Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Yoo-Jin Bang"'
A lipid nanoparticle platform incorporating trehalose glycolipid for exceptional mRNA vaccine safety
Autor:
Seo-Hyeon Bae, Soyeon Yoo, Jisun Lee, Hyo-Jung Park, Sung Pil Kwon, Harin Jin, Sang-In Park, Yu-Sun Lee, Yoo-Jin Bang, Gahyun Roh, Seonghyun Lee, Sue Bean Youn, In Woo Kim, Ho Rim Oh, Ashraf K. El-Damasy, Gyochang Keum, Hojun Kim, Hyewon Youn, Jae-Hwan Nam, Eun-Kyoung Bang
Publikováno v:
Bioactive Materials, Vol 38, Iss , Pp 486-498 (2024)
The rapid development of messenger RNA (mRNA) vaccines formulated with lipid nanoparticles (LNPs) has contributed to control of the COVID-19 pandemic. However, mRNA vaccines have raised concerns about their potential toxicity and clinical safety, inc
Externí odkaz:
https://doaj.org/article/c48d472deaca44c3aad77211ea466fb1
Autor:
Jae-Yong Kim, Kyeongseok Jeon, Sang-In Park, Yoo-Jin Bang, Hyeong-Jun Park, Hye Won Kwak, Do-Hyung Kim, Soo-Yeon Lee, Eun-Jin Choi, Nam-Hyuk Cho, Jae-Hwan Nam
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-5 (2023)
Abstract We developed a promising mRNA vaccine against severe fever with thrombocytopenia syndrome (SFTS), an infectious disease caused by the SFTS virus that is primarily transmitted through tick bites. Administration of lipid nanoparticle-encapsula
Externí odkaz:
https://doaj.org/article/c37fde598cb0477e989fdf8553c809f4
Autor:
Hyeong-Jun Park, Yoo-Jin Bang, Sung Pil Kwon, Woori Kwak, Sang-In Park, Gahyun Roh, Seo-Hyeon Bae, Jae-Yong Kim, Hye Won Kwak, Yongkwan Kim, Soyeon Yoo, Daegeun Kim, Gyochang Keum, Eun-Kyoung Bang, So-Hee Hong, Jae-Hwan Nam
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-13 (2023)
Abstract In response to the COVID-19 pandemic, different types of vaccines, such as inactive, live-attenuated, messenger RNA (mRNA), and protein subunit, have been developed against SARS-CoV-2. This has unintentionally created a unique scenario where
Externí odkaz:
https://doaj.org/article/5c5ff5fcc5a54c4e820b09bd1e7031cd
Autor:
Jae-Yong Kim, Kyeongseok Jeon, Jung Joo Hong, Sang-In Park, Hyeonggon Cho, Hyo-Jung Park, Hye Won Kwak, Hyeong-Jun Park, Yoo-Jin Bang, Yu-Sun Lee, Seo-Hyeon Bae, So-Hee Kim, Kyung-Ah Hwang, Dae-Im Jung, Seong Hoo Cho, Sang Hwan Seo, Green Kim, Hanseul Oh, Hwal-Yong Lee, Ki Hyun Kim, Hee-Young Lim, Pyeonghwa Jeon, Joo-Yeon Lee, Junho Chung, Sang-Myeong Lee, Hae Li Ko, Manki Song, Nam-Hyuk Cho, Young-suk Lee, So-Hee Hong, Jae-Hwan Nam
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Severe fever with thrombocytopenia syndrome virus was first discovered in 2009 as the causative agent of severe fever with thrombocytopenia syndrome. Despite its potential threat to public health, no prophylactic vaccine is yet available. Th
Externí odkaz:
https://doaj.org/article/595caf71034941448061581088917336
Autor:
Hye Won Kwak, So-Hee Hong, Hyo-Jung Park, Hyeong-Jun Park, Yoo-Jin Bang, Jae-Yong Kim, Yu-Sun Lee, Seo-Hyeon Bae, Hyunho Yoon, Jae-Hwan Nam
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-12 (2022)
Abstract Background Adjuvant therapies such as radiation therapy, chemotherapy, and immunotherapy are usually given after cancer surgery to improve the survival of cancer patients. However, despite advances in several adjuvant therapies, they are sti
