muscular dystrophy (DMD) patients to slow the progression of weakness. However, chronic corticosteroid treatment causes significant morbidities. Vamorolone is a first-in-class anti-
Externí odkaz:
https://doaj.org/article/b45ccb68e7754878b721301c83d6bdc1
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 13 (2020)
Muscle stem cells (MuSCs), known as satellite cells (SCs) have an incredible ability to regenerate, which enables the maintenance and growth of muscle tissue. In response to damaging stimuli, SCs are activated, proliferate, differentiate, and fuse to
Externí odkaz:
https://doaj.org/article/bb9a1391407444eea828d6819812701d
Publikováno v:
Pharmaceutics, Vol 13, Iss 2, p 185 (2021)
We previously reported the development of a novel formulation of an ultra-long-acting local anesthetic based on bupivacaine encapsulated in large multivesicular liposomes (Bupisomes) embedded in hydrogel. This formulation (Bupigel) prolonged bupivaca
Externí odkaz:
https://doaj.org/article/d7dcb06054fe4e68844feaeb8306ccc4
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 12, p 4511 (2020)
Duchenne muscular dystrophy (DMD) is a severe muscle wasting disease typically caused by protein-truncating mutations that preclude synthesis of a functional dystrophin. Exonic deletions are the most common type of DMD lesion, however, whole exon dup
Externí odkaz:
https://doaj.org/article/d8aa94d9c05d4327902ca365603ed2a6
Autor:
Tehila Mizrachi, Livnat Brill, Malcolm Rabie, Yoram Nevo, Yakov Fellig, Mayan Zur, Dimitrios Karussis, Oded Abramsky, Talma Brenner, Adi Vaknin-Dembinsky
Publikováno v:
Journal of Immunology Research, Vol 2018 (2018)
Neuromyelitis optica (NMO) and myasthenia gravis (MG) are autoimmune diseases mediated by autoantibodies against either aquaporin 4 (AQP4) or acetylcholine receptor (AChR), respectively. Recently, we and others have reported an increased prevalence o
Externí odkaz:
https://doaj.org/article/403e8ae6eaa84e13b8a97379aea65d94
Autor:
Sitvanit Haziza, Roberta Magnani, Dima Lan, Omer Keinan, Ann Saada, Eli Hershkovitz, Nurit Yanay, Yoram Cohen, Yoram Nevo, Robert L Houtz, Val C Sheffield, Hava Golan, Ruti Parvari
Publikováno v:
PLoS Genetics, Vol 11, Iss 8, p e1005388 (2015)
Calmodulin lysine methyl transferase (CaM KMT) is ubiquitously expressed and highly conserved from plants to vertebrates. CaM is frequently trimethylated at Lys-115, however, the role of CaM methylation in vertebrates has not been studied. CaM KMT wa
Externí odkaz:
https://doaj.org/article/7de9c4d4105a41819070d84ef5f1387c
Autor:
Ruben Attali, Sharon Aharoni, Susan Treves, Ori Rokach, Michal Becker Cohen, Yakov Fellig, Rachel Straussberg, Talya Dor, Muhannad Daana, Stella Mitrani-Rosenbaum, Yoram Nevo
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69296 (2013)
We describe an autosomal recessive heterogeneous congenital myopathy in a large consanguineous family. The disease is characterized by variable severity, progressive course in 3 of 4 patients, myopathic face without ophthalmoplegia and proximal muscl
Externí odkaz:
https://doaj.org/article/02dcdff8a06848c0afb90b230e57ca0a
Autor:
Yoram Nevo, Shlomit Aga-Mizrachi, Edva Elmakayes, Nurit Yanay, Keren Ettinger, Moran Elbaz, Zivia Brunschwig, Oshrat Dadush, Galit Elad-Sfadia, Roni Haklai, Yoel Kloog, Joab Chapman, Shimon Reif
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e18049 (2011)
The Ras superfamily of guanosine-triphosphate (GTP)-binding proteins regulates a diverse spectrum of intracellular processes involved in inflammation and fibrosis. Farnesythiosalicylic acid (FTS) is a unique and potent Ras inhibitor which decreased i
Externí odkaz:
https://doaj.org/article/3e0e0395acd2471d8f1ed6eb1990aded
Autor:
Itay Tokatly Latzer, Liora Sagi, Revital Lavi, Sharon Aharoni, Jacob Bistritzer, Iris Noyman, Mira Ginsburg, Angela Lev-Or, Sharona Katzenellenbogen, Yoram Nevo, Aviva Fattal-Valevski
Publikováno v:
Pediatric Neurology. 144:60-68