Zobrazeno 1 - 10
of 167
pro vyhledávání: '"Yonova, P. A."'
Autor:
Lingyan Chen, James E. Peters, Bram Prins, Elodie Persyn, Matthew Traylor, Praveen Surendran, Savita Karthikeyan, Ekaterina Yonova-Doing, Emanuele Di Angelantonio, David J. Roberts, Nicholas A. Watkins, Willem H. Ouwehand, John Danesh, Cathryn M. Lewis, Paola G. Bronson, Hugh S. Markus, Stephen Burgess, Adam S. Butterworth, Joanna M. M. Howson
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Mendelian randomization can be used to mimic the effects of protein-targeting drugs in a population of individuals. Here, the authors have identified potential causal proteins for stroke in a two-sample Mendelian randomization framework, providing po
Externí odkaz:
https://doaj.org/article/36ad3820dd294fba8ce25e16910ffecf
Autor:
Anna Veprik, Geoffrey Denwood, Dong Liu, Rula Bany Bakar, Valentin Morfin, Kara McHugh, Nchimunya N. Tebeka, Laurène Vetterli, Ekaterina Yonova-Doing, Fiona Gribble, Frank Reimann, Kyle L. Hoehn, Piers A. Hemsley, Jonas Ahnfelt-Rønne, Patrik Rorsman, Quan Zhang, Heidi de Wet, James Cantley
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
Veprik et al. show that Acetyl-CoA-carboxylase 1 (ACC1), an enzyme that couples glucose metabolism to lipogenesis, is involved in glucagon secretion and regulates S-acylation of critical glucose-sensing proteins. Loss of ACC1 in pancreatic alpha-cell
Externí odkaz:
https://doaj.org/article/166afa66325d42c88ebcf56718483f72
Autor:
Mekha Mathew, Jeremy van Vlymen, Bernardo Meza-Torres, William Hinton, Gayathri Delanerolle, Ivelina Yonova, Michael Feher, Xuejuan Fan, Harshana Liyanage, Mark Joy, Fabrizio Carinci, Simon de Lusignan
Publikováno v:
JMIR Research Protocols, Vol 11, Iss 4, p e35971 (2022)
BackgroundSocial distancing and other nonpharmaceutical interventions to reduce the spread of COVID-19 infection in the United Kingdom have led to substantial changes in delivering ongoing care for patients with chronic conditions, including type 2 d
Externí odkaz:
https://doaj.org/article/885d84b8fd904f2287b2bd69c3314cca
Publikováno v:
EPTCS 160, 2014, pp. 16-29
We study whether, in the pi-calculus, the match prefix-a conditional operator testing two names for (syntactic) equality-is expressible via the other operators. Previously, Carbone and Maffeis proved that matching is not expressible this way under ra
Externí odkaz:
http://arxiv.org/abs/1408.1454
We study whether, in the pi-calculus, the match prefix---a conditional operator testing two names for (syntactic) equality---is expressible via the other operators. Previously, Carbone and Maffeis proved that matching is not expressible this way unde
Externí odkaz:
http://arxiv.org/abs/1407.6406
Autor:
Ekaterina Yonova-Doing, Wanting Zhao, Robert P. Igo, Chaolong Wang, Periasamy Sundaresan, Kristine E. Lee, Gyungah R. Jun, Alexessander Couto Alves, Xiaoran Chai, Anita S. Y. Chan, Mei Chin Lee, Allan Fong, Ava G. Tan, Chiea Chuen Khor, Emily Y. Chew, Pirro G. Hysi, Qiao Fan, Jacqueline Chua, Jaeyoon Chung, Jiemin Liao, Johanna M. Colijn, Kathryn P. Burdon, Lars G. Fritsche, Maria K. Swift, Maryam H. Hilmy, Miao Ling Chee, Milly Tedja, Pieter W. M. Bonnemaijer, Preeti Gupta, Queenie S. Tan, Zheng Li, Eranga N. Vithana, Ravilla D. Ravindran, Soon-Phaik Chee, Yuan Shi, Wenting Liu, Xinyi Su, Xueling Sim, Yang Shen, Ya Xing Wang, Hengtong Li, Yih-Chung Tham, Yik Ying Teo, Tin Aung, Kerrin S. Small, Paul Mitchell, Jost B. Jonas, Tien Yin Wong, Astrid E. Fletcher, Caroline C. W. Klaver, Barbara E. K. Klein, Jie Jin Wang, Sudha K. Iyengar, Christopher J. Hammond, Ching-Yu Cheng
Publikováno v:
Communications Biology, Vol 3, Iss 1, Pp 1-8 (2020)
Here, the authors report a multi-ethnic genome wide association meta-analysis of 12 studies from the International Cataract Genetics Consortium. They find six new loci associated with age-related nuclear cataract, in addition to replicating the assoc
Externí odkaz:
https://doaj.org/article/59d197cca67a4e4b95995e668e03898d
Autor:
Simon de Lusignan, Julian Sherlock, Oluwafunmi Akinyemi, Richard Pebody, Alex Elliot, Rachel Byford, Ivelina Yonova, Maria Zambon, Mark Joy
Publikováno v:
BMC Public Health, Vol 20, Iss 1, Pp 1-11 (2020)
Abstract Background Direct observation of the household spread of influenza and respiratory infections is limited; much of our understanding comes from mathematical models. The study aims to determine household incidence of influenza-like illness (IL
Externí odkaz:
https://doaj.org/article/0354d0670803495aac367afbf9191d10
Autor:
Simon de Lusignan, Silvia Damaso, Filipa Ferreira, Rachel Byford, Christopher McGee, Sameera Pathirannehelage, Vishvesh Shende, Ivelina Yonova, Alexander Schmidt, Anne Schuind, Gael Dos Santos
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 16, Iss 8, Pp 1762-1771 (2020)
In compliance with the European Medicine Agency guidance to detect any potential safety concerns associated with influenza vaccination, an enhanced safety surveillance study was conducted in England during the 2017/18 influenza season. The primary ob
Externí odkaz:
https://doaj.org/article/f3493645b6b64ea995dcb0dadd98b027
Autor:
Simon de Lusignan, Mansoor Ashraf, Filipa Ferreira, Manasa Tripathy, Ivelina Yonova, Imran Rafi, George Kassianos, Mark Joy
Publikováno v:
Behavioral Sciences, Vol 13, Iss 2, p 130 (2023)
Seasonal vaccination against influenza and in-pandemic COVID-19 vaccination are top public health priorities; vaccines are the primary means of reducing infections and also controlling pressures on health systems. During the 2018–2019 influenza sea
Externí odkaz:
https://doaj.org/article/54936aae6ef7430c9587b786e3e9ba0b
Autor:
Gad Abraham, Rainer Malik, Ekaterina Yonova-Doing, Agus Salim, Tingting Wang, John Danesh, Adam S. Butterworth, Joanna M. M. Howson, Michael Inouye, Martin Dichgans
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Stroke risk is influenced by genetic and lifestyle factