Zobrazeno 1 - 10
of 146
pro vyhledávání: '"Yoon-Kyu Song"'
Publikováno v:
Pharmaceutics, Vol 16, Iss 4, p 566 (2024)
Post-operative chemotherapy is still required for the treatment of glioblastoma (GBM), for which nanocarrier-based drug delivery has been identified as one of the most effective methods. However, the blood-brain barrier (BBB) and non-specific deliver
Externí odkaz:
https://doaj.org/article/b2ba0b09987d4e36ac26726dca227852
A trafficking motif alters GEVI activity implicating persistent protein interactions at the membrane
Publikováno v:
Biophysical Reports, Vol 2, Iss 2, Pp 100047- (2022)
Efficient plasma-membrane expression is critical for genetically encoded voltage indicators (GEVIs). To improve the plasma-membrane expression, we introduced multiple combinations of plasma-membrane trafficking motifs at different positions to member
Externí odkaz:
https://doaj.org/article/f71cf6505a21431f9314564ac9675244
Autor:
Jungwoo Jang, Changhoon Baek, Sunhyo Kim, Tae-Kyeong Lee, Gwang-Jin Choi, Shinyong Shim, Seunghyeon Yun, Younginha Jung, Chae-Eun Lee, Seunghyung Ko, Kangmoon Seo, Jong-Mo Seo, Moo-Ho Won, Sung J. Kim, Yoon-Kyu Song
Publikováno v:
Micromachines, Vol 12, Iss 7, p 788 (2021)
A number of research attempts to understand and modulate sensory and motor skills that are beyond the capability of humans have been underway. They have mainly been expounded in rodent models, where numerous reports of controlling movement to reach t
Externí odkaz:
https://doaj.org/article/e7adc747ac92495fa50b4f57c0e5364c
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Abstract An improved genetically encoded voltage indicator (GEVI) was achieved by altering the charge composition of the region linking the voltage-sensing domain of the GEVI to a pH-sensitive fluorescent protein. Negatively charged linker segments r
Externí odkaz:
https://doaj.org/article/fccba8cd2d084bddb5510817b58c16d4
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Genetically-encoded indicators of neuronal activity enable the labeling of a genetically defined population of neurons to optically monitor their activities. However, researchers often find difficulties in identifying relevant signals from excessive
Externí odkaz:
https://doaj.org/article/f9537e7d9a11414bbce33019f1ed6712
Autor:
Ah-Hyoung Lee, Jihun Lee, Farah Laiwalla, Vincent Leung, Jiannan Huang, Arto Nurmikko, Yoon-Kyu Song
Publikováno v:
Micromachines, Vol 11, Iss 10, p 925 (2020)
Implantable active electronic microchips are being developed as multinode in-body sensors and actuators. There is a need to develop high throughput microfabrication techniques applicable to complementary metal–oxide–semiconductor (CMOS)-based sil
Externí odkaz:
https://doaj.org/article/7814b024b37c4861ab4f2fdbd6fa627d
Publikováno v:
Sensors, Vol 13, Iss 5, Pp 6014-6031 (2013)
We have developed a prototype cortical neural sensing microsystem for brain implantable neuroengineering applications. Its key feature is that both the transmission of broadband, multichannel neural data and power required for the embedded microelect
Externí odkaz:
https://doaj.org/article/ebe79a55f75648beb9ab3097a11ad7db
Publikováno v:
Sensors, Vol 13, Iss 6, Pp 6900-6909 (2013)
In this study, we explored magnetic nanoparticles translocating through a nanopore in the presence of an inhomogeneous magnetic field. By detecting the ionic current blockade signals with a silicon nitride nanopore, we found that the translocation ve
Externí odkaz:
https://doaj.org/article/f04684ea6164430480183097a61077ee
Autor:
Dayoung Lee, Seungki Baek, Young-Youb Kim, Yongbin Bang, Han Na Jung, Hyung-Jun Im, Yoon-Kyu Song
Publikováno v:
ACS Applied Materials & Interfaces. 14:37493-37503
We developed hybrid nanospheres comprised of two of the most important biomolecules in nature, DNA and proteins, which have excellent biocompatibility, high drug payload capacity
Publikováno v:
Chinese Chemical Letters. 31:1137-1140
Here, we use two important biomaterials, protein and DNA, to construct self-assembled linear nanostructures through Watson-Crick base-paring of DNAs. We apply a simple magnetic separation method to purify traptavidin-DNA conjugates, and demonstrate s