Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Yoon Soo Pyon"'
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52881 (2012)
Structural variation (SV) has been reported to be associated with numerous diseases such as cancer. With the advent of next generation sequencing (NGS) technologies, various types of SV can be potentially identified. We propose a model based clusteri
Externí odkaz:
https://doaj.org/article/da67b9147682448b87ce4b10cefedec3
Autor:
Daniel E. Geraghty, Chul Woo Pyo, Ruihan Wang, Yoon Soo Pyon, Akiko Ishitani, Anajane G. Smith, Shalini E. Pereira, Wyatt C. Nelson, Carly Hennessey, David Vogan
Publikováno v:
Human Immunology. 76(12):928-938
Clinical immunogenetics laboratories performing routine sequencing of human leukocyte antigen (HLA) genes in support of hematopoietic cell transplantation are motivated to upgrade to next-generation sequencing (NGS) technology by its potential for co
Publikováno v:
PLoS ONE. Dec2012, Vol. 7 Issue 12, p1-13. 13p.
Publikováno v:
Bioinformatics (Oxford, England). 29(1)
Motivation: For many complex traits/diseases, it is believed that rare variants account for some of the missing heritability that cannot be explained by common variants. Sequencing a large number of samples through DNA pooling is a cost-effective str
Publikováno v:
International journal of data mining and bioinformatics. 5(3)
A comprehensive understanding of cancer progression may shed light on genetic and molecular mechanisms of oncogenesis, and provide important information for effective diagnosis and prognosis. We propose a multicategory logit model to identify genes t
Publikováno v:
ICCABS
Structural variation (SV) has been reported to be associated with numerous diseases such as cancer. With the advent of next generation sequencing (NGS) technologies, various types of SV can be potentially identified. We propose a model based clusteri
Autor:
Jing Li, Yoon Soo Pyon
Publikováno v:
BIBM
A comprehensive understanding of cancer progression may shed light on genetic and molecular mechanisms of oncogenesis, and it may provide much needed information for effective diagnosis, prognosis, and optimal therapy. However, despite considerable e
Autor:
Xinxia Peng, Chul-Woo Pyo, Matthew Thomas, Yoon Soo Pyon, Lynn Law, Ruihan Wang, Daniel Geraghty, Michael Katze
Publikováno v:
The Journal of Immunology. 194:113.3-113.3
The relevance of MHC genes to HIV infection and disease progression is well established, and nonhuman primates are the most important model for AIDS vaccine research and development. However, due to the structural and sequence complexity of the macaq
Autor:
Lawrence Hon, Kevin Eng, Swati Ranade, Cynthia Vierra-Green, Richard Hall, Yoon Soo Pyon, Daniel E. Geraghty, Chul-Woo Pyo
Publikováno v:
Human Immunology. 75:5
Aim The knowledge of complete haplotype structure and underlying genetic variation is often key in understanding gene function, phenotype, and medically relevant traits such as susceptibility to disease and individual response to drugs. However, geno
Autor:
Chul-Woo Pyo, Daniel E. Geraghty, Ruihan Wang, Shu Shen, Akiko Ishitani, Yoon Soo Pyon, Shalini E. Pereira, Wyatt C. Nelson, Anajane G. Smith
Publikováno v:
Human Immunology. 75:479
Aim Current technologies for analysis of complex polymorphic gene systems restrict the ability to routinely obtain both breadth (number of loci) and depth (allele resolution) of data. The costs of increasing the breadth of analysis are additive in th