Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Yoonji Jung"'
Autor:
Eunah Kim, Andrea Annibal, Yujin Lee, Hae-Eun H. Park, Seokjin Ham, Dae-Eun Jeong, Younghun Kim, Sangsoon Park, Sujeong Kwon, Yoonji Jung, JiSoo Park, Sieun S. Kim, Adam Antebi, Seung-Jae V. Lee
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Accumulating evidence indicates that mitochondria play crucial roles in immunity. However, the role of the mitochondrial Krebs cycle in immunity remains largely unknown, in particular at the organism level. Here we show that mitochondrial ac
Externí odkaz:
https://doaj.org/article/76ceadb6d9c14ef9a0dd85f7da8d2b66
Autor:
Dongyeop Lee, Seon Woo A An, Yoonji Jung, Yasuyo Yamaoka, Youngjae Ryu, Grace Ying Shyen Goh, Arshia Beigi, Jae-Seong Yang, Gyoo Yeol Jung, Dengke K Ma, Chang Man Ha, Stefan Taubert, Youngsook Lee, Seung-Jae V Lee
Publikováno v:
PLoS Biology, Vol 17, Iss 8, p e3000415 (2019)
Low temperatures delay aging and promote longevity in many organisms. However, the metabolic and homeostatic aspects of low-temperature-induced longevity remain poorly understood. Here, we show that lipid homeostasis regulated by Caenorhabditis elega
Externí odkaz:
https://doaj.org/article/a87c878b580e45cd83bfa66a2646930b
Autor:
Sangsoon Park, Yoonji Jung, Seon Woo A. An, Heehwa G. Son, Wooseon Hwang, Dongyeop Lee, Murat Artan, Hae-Eun H. Park, Dae-Eun Jeong, Yujin Lee, Seung-Jae V. Lee
Publikováno v:
F1000Research, Vol 6 (2017)
Background: α-arrestins are a family of proteins that are implicated in multiple biological processes, including metabolism and receptor desensitization. Methods: Here, we sought to examine the roles of α-arrestins in the longevity of Caenorhabditi
Externí odkaz:
https://doaj.org/article/d778e6352493489fae62592a3b9798f3
Autor:
Sangsoon Park, Yoonji Jung, Seon Woo A. An, Heehwa G. Son, Wooseon Hwang, Dongyeop Lee, Murat Artan, Hae-Eun H. Park, Dae-Eun Jeong, Yujin Lee, Seung-Jae V. Lee
Publikováno v:
F1000Research, Vol 6 (2017)
Background: α-arrestins are a family of proteins that are implicated in multiple biological processes, including metabolism and receptor desensitization. Methods: Here, we sought to examine the roles of α-arrestins in the longevity of Caenorhabditi
Externí odkaz:
https://doaj.org/article/0e2ea24daffb419282d20c588166ab9d
Autor:
Seokjin Ham, Sieun S. Kim, Sangsoon Park, Eun Ji E. Kim, Sujeong Kwon, Hae-Eun H. Park, Yoonji Jung, Seung-Jae V. Lee
Publikováno v:
Genome Research. 32:2003-2014
Aging is associated with changes in a variety of biological processes at the transcriptomic level, including gene expression. Two types of aging occur during a lifetime: chronological and physiological aging. However, dissecting the difference betwee
Autor:
Seokjin, Ham, Sieun S, Kim, Sangsoon, Park, Eun Ji E, Kim, Sujeong, Kwon, Hae-Eun H, Park, Yoonji, Jung, Seung-Jae V, Lee
Publikováno v:
Genome research.
Aging is associated with changes in a variety of biological processes at the transcriptomic level, including gene expression. Two types of aging occur during life time: chronological and physiological aging. However, dissecting the difference between
Autor:
Dongyeop Lee, Hyun-Jun Nam, Chanhee Kang, Jooyeon Sohn, Malene Hansen, Linnea M Adams, Yujin Lee, Eun Ji Kim, Seung-Yeol Park, Murat Artan, Dae-Eun Jeong, Dong Jin Moon, Wooseon Hwang, Seung-Jae Lee, Joo-Yeon Yoo, Mihwa Seo, Jeonghun Yeom, Yoonji Jung, Ozlem Altintas, Youngjae Ryu, Sang Ki Park, Cheolju Lee, Keunhee Seo, Sanguk Kim, Chang Man Ha, Seong Kyu Han, Nari Kim, Ara B. Hwang, Sungeun Ju
Publikováno v:
Science Advances
Description
MON-2, which mediates Golgi-endosome trafficking, mediates mitochondrial inhibition–induced longevity by enhancing autophagy.
The Golgi apparatus plays a central role in trafficking cargoes such as proteins and lipids. Defects
MON-2, which mediates Golgi-endosome trafficking, mediates mitochondrial inhibition–induced longevity by enhancing autophagy.
The Golgi apparatus plays a central role in trafficking cargoes such as proteins and lipids. Defects
Autor:
Sangsoon Park, Yunji Choi, Seung-Jae Lee, Murat Artan, Kyuhyung Kim, Dae-Eun Jeong, Hae-Eun H. Park, Yoonji Jung, Heehwa G. Son, Sieun S. Kim, Jin I. Lee
Publikováno v:
Aging Cell
Dietary restriction extends lifespan in various organisms by reducing the levels of both nutrients and non‐nutritional food‐derived cues. However, the identity of specific food‐derived chemical cues that alter lifespan remains unclear. Here, we
Autor:
Yujin Lee, Yoonji Jung, Seokjin Ham, Hae-Eun H. Park, Sujeong Kwon, Wooseon Hwang, Seung-Jae Lee, Jasmine Ashraf, Coleen T. Murphy, Dae-Eun Jeong
Publikováno v:
The Journal of Cell Biology
Immunosenescence, or immune aging, is a hallmark of aging. This study shows that inhibition of insulin/IGF-1 receptor reverses immunosenescence in the roundworm Caenorhabditis elegans through a feedback circuit comprising FOXO, HSF-1, and bZIP transc
Autor:
Ozlem Altintas, Dongyeop Lee, Sangsoon Park, Heehwa G. Son, Seung-Jae Lee, Yujin Lee, Wooseon Hwang, Seon Woo A. An, Seokjin Ham, Murat Artan, Sujeong Kwon, Mihwa Seo, Eun Ji Kim, Yasuyo Yamaoka, Dae-Eun Jeong, Yoonji Jung, Hae-Eun H. Park
Publikováno v:
Aging Cell
Excessive glucose causes various diseases and decreases lifespan by altering metabolic processes, but underlying mechanisms remain incompletely understood. Here, we show that Lipin 1/LPIN‐1, a phosphatidic acid phosphatase and a putative transcript