Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Yoon Ji Lim"'
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Inactivation of the genes involved in histone H3-lysine 4 methylation abates the biosynthesis of pigment azaphilone in Monascus purpureus
Autor: Jae-Won Suh, Bijinu Balakrishnan, Hyung-Jin Kwon, Yoon Ji Lim
Publikováno v: Journal of Applied Biological Chemistry. 62:157-165
Di- and tri-methylation of lysine 4 on histone H3 (H3K4me2 and H3K4me3, respectively) are epigenetic markers of active genes. Complex associated with Set1 (COMPASS) mediates these H3K4 methylations. The involvement of COMPASS activity in secondary me
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::537c37d9eda8695e1424ac4e64e8adbe
https://doi.org/10.3839/jabc.2019.022
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5
Extractive fermentation of Monascus purpureus promotes the production of oxidized congeners of the pigment azaphilone
Autor: Si-Hyung Park, Yoon Ji Lim, Hyung-Jin Kwon, Doh Won Lee
Publikováno v: Journal of Applied Biological Chemistry. 61:327-334
Monascus is a source of food colorant with high productivity of the pigment azaphilone. Monascus azaphilone (MAz) is biosynthesized through a single non-reducing polyketide pathway, the major components of which are ankaflavin (1), monascin (2), rubr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fd9dd51ae89c4d01d476a120b49f5263
https://doi.org/10.3839/jabc.2018.046
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6
Production of a hypothetical polyene substance by activating a cryptic fungal PKS-NRPS hybrid gene in Monascus purpureus
Autor: Hyung-Jin Kwon, Yoon Ji Lim, Si-Hyung Park, Lee DohWon, Jeong Ju Choi, Balakrishnan Bijinu
Publikováno v: Journal of Applied Biological Chemistry. 61:83-91
Advances in bacterial and fungal genome mining uncover a plethora of cryptic secondary metabolite biosynthetic gene clusters. Guided by the genome information, targeted transcriptional derepression could be employed to determine the product of a cryp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6cad00bd5e680977bd8350b49de05967
https://doi.org/10.3839/jabc.2018.013
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7
Selective production of red azaphilone pigments in a Monascus purpureus mppDEG deletion mutant
Autor: Doh Won Lee, Hyung-Jin Kwon, Yoon Ji Lim, Si-Hyung Park, Seok Hyun Hwang, Bijinu Balakrishnan
Publikováno v: Journal of Applied Biological Chemistry. 60:249-256
The Monascus azaphilone (MAz) pigment is a wellknown food colorant that has yellow, orange and red components. The structures of the yellow and orange MAz differ by two hydride reductions, with yellow MAz being the reduced form. Orange MAz can be non
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bb767786155789b570be0b22b9cb5364
https://doi.org/10.3839/jabc.2017.040
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9
Genetic localization of the orevactaene/epipyrone biosynthetic gene cluster in Epicoccum nigrum
Autor: Hyung-Jin Kwon, Si-Hyung Park, Yoon Ji Lim, Eun Ha Choi
Publikováno v: Bioorganic & Medicinal Chemistry Letters. 30:127242
Epipyrone (EPN)-A (syn. orevactaene) is a polyketide compound of 3-d-galactosyl-4-hydroxy-2-pyrone with a modified heptaene acyl moiety, produced from Epicoccum nigrum and was reported to have various biological activities. Genome analysis identified
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::417f6b13847541b010a4f3986e9087b7
https://doi.org/10.1016/j.bmcl.2020.127242
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