Výsledky vyhledávání - "Yoony Y.J. Gent"

Regulation of Treg functionality by acetylation-mediated Foxp3 protein stabilization

Autor: Jeffrey M. Beekman, Teun Guichelaar, Paul J. Coffer, Berent J. Prakken, Yoony Y.J. Gent, DirkJan Hijnen, Eric Kalkhoven, Yvonne Vercoulen, Jorg van Loosdregt, Arjan B. Brenkman, Olivier van Beekum, Tuna Mutis

Publikováno v: Van Loosdregt, J, Vercoulen, Y, Guichelaar, T, Gent, Y Y J, Beekman, J M, Van Beekum, O, Brenkman, A B, Hijnen, D J, Mutis, T, Kalkhoven, E, Prakken, B J & Coffer, P J 2010, ' Regulation of Treg functionality by acetylation-mediated Foxp3 protein stabilization ', Blood, vol. 115, no. 5, pp. 965-974 . https://doi.org/10.1182/blood-2009-02-207118
Blood, 115(5), 965-974. American Society of Hematology
Blood, 115(5), 965. American Society of Hematology

Regulatory T cells (Tregs) are a specific subset of lymphocytes that are critical for the maintenance of self-tolerance. Expression levels of the transcription factor Foxp3 have been causally associated with Treg differentiation and function. Recent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bbd3550384621a5e50b890f8c7ff7fb
https://doi.org/10.1182/blood-2009-02-207118

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Amyloid-β-stimulated plasminogen activation by tissue-type plasminogen activator results in processing of neuroendocrine factors

Autor: Albert J. R. Heck, Emile E. Voest, Yoony Y.J. Gent, Martijn F.B.G. Gebbink, Edwin P. Romijn, Onno Kranenburg

Publikováno v: Neuroscience. 131:877-886

Alzheimer's disease brain is characterized by the abundant presence of amyloid deposits. Accumulation of the major constituent of these deposits, amyloid-beta (Abeta), has been associated with decreased neurotransmission, increased neuronal cell deat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9b8c1dfc8edbcde807df7141ab51e7f
https://doi.org/10.1016/j.neuroscience.2004.11.044

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CD8+ T cells in the lesional skin of atopic dermatitis and psoriasis patients are an important source of IFN-γ, IL-13, IL-17 and IL-22

Autor: Rachael A. Clark, Thomas S. Kupper, Yoony Y.J. Gent, Carla A.F.M. Bruijnzeel-Koomen, DirkJan Hijnen, Scott J.P. Beijn, Edward F. Knol, Barbara Giovannone

Although CD4(+) T cells are known to contribute to the pathology of atopic dermatitis (AD) and psoriasis, the role of CD8(+) T cells in these diseases remains poorly characterized. The aim of this study was to characterize the cytokine production of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d485a4e5b1d22df055e9ead70f98999
https://europepmc.org/articles/PMC3835628/

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Beta-amyloid (Abeta) causes detachment of N1E-115 neuroblastoma cells by acting as a scaffold for cell-associated plasminogen activation

Autor: George Posthuma, Emile E. Voest, Martijn F.B.G. Gebbink, Onno Kranenburg, Barend Bouma, Yoony Y.J. Gent, Rakez Kayed, Bettina Schiks, C. J. M. Aarsman

Publikováno v: Molecular and cellular neurosciences. 28(3)

A major component of neuritic plaques in brain tissue of Alzheimer's disease patients is the beta-amyloid peptide (Abeta). Accumulation of Abeta has been associated with increased neuronal cell death and cognitive decline. We have previously shown th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b450bee4683fe59c67d3d20b672f29c
https://pubmed.ncbi.nlm.nih.gov/15737740

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