A Case Series of Paediatric Living Donor Liver Transplant in University of Malaya Medical Centre (UMMC): Indications, Perioperative Management and our Learning Points.

Autor: M. DAMANHURI, I. RASHID, II SHARIFFUDDIN, NG TY, KEVIN WS NG, CHAW SH, NG RT, YOONG BK, LOH PS

Publikováno v: Medicine & Health (Universiti Kebangsaan Malaysia); 2021 Supplement, Vol. 16, p101-101, 1p

A genomic enhancer signature associates with hepatocellular carcinoma prognosis.

Autor: Jeon AJ; Program in Clinical and Translational Liver Cancer Research, Division of Medical Science, National Cancer Center Singapore, Singapore., Anene-Nzelu CG; Cardiovascular Disease Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Montreal Heart Institute, Montreal, Quebec, Canada.; Department of Medicine, University of Montreal, Quebec, Canada., Teo YY; Program in Clinical and Translational Liver Cancer Research, Division of Medical Science, National Cancer Center Singapore, Singapore., Chong SL; Program in Clinical and Translational Liver Cancer Research, Division of Medical Science, National Cancer Center Singapore, Singapore., Sekar K; Program in Clinical and Translational Liver Cancer Research, Division of Medical Science, National Cancer Center Singapore, Singapore., Wu L; Program in Clinical and Translational Liver Cancer Research, Division of Medical Science, National Cancer Center Singapore, Singapore., Chew SC; Program in Clinical and Translational Liver Cancer Research, Division of Medical Science, National Cancer Center Singapore, Singapore., Chen J; Genome Institute of Singapore, Agency for Science, Technology and Research (A∗STAR), Singapore., Kendarsari RI; Genome Institute of Singapore, Agency for Science, Technology and Research (A∗STAR), Singapore., Lai H; Genome Institute of Singapore, Agency for Science, Technology and Research (A∗STAR), Singapore., Ling WH; Program in Clinical and Translational Liver Cancer Research, Division of Medical Science, National Cancer Center Singapore, Singapore., Kaya NA; Genome Institute of Singapore, Agency for Science, Technology and Research (A∗STAR), Singapore., Lim JQ; Genome Institute of Singapore, Agency for Science, Technology and Research (A∗STAR), Singapore., Chung AYF; Department of Hepatopancreatobiliary and Transplant Surgery, National Cancer Centre Singapore and Singapore General Hospital, Singapore.; Academic Clinical Programme for Surgery, Duke-NUS Medical School, Singapore., Cheow PC; Department of Hepatopancreatobiliary and Transplant Surgery, National Cancer Centre Singapore and Singapore General Hospital, Singapore.; Academic Clinical Programme for Surgery, Duke-NUS Medical School, Singapore., Kam JH; Department of Hepatopancreatobiliary and Transplant Surgery, National Cancer Centre Singapore and Singapore General Hospital, Singapore.; Academic Clinical Programme for Surgery, Duke-NUS Medical School, Singapore., Madhavan K; Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, University Surgical Cluster, National University Health System, Singapore., Kow A; Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, University Surgical Cluster, National University Health System, Singapore., Ganpathi IS; Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, University Surgical Cluster, National University Health System, Singapore., Lim TKH; Department of Anatomical Pathology, Singapore General Hospital, Singapore., Leow WQ; Department of Anatomical Pathology, Singapore General Hospital, Singapore., Loong S; Department of Anatomical Pathology, Singapore General Hospital, Singapore., Loh TJ; Department of Anatomical Pathology, Singapore General Hospital, Singapore., Wan WK; Department of Anatomical Pathology, Singapore General Hospital, Singapore., Soon GST; Department of Pathology, National University Hospital, Singapore., Pang YH; Department of Pathology, National University Hospital, Singapore., Yoong BK; Department of Surgery, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia., Bee-Lan Ong D; Department of Surgery, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia., Lim J; Department of Surgery, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia., de Villa VH; Department of Surgery and Center for Liver Health and Transplantation, The Medical City, Pasig City, Philippines., Dela Cruz RD; Department of Laboratory Medicine and Pathology, The Medical City, Pasig City, Philippines., Chanwat R; Hepato-Pancreato-Biliary Surgery Unit, Department of Surgery, National Cancer Institute, Bangkok, Thailand., Thammasiri J; Division of Pathology, National Cancer Institute, Thailand., Bonney GK; Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, University Surgical Cluster, National University Health System, Singapore., Goh BKP; Department of Hepatopancreatobiliary and Transplant Surgery, National Cancer Centre Singapore and Singapore General Hospital, Singapore.; Academic Clinical Programme for Surgery, Duke-NUS Medical School, Singapore., Foo RSY; Cardiovascular Disease Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Genome Institute of Singapore, Agency for Science, Technology and Research (A∗STAR), Singapore.; Cardiovascular Research Institute, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Chow PK; Program in Clinical and Translational Liver Cancer Research, Division of Medical Science, National Cancer Center Singapore, Singapore.; Department of Hepatopancreatobiliary and Transplant Surgery, National Cancer Centre Singapore and Singapore General Hospital, Singapore.; Academic Clinical Programme for Surgery, Duke-NUS Medical School, Singapore.

