Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Yoonjung Shim"'
Autor:
Trevor van Eeuwen, Yoonjung Shim, Hee Jong Kim, Tingting Zhao, Shrabani Basu, Benjamin A. Garcia, Craig D. Kaplan, Jung-Hyun Min, Kenji Murakami
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
The conserved eukaryotic nucleotide excision repair (NER) pathway protects the genome from a wide variety of environmentally induced DNA lesions. Here, the authors provide insights into how NER is initiated on lesions by determining the cryo-EM struc
Externí odkaz:
https://doaj.org/article/d50d4da2dfcb426987c2cc95413c64ea
Autor:
Yoonjung Shim, Shrabani Basu, Kenji Murakami, Trevor van Eeuwen, Craig D. Kaplan, Tingting Zhao, Benjamin A. Garcia, Jung Hyun Min, Hee Jong Kim
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Nature Communications
Nature Communications
The versatile nucleotide excision repair (NER) pathway initiates as the XPC–RAD23B–CETN2 complex first recognizes DNA lesions from the genomic DNA and recruits the general transcription factor complex, TFIIH, for subsequent lesion verification. H
Autor:
Suse Broyde, Hong Mu, Nicholas E. Geacintov, Yuan Cho Lee, Jung Hyun Min, Katie M. Feher, Yoonjung Shim, Vladimir Shafirovich, Alexander Kolbanovskiy, Alexander Durandin
Publikováno v:
DNA Repair (Amst)
The Nucleotide Excision Repair (NER) mechanism removes a wide spectrum of structurally different lesions that critically depend on the binding of the DNA damage sensing NER factor XPC-RAD23B (XPC) to the lesions. The bulky mutagenic benzo[a]pyrene di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c418f3d027699d75c8135dd89415bb7
https://europepmc.org/articles/PMC8423485/
https://europepmc.org/articles/PMC8423485/
Autor:
Wonhwa Cho, Shu-Lin Liu, Yoonjung Shim, Liang Wei Gong, Jin Zhang, Zhi-Gang Wang, Yusi Hu, Xin Zhou, Yao Xin, Jung Hyun Min, Sukhamoy Gorai, Nissim Hay, Indira Singaram
Publikováno v:
Molecular cell. 71(6)
Activation of class I phosphatidylinositol 3-kinase (PI3K) leads to formation of phosphatidylinositol-3,4,5-trisphophate (PIP3) and phosphatidylinositol-3,4-bisphophate (PI34P2), which spatiotemporally coordinate and regulate a myriad of cellular pro
Autor:
Alvin W. Hung, John Liang Kuan Wee, Yvonne Tan, Jianhe Peng, Jung Hyun Min, Rong Li, Wei Guang Seetoh, Horst Flotow, Anna Ngo, Liling Wu, Ernesto Guccione, Joma Joy, Xiaoying Koh-Stenta, Yoonjung Shim, Jing Cao, Jeffrey Hill, Umayal Lakshmanan, Perlyn Zekui Kwek, Anders Poulsen
Publikováno v:
Biochemical Journal. 461:323-334
PRDM proteins have emerged as important regulators of disease and developmental processes. To gain insight into the mechanistic actions of the PRDM family, we have performed comprehensive characterization of a prototype member protein, the histone me
Autor:
Nicholas E. Geacintov, Kent D. Sugden, Marina Kolbanovskiy, Brooke D. Martin, Jung Hyun Min, Zhi Liu, Konstantin Kropachev, Vladimir Shafirovich, Thomas Anderson, Yoonjung Shim, Xuejing Chen
The well known biomarker of oxidative stress, 8-oxo-7,8-dihydroguanine, is more susceptible to further oxidation than the parent guanine base and can be oxidatively transformed to the genotoxic spiroiminodihydantoin (Sp) and 5-guanidinohydantoin (Gh)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3a2583bbaeeb9fccfc6ca2f2f994263
https://europepmc.org/articles/PMC4777862/
https://europepmc.org/articles/PMC4777862/
Autor:
Yoonjung Shim, Xuejing Chen, Guanqun Zheng, Beomseok Park, Anjum Ansari, Lili Liu, Bennett Van Houten, Youngchang Kim, Jung Hyun Min, Yogambigai Velmurugu, Chuan He
Publikováno v:
Nature Communications
The xeroderma pigmentosum C (XPC) complex initiates nucleotide excision repair by recognizing DNA lesions before recruiting downstream factors. How XPC detects structurally diverse lesions embedded within normal DNA is unknown. Here we present a crys
Histone octamers are the basic building blocks of chromatin and are platforms for diverse genetic mechanisms. We report a simple method for preparing recombinant histone octamers by overexpressing all four histones from a single polycistronic vector
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28c6da281fd433ce8ca34d6388d19fae
https://europepmc.org/articles/PMC3412673/
https://europepmc.org/articles/PMC3412673/
Autor:
Xiaoying KOH-STENTA, JOY, Joma, POULSEN, Anders, Rong LI, Yvonne TAN, Yoonjung SHIM, Jung-Hyun MIN, Liling WU, NGO, Anna, Jianhe PENG, Wei Guang SEETOH, Jing CAO, John Liang Kuan WEE, KWEK, Perlyn Zekui, Alvin HUNG, LAKSHMANAN, Umayal, FLOTOW, Horst, GUCCIONE, Ernesto, HILL, Jeffrey
Publikováno v:
Biochemical Journal; 7/15/2014, Vol. 461 Issue 2, p323-334, 22p