Externí odkaz:
https://doaj.org/article/c4a9343c007342698eacacd0233adb5f
Autor:
Yoo-Jin Bang, So-Hee Hong, Hyo-Jung Park, Hye Won Kwak, Yu-Sun Lee, Jae-Yong Kim, Hyeong-Jun Park, Seo-Hyeon Bae, Hye-Jung Kim, Yun-Hee Kim, Hae Li Ko, Sang-In Park, Hun Kim, Gyeongjoo Park, Man-Seong Park, Jun Chang, Jae-Hwan Nam
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract There is an unmet need for new influenza vaccine strategies that compensate for impaired vaccine responses in elderly individuals. Here, we evaluated the effectiveness of a single-stranded RNA (ssRNA) as an adjuvant to enhance the efficacy o
Externí odkaz:
https://doaj.org/article/a5a57738d3804b2ea87a1b31eecaa317
Autor:
Hye-Jung Kim, Hye Won Kwak, Kyung Won Kang, Yoo-Jin Bang, Yu-Sun Lee, Hyeong-Jun Park, Jae-Yong Kim, Hyo-Jung Park, Kyung-Ah Hwang, Sang-Myeong Lee, Jae-Hwan Nam
Publikováno v:
Pharmaceutics, Vol 12, Iss 5, p 441 (2020)
The effectiveness of vaccines is enhanced by adding adjuvants. Furthermore, the selection of an inoculation route depends on the type of adjuvant used and is important for achieving optimum vaccine efficacy. We investigated the immunological differen
Externí odkaz:
https://doaj.org/article/4886507f6ad3401e97a1779b28db1ee0
Autor:
Jae-Yong Kim, Kyeongseok Jeon, Jung Joo Hong, Sang-In Park, Hyeong-Gon Cho, Hyo-Jung Park, Hye Won Kwak, Hyeong-Jun Park, Yoo-Jin Bang, Yu-Sun Lee, Seo-Hyeon Bae, So-Hee Kim, Kyung-Ah Hwang, Dae-Im Jung, Seong Hoo Cho, Sang Hwan Seo, Green Kim, Hanseul Oh, Hwal-Yong Lee, Ki Hyun Kim, Hee-Young Lim, Pyeonghwa Jeon, Joo-Yeon Lee, Junho Chung, Sang-Myeong Lee, Hae Li Ko, Manki Song, Nam-Hyuk Cho, Young-suk Lee, So-Hee Hong, Jae-Hwan Nam
Severe Fever with Thrombocytopenia Syndrome Virus(SFTSV) was first discovered in 2009 as the causative agent of severe fever with thrombocytopenia syndrome. Despite its potential threat to public health, no prophylactic vaccine is yet available. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::289f6cd8b1611749fab4a32ead689c7b
https://doi.org/10.21203/rs.3.rs-2420776/v1
https://doi.org/10.21203/rs.3.rs-2420776/v1
Autor:
Jae-Hwan Nam, Hyeong-Jun Park, Yoo-Jin Bang, Sung Pil Kwon, Woori Kwak, Sang-In Park, Gahyun Roh, Seo-Hyeon Bae, Jae-Yong Kim, Hye Won Kwak, Yongkwan Kim, Soyeon Yoo, Daegeun Kim, Gyochang Keum, Eun-Kyoung Bang, So-Hee Hong
In response to the COVID-19 pandemic, different types of vaccines, such as inactive, live-attenuated, messenger RNA, and protein subunit, have been developed against SARS-CoV2. This circumstance has unintentionally led to heterologous prime-boost vac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2da637169e1fd2649efc753bf9cfed8c
https://doi.org/10.21203/rs.3.rs-2361251/v1
https://doi.org/10.21203/rs.3.rs-2361251/v1
Autor:
Hye Won Kwak, Wooseok Shin, Kyunghwa Baik, Minsun Kim, YongWook Park, So‐Hee Hong, Hyo‐Jung Park, Hyeong‐Jun Park, Yoo‐Jin Bang, Jae‐Yong Kim, Yu‐Sun Lee, In‐Beom Kim, Hong‐Lim Kim, Hun Kim, Jae‐Hwan Nam
Publikováno v:
Microbiology and immunologyREFERENCES. 66(11)
Following the development of various types of vaccines, the use of adjuvants to boost vaccine efficacy has become a focus of research. Aluminum hydroxide (alum), the most commonly used adjuvant, induces a certain immune response and ensures safety in