Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Yoon Seok Roh"'
Autor:
Hwan Ma, Guo-Yan Sui, Jeong-Su Park, Feng Wang, Yuanqiang Ma, Dong-Su Shin, Nodir Rustamov, Jun Sung Jang, Soo Im Chang, Jin Lee, Yoon Seok Roh
Publikováno v:
Heliyon, Vol 10, Iss 20, Pp e39534- (2024)
11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) is a key enzyme involved in the conversion of cortisone to active cortisol in the liver. Elevated cortisol levels can trigger oxidative stress, inflammation, and hepatocyte damage, highlighting the
Externí odkaz:
https://doaj.org/article/b9edd4e25fe4413592c606dbb3698a3d
Autor:
Chuck Chang, Yoon Seok Roh, Min Du, Yun Chai Kuo, Yiming Zhang, Mary Hardy, Roland Gahler, Julia Solnier
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 5625 (2024)
We investigated the pharmacokinetic pathway of berberine and its metabolites in vitro, in Caco-2 cells, and in human participants following the administration of dihydroberberine (DHB) and micellar berberine (LipoMicel®, LMB) formulations. A pilot t
Externí odkaz:
https://doaj.org/article/3480bf7a7a514f848d8a1d84740a65c5
Autor:
Julia Solnier, Chuck Chang, Yiming Zhang, Yun Chai Kuo, Min Du, Yoon Seok Roh, Janet See, Jennifer Brix, Roland J. Gahler, Tim Green, Simon Wood
Publikováno v:
Nutrients, Vol 16, Iss 11, p 1573 (2024)
The aim of this pilot study was to evaluate and compare bioavailability and safety of two Vitamin D3 formulations (softgels) in healthy adults, at single daily doses of 1000 and 2500 IU, over a 60-day period. A total of 69 participants were initially
Externí odkaz:
https://doaj.org/article/72096bc76fd34abf9e8396505fd0b574
Autor:
Afoke Ibi, Chuck Chang, Yun Chai Kuo, Yiming Zhang, Min Du, Yoon Seok Roh, Roland Gahler, Mary Hardy, Julia Solnier
Publikováno v:
Metabolites, Vol 14, Iss 5, p 265 (2024)
This study evaluated the differences in the metabolite profile of three n-3 FA fish oil formulations in 12 healthy participants: (1) standard softgels (STD) providing 600 mg n-3 FA; (2) enteric-coated softgels (ENT) providing 600 mg n-3 FA; (3) a new
Externí odkaz:
https://doaj.org/article/9fedda1df5854e5dadac1b28e3eed5f7
Autor:
Ji-Won Jung, Feng Wang, Ayman Turk, Jeong-Su Park, Hwan Ma, Yuanqiang Ma, Hye-Rin Noh, Guoyan Sui, Dong-Su Shin, Mi-Kyeong Lee, Yoon Seok Roh
Publikováno v:
Molecules, Vol 28, Iss 22, p 7484 (2023)
Zaluzanin C (ZC), a sesquiterpene lactone isolated from Laurus nobilis L., has been reported to have anti-inflammatory and antioxidant effects. However, the mechanistic role of ZC in its protective effects in Kupffer cells and hepatocytes has not bee
Externí odkaz:
https://doaj.org/article/e6ad9ad53c0d4d989228e354377233c1
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 14890 (2022)
Mitochondria play a central role in the pathophysiology of inflammatory bowel disease (IBD) and colorectal cancer (CRC). The maintenance of mitochondrial function is necessary for a stable immune system. Mitochondrial dysfunction in the gastrointesti
Externí odkaz:
https://doaj.org/article/463987cbf90344a5829b59d7a36bbc2b
Autor:
Dong Hun Lee, Young Suk Jung, Jaesuk Yun, Sang Bae Han, Yoon Seok Roh, Min Jong Song, Jin Tae Hong
Publikováno v:
Redox Biology, Vol 32, Iss , Pp - (2020)
Acetaminophen (APAP) is one of the most frequently used drugs; however, its overdose leads to acute liver injury. Recently, studies have reported that the adduction of peroxiredoxin 6 (PRDX6), a member of the PRDX family of antioxidant enzymes, is as
Externí odkaz:
https://doaj.org/article/8a03f8c0b6d440d1865ed11ed2fd5c8b
Autor:
Ling Yang, Kouichi Miura, Bi Zhang, Hiroshi Matsushita, Yoon Mee Yang, Shuang Liang, Jingyi Song, Yoon Seok Roh, Ekihiro Seki
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 3, Iss 3, Pp 469-483 (2017)
Background & Aims: Toll-like receptor 4 (TLR4) signaling is activated through 2 adaptor proteins: MyD88 and TIR-domain containing adaptor-inducing interferon-β (TRIF). TLR4 and MyD88 are crucial in nonalcoholic steatohepatitis (NASH) and fibrosi
Externí odkaz:
https://doaj.org/article/dc7862fa85a64987a796495619396de9
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114071 (2014)
Inflammatory response and cell death in hepatocytes are hallmarks of chronic liver disease, and, therefore, can be effective therapeutic targets. Neurotropin® (NTP) is a drug widely used in Japan and China to treat chronic pain. Although NTP has bee
Externí odkaz:
https://doaj.org/article/37ebb39755364299a09b7853004f8bb8
Autor:
Nodir Rustamov, Yuanqiang Ma, Jeong-Su Park, Feng Wang, Hwan Ma, Guoyan Sui, Gahye Moon, Hwan-Soo Yoo, Yoon-Seok Roh
Publikováno v:
Foods; Jul2024, Vol. 13 Issue 13, p1-13, 13p, 4 Graphs