Zobrazeno 1 - 10
of 168
pro vyhledávání: '"Yoon Ki Kim"'
Autor:
Hyun Jung Hwang, Yoon Ki Kim
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 6, Pp 1272-1280 (2024)
Abstract Circular RNAs (circRNAs) are covalently closed single-stranded RNAs without a 5′ cap structure and a 3′ poly(A) tail typically present in linear mRNAs of eukaryotic cells. CircRNAs are predominantly generated through a back-splicing proc
Externí odkaz:
https://doaj.org/article/7c8f3b1e8ea14cb79db74bdde7655c07
Autor:
Sang Won An, Seong Bin Bae, Beomjun Kim, Yoon Ki Kim, Jaeseung Kim, Tae Hyun Jung, Jae Heon Lee, Sang Woo Lee, Yu Bin Park, Hyunjung Kim, Hyobin Yoo, Sang Mo Yang
Publikováno v:
Advanced Materials Interfaces, Vol 11, Iss 21, Pp n/a-n/a (2024)
Abstract Recently, HfO2‐based ferroelectric thin films have attracted widespread interest in developing next‐generation nonvolatile memories. To form a metastable ferroelectric orthorhombic phase in HfO2, a post‐annealing process is typically n
Externí odkaz:
https://doaj.org/article/3f71b7f4aa1840dd8cc8e70536e6308f
Autor:
Hyun Jung Hwang, Tae Lim Park, Hyeong-In Kim, Yeonkyoung Park, Geunhee Kim, Chiyeol Song, Won-Ki Cho, Yoon Ki Kim
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract YTHDF2 has been extensively studied and typified as an RNA-binding protein that specifically recognizes and destabilizes RNAs harboring N 6-methyladenosine (m6A), the most prevalent internal modification found in eukaryotic RNAs. In this stu
Externí odkaz:
https://doaj.org/article/96ca7caf37e046bea866310174913c37
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 2, Pp 283-289 (2023)
Protein synthesis: Seeing single mRNA molecules Single-molecule fluorescence imaging is revealing the formation of circular mRNA and the complex interplay of messenger RNA (mRNA) and ribosomal proteins during translation, the decoding of mRNA to form
Externí odkaz:
https://doaj.org/article/575036d670114184ae962f5b6ab08e05
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
LC3/ATG8 plays an essential role in autophagy. Here the authors show that LC3B exhibits RNA-binding ability and induces rapid degradation of target mRNAs via autophagic activation, highlighting the interplay between autophagy and RNA biology.
Externí odkaz:
https://doaj.org/article/448a93af12824e0db9efe28eb4a68552
Autor:
Jun-Ha Hwang, Kyung Min Kim, Ho Taek Oh, Gi Don Yoo, Mi Gyeong Jeong, Hyun Lee, Joori Park, Kwon Jeong, Yoon Ki Kim, Young-Gyu Ko, Eun Sook Hwang, Jeong-Ho Hong
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Mitochondrial biogenesis is stimulated to meet energy requirements in response to extracellular signals including exercise. TAZ is revealed as a novel stimulator for mitochondrial biogenesis and facilitates exercise-induced muscle adaptation.
Externí odkaz:
https://doaj.org/article/f541433f82f445a78db350d233d60d3d
Autor:
Doyeon Kim, Sukjun Kim, Joori Park, Hee Ryung Chang, Jeeyoon Chang, Junhak Ahn, Heedo Park, Junehee Park, Narae Son, Gihyeon Kang, Jeonghun Kim, Kisoon Kim, Man-Seong Park, Yoon Ki Kim, Daehyun Baek
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Here, Kim et al. apply various sequencing techniques (RPF-seq, QTI-seq, mRNA-seq, sRNA-seq) to unravel the high-resolution, longitudinal translatome and transcriptome of SARS-CoV-2. They identify a translation initiation site in the leader sequence o
Externí odkaz:
https://doaj.org/article/88663867222744148a822f50ee1d92bf
Autor:
Sukjun Kim, Soyoung Kim, Hee Ryung Chang, Doyeon Kim, Junehee Park, Narae Son, Joori Park, Minhyuk Yoon, Gwangung Chae, Young-Kook Kim, V. Narry Kim, Yoon Ki Kim, Jin-Wu Nam, Chanseok Shin, Daehyun Baek
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
miRNAs are loaded into Argonaute protein and repress complementary mRNA targets. Here the authors show the unappreciated role of RNA binding proteins for efficient miRNA targeting and expand the current understanding of miRNA targeting.
Externí odkaz:
https://doaj.org/article/fa80ba4bd3e24c5eae00608527853f85
UXT chaperone prevents proteotoxicity by acting as an autophagy adaptor for p62-dependent aggrephagy
Autor:
Min Ji Yoon, Boyoon Choi, Eun Jin Kim, Jiyeon Ohk, Chansik Yang, Yeon-Gil Choi, Jinyoung Lee, Chanhee Kang, Hyun Kyu Song, Yoon Ki Kim, Jae-Sung Woo, Yongcheol Cho, Eui-Ju Choi, Hosung Jung, Chungho Kim
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
p62/SQSTM1 acts as a key mediator in the selective autophagy of protein aggregates, or aggrephagy. Here the authors identify the prefoldin-like chaperone UXT as an autophagy adaptor of p62 dependent aggrephagy and show that ectopic UXT expression del
Externí odkaz:
https://doaj.org/article/f97d34af557c40b1a93c7c19606cff1c
Autor:
Chunmei Jin, Yeunkum Lee, Hyojin Kang, Kwon Jeong, Joori Park, Yinhua Zhang, Hyae Rim Kang, Ruiying Ma, Hyunyoung Seong, Yoonhee Kim, Hosung Jung, Jin Young Kim, Yoon Ki Kim, Kihoon Han
Publikováno v:
Molecular Brain, Vol 14, Iss 1, Pp 1-5 (2021)
Abstract The SH3 and multiple ankyrin repeat domains 3 (Shank3) protein is a core organizer of the macromolecular complex in excitatory postsynapses, and its defects cause numerous synaptopathies, including autism spectrum disorders. Although the fun
Externí odkaz:
https://doaj.org/article/a5d01e752d3f48ab8b849fd86580ad31