Publikováno v: JHEP reports : innovation in hepatology [JHEP Rep] 2023 Feb 26; Vol. 5 (6), pp. 100715. Date of Electronic Publication: 2023 Feb 26 (Print Publication: 2023).

Pan-cancer pervasive upregulation of 3' UTR splicing drives tumourigenesis.

Autor: Chan JJ; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore., Zhang B; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.; Computer Science Program, Computer, Electrical and Mathematical Sciences and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia.; KAUST Computational Bioscience Research Center, King Abdullah University of Science and Technology, Thuwal, Saudi Arabia., Chew XH; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore., Salhi A; Computer Science Program, Computer, Electrical and Mathematical Sciences and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia.; KAUST Computational Bioscience Research Center, King Abdullah University of Science and Technology, Thuwal, Saudi Arabia., Kwok ZH; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Boston University, Boston, MA, USA., Lim CY; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore., Desi N; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore., Subramaniam N; A*STAR Skin Research Labs and Skin Research Institute of Singapore, A*STAR, Immunos, Singapore, Singapore., Siemens A; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.; The University of British Columbia, Vancouver, British Columbia, Canada., Kinanti T; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore., Ong S; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore., Sanchez-Mejias A; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.; Integra Therapeutics S.L., Barcelona, Spain., Ly PT; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore., An O; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore., Sundar R; Department of Haematology-Oncology, National University Cancer Institute of Singapore, National University Health System, Singapore, Singapore.; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; The N.1 Institute for Health, National University of Singapore, Singapore, Singapore., Fan X; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore., Wang S; Department of Pathology, National University Health System, Singapore, Singapore., Siew BE; Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Lee KC; Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Division of Colorectal Surgery, University Surgical Cluster, National University Health System, Singapore, Singapore., Chong CS; Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Division of Colorectal Surgery, University Surgical Cluster, National University Health System, Singapore, Singapore., Lieske B; Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Division of Colorectal Surgery, University Surgical Cluster, National University Health System, Singapore, Singapore., Cheong WK; Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Division of Colorectal Surgery, University Surgical Cluster, National University Health System, Singapore, Singapore., Goh Y; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore., Fam WN; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore., Ooi MG; Department of Haematology-Oncology, National University Cancer Institute of Singapore, National University Health System, Singapore, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Koh BTH; Department of Orthopaedic Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Iyer SG; Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Division of Hepatobiliary & Pancreatic Surgery, University Surgical Cluster, National University Health System, Singapore, Singapore., Ling WH; Program in Clinical and Translational Liver Cancer Research, National Cancer Center Singapore, Singapore, Singapore., Chen J; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Yoong BK; Department of Surgery, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia., Chanwat R; Hepato-Pancreato-Biliary Surgery Unit, Department of Surgery, National Cancer Institute, Bangkok, Thailand., Bonney GK; Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Division of Hepatobiliary & Pancreatic Surgery, University Surgical Cluster, National University Health System, Singapore, Singapore., Goh BKP; Department of Hepatopancreatobiliary and Transplantation Surgery, Singapore General Hospital and National Cancer Center Singapore, Singapore, Singapore., Zhai W; Program in Clinical and Translational Liver Cancer Research, National Cancer Center Singapore, Singapore, Singapore.; Key Laboratory of Zoological Systematics and Evolution, Institute of Zoology, Chinese Academy of Sciences, Beijing, China., Fullwood MJ; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore.; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Wang W; Department of Orthopaedic Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Tan KK; Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Division of Colorectal Surgery, University Surgical Cluster, National University Health System, Singapore, Singapore., Chng WJ; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.; Department of Haematology-Oncology, National University Cancer Institute of Singapore, National University Health System, Singapore, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Dan YY; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Pitt JJ; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.; NUS Centre for Cancer Research, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Roca X; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore., Guccione E; Center for Therapeutics Discovery, Department of Oncological Sciences and Pharmacological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York City, NY, USA., Vardy LA; A*STAR Skin Research Labs and Skin Research Institute of Singapore, A*STAR, Immunos, Singapore, Singapore., Chen L; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.; Department of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Gao X; Computer Science Program, Computer, Electrical and Mathematical Sciences and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia.; KAUST Computational Bioscience Research Center, King Abdullah University of Science and Technology, Thuwal, Saudi Arabia.; BioMap, Beijing, China., Chow PKH; Program in Clinical and Translational Liver Cancer Research, National Cancer Center Singapore, Singapore, Singapore.; Department of Hepatopancreatobiliary and Transplantation Surgery, Singapore General Hospital and National Cancer Center Singapore, Singapore, Singapore.; Academic Clinical Programme for Surgery, SingHealth Duke-NUS Academic Medical Centre (AMC), Singapore, Singapore., Yang H; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore., Tay Y; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore. yvonnetay@nus.edu.sg.; NUS Centre for Cancer Research, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. yvonnetay@nus.edu.sg.; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. yvonnetay@nus.edu.sg.

