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Autor:
Tomohiro Hasegawa, Takemasa Takii, Kenji Ogawa, Ryuji Kuroishi, Kikuo Onozaki, Laurent Kremer, Yasuhiro Horita, Taku Chiba, Yasuo Sato, YooSa Lee
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 21:899-903
The present study was undertaken to optimize the anti-tubercular activity of 2-acetamido-2-deoxy-β-D-glucopyranosyl N,N-dimethyldithiocarbamate (OCT313, Glc-NAc-DMDC), a lead compound previously reported by us. Structural modifications of OCT313 inc