Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Yoon Jong Choi"'
Autor:
Victoria Brown, Nealia House, Phil Ramsden, Karen Ho, Hsin-Jung Wu, Erik Wilker, Jian Guo, Maxine Chen, Douglas Wilson, Neil Bifulco, Steve Wenglowsky, Yoon Jong Choi, Kerrie Faia
Publikováno v:
Cancer Research. 83:P6-10
Cyclin-dependent kinase 4/6 (CDK4/6) inhibitors are standard of care in combination with endocrine therapy in advanced hormone receptor-positive (HR+), human epidermal growth factor receptor 2 negative (HER2-) breast cancer. Despite improved progress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc6d20bceceb1cc735d1a8f803dbcaf5
https://doi.org/10.1158/1538-7445.sabcs22-p6-10-07
https://doi.org/10.1158/1538-7445.sabcs22-p6-10-07
Autor:
Brown, Victoria E., Moore, Sydney L., Chen, Maxine, House, Nealia, Ramsden, Philip, Hsin-Jung Wu, Ribich, Scott, Grassian, Alexandra R., Yoon Jong Choi
Publikováno v:
NAR Cancer; Sep2023, Vol. 5 Issue 3, p1-16, 16p
Autor:
Nan Ke, Yoon Jong Choi, David A. Orlando, Emmanuelle di Tomaso, Kevin Sprott, Christian Fritz, Shanhu Hu, Michael J. Bradley, John Carulli, Darby Schmidt, Eric R. Olson, Stephane Ciblat, Nisha Rajagopal, Jason J. Marineau, J. Graeme Hodgson, Dana K. Winter, Anzhelika Kabro, Yixuan Ren, Kristin B. Hamman, Sydney Alnemy, Liv Johannessen
Publikováno v:
Cancer Research. 79:3479-3491
Recent studies suggest that targeting transcriptional machinery can lead to potent and selective anticancer effects in cancers dependent on high and constant expression of certain transcription factors for growth and survival. Cyclin-dependent kinase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06450210654bdc8576936764e0d54305
https://doi.org/10.1158/0008-5472.can-19-0119
https://doi.org/10.1158/0008-5472.can-19-0119
Autor:
Victoria Brown, Phil Ramsden, Nealia House, Richard Vargas, Jian Guo, Ruduan Wang, Riadh Lobbardi, Maxine Chen, Douglas Wilson, Joseph Kim, Neil Bifulco, Michelle Maynard, Emanuele Perola, Dean Zhang, Steve Wenglowsky, Yoon Jong Choi
Publikováno v:
Cancer Research. 82:2306-2306
Background: Cyclin-dependent kinases (CDK) are a class of enzymes that, along with their regulatory cyclin binding partners, drive cell cycle progression. Cell cycle dysregulation is a hallmark of cancer and targeting its genetic drivers can confer t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d89d4c271e2dff423ca97010d6af0af
https://doi.org/10.1158/1538-7445.am2022-2306
https://doi.org/10.1158/1538-7445.am2022-2306
Publikováno v:
Journal of Loss Prevention in the Process Industries. 72:104499
Azo compounds are self-reactive chemicals that violently produce flammable gases with heat release (i.e., an exothermic reaction). However, the explosion mechanism and ignition probability of azo compounds have not been clearly defined for storage or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08c09af469d94c1df6ef76c6ca3fad46
https://doi.org/10.1016/j.jlp.2021.104499
https://doi.org/10.1016/j.jlp.2021.104499
Autor:
Borja Saez, David T. Scadden, Nickolas A. Bacon, Lars Anders, Sabina Signoretti, Richard A. Young, Per Hydbring, Yoon Jong Choi, Ilona Kalaszczynska, Colleen Cook, Joanna Stefano, Piotr Sicinski
Publikováno v:
PMC
SummaryD-type cyclins (D1, D2, and D3) are components of the mammalian core cell-cycle machinery and function to drive cell proliferation. Here, we report that D-cyclins perform a rate-limiting antiapoptotic function in vivo. We found that acute shut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf12c569d17ec093624aa3972795508b
Autor:
Pere Puigserver, Joao Paulo Camporez, Xiaoyong Yang, Michael J. Jurczak, Ji Hong Lim, Yoonjin Lee, Helen Chim, Francisca Vazquez, Gerald I. Shulman, Piotr Sicinski, Nicola Tolliday, John E. Dominy, Hai Bin Ruan, Yoon Jong Choi
Publikováno v:
Nature
Insulin constitutes a principal evolutionarily conserved hormonal axis for maintaining glucose homeostasis; dysregulation of this axis causes diabetes. PGC-1α (peroxisome-proliferator-activated receptor-γ coactivator-1α) links insulin signalling t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd225c3ea41d9f47a9d77b5e7efba988
https://doi.org/10.1038/nature13267
https://doi.org/10.1038/nature13267
Publikováno v:
International Journal of Precision Engineering and Manufacturing. 15:433-438
Crack resistance is important to exam the structures destroyed under static and dynamic load as well as to the ceramic products under extreme mechanical and thermal load. But in addition to the metallic material, ceramic and ceramic composite materia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db08a55ea40f400b60cd99eb69e326f0
https://doi.org/10.1007/s12541-014-0354-5
https://doi.org/10.1007/s12541-014-0354-5
Autor:
Ruiyang Tian, Penelope Miron, Gautam Maulik, Scott J. Rodig, Bose Kochupurakkal, Alexander Miron, Debajit K. Biswas, Shannon T. Bailey, Teresa V. Bowman, Kathleen M. Foley, Yoon Jong Choi, J. Dirk Iglehart, Myles Brown
Publikováno v:
Molecular Cancer Research. 12:408-420
Breast cancers with HER2 overexpression are sensitive to drugs targeting the receptor or its kinase activity. HER2-targeting drugs are initially effective against HER2-positive breast cancer, but resistance inevitably occurs. We previously found that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::692427f87b44f0c9cf18504ceca7a1eb
https://doi.org/10.1158/1541-7786.mcr-13-0206-t
https://doi.org/10.1158/1541-7786.mcr-13-0206-t
Autor:
Andrew L. Kung, Harald von Boehmer, Per Hydbring, Takaomi Sanda, Joanna Stefano, Sabina Signoretti, Xiaoyu Li, Amanda L. Christie, A. Thomas Look, Yoon Jong Choi, Piotr Sicinski
Publikováno v:
Cancer Cell. 22(4):438-451
SummaryD-cyclins represent components of cell cycle machinery. To test the efficacy of targeting D-cyclins in cancer treatment, we engineered mouse strains that allow acute and global ablation of individual D-cyclins in a living animal. Ubiquitous sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8edd44889d950ef9c24013849b484988