Publikováno v: Nature cell biology [Nat Cell Biol] 2022 Jun; Vol. 24 (6), pp. 928-939. Date of Electronic Publication: 2022 May 26.

Application of Proteomics in Pancreatic Ductal Adenocarcinoma Biomarker Investigations: A Review.

Autor: Vellan CJ; Department of Molecular Medicine, Faculty of Medicine, Universiti Malaya, Kuala Lumpur 50603, Malaysia., Jayapalan JJ; Department of Molecular Medicine, Faculty of Medicine, Universiti Malaya, Kuala Lumpur 50603, Malaysia.; University of Malaya Centre for Proteomics Research (UMCPR), Universiti Malaya, Kuala Lumpur 50603, Malaysia., Yoong BK; Department of Surgery, Faculty of Medicine, Universiti Malaya, Kuala Lumpur 50603, Malaysia., Abdul-Aziz A; Department of Molecular Medicine, Faculty of Medicine, Universiti Malaya, Kuala Lumpur 50603, Malaysia., Mat-Junit S; Department of Molecular Medicine, Faculty of Medicine, Universiti Malaya, Kuala Lumpur 50603, Malaysia., Subramanian P; Department of Biochemistry and Biotechnology, Annamalai University, Chidambaram 608002, Tamil Nadu, India.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2022 Feb 14; Vol. 23 (4). Date of Electronic Publication: 2022 Feb 14.

Dynamic phenotypic heterogeneity and the evolution of multiple RNA subtypes in hepatocellular carcinoma: the PLANET study.

Autor: Zhai W; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore 138672, Singapore., Lai H; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore 138672, Singapore., Kaya NA; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore 138672, Singapore., Chen J; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore 138672, Singapore., Yang H; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore 138672, Singapore., Lu B; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore 138672, Singapore., Lim JQ; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore 138672, Singapore., Ma S; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore 138672, Singapore., Chew SC; Division of Surgery and Surgical Oncology, National Cancer Centre, Singapore 169610, Singapore., Chua KP; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore 138672, Singapore., Alvarez JJS; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore 138672, Singapore., Chen PJ; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore 138672, Singapore., Chang MM; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore 138672, Singapore., Wu L; Division of Surgery and Surgical Oncology, National Cancer Centre, Singapore 169610, Singapore., Goh BKP; Department of Hepato-Pancreato-Biliary and Transplant Surgery, Singapore General Hospital, Singapore 169608, Singapore., Chung AY; Department of Hepato-Pancreato-Biliary and Transplant Surgery, Singapore General Hospital, Singapore 169608, Singapore., Chan CY; Department of Hepato-Pancreato-Biliary and Transplant Surgery, Singapore General Hospital, Singapore 169608, Singapore., Cheow PC; Department of Hepato-Pancreato-Biliary and Transplant Surgery, Singapore General Hospital, Singapore 169608, Singapore., Lee SY; Department of Hepato-Pancreato-Biliary and Transplant Surgery, Singapore General Hospital, Singapore 169608, Singapore., Kam JH; Department of Hepato-Pancreato-Biliary and Transplant Surgery, Singapore General Hospital, Singapore 169608, Singapore., Kow AW; Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, University Surgical Cluster, National University Health System, Singapore 119228, Singapore., Ganpathi IS; Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, University Surgical Cluster, National University Health System, Singapore 119228, Singapore., Chanwat R; Hepato-Pancreato-Biliary Surgery Unit, Department of Surgery, National Cancer Institute, Bangkok 10310, Thailand., Thammasiri J; Division of Pathology, National Cancer Institute, Bangkok 10400, Thailand., Yoong BK; Department of Surgery, Faculty of Medicine, University of Malaya, Kuala Lumpur 59100, Malaysia., Ong DB; Department of Surgery, Faculty of Medicine, University of Malaya, Kuala Lumpur 59100, Malaysia., de Villa VH; Department of Surgery and Center for Liver Disease Management and Transplantation, The Medical City, Pasig City, Metro Manila, Philippines., Dela Cruz RD; Department of Laboratories, The Medical City, Pasig City, Metro Manila, Philippines., Loh TJ; Department of Pathology, Singapore General Hospital, Singapore 169608, Singapore., Wan WK; Department of Pathology, Singapore General Hospital, Singapore 169608, Singapore., Zeng Z; Institute for Infocomm Research, ASTAR, Singapore 138632, Singapore., Skanderup AJ; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore 138672, Singapore., Pang YH; Department of Pathology, National University Health System, Singapore 119228, Singapore., Madhavan K; Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, University Surgical Cluster, National University Health System, Singapore 119228, Singapore., Lim TK; Department of Pathology, Singapore General Hospital, Singapore 169608, Singapore., Bonney G; Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, University Surgical Cluster, National University Health System, Singapore 119228, Singapore., Leow WQ; Department of Pathology, Singapore General Hospital, Singapore 169608, Singapore., Chew V; Translational Immunology Institute (TII), SingHealth Duke-NUS Academic Medical Centre, Singapore 168753, Singapore., Dan YY; Division of Gastroenterology and Hepatology, University Medicine Cluster, National University Hospital, Singapore 119228, Singapore., Tam WL; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore 138672, Singapore., Toh HC; Division of Medical Oncology, National Cancer Center Singapore, Singapore 169610, Singapore., Foo RS; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore 138672, Singapore., Chow PK; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore 138672, Singapore.

Publikováno v: National science review [Natl Sci Rev] 2021 Oct 29; Vol. 9 (3), pp. nwab192. Date of Electronic Publication: 2021 Oct 29 (Print Publication: 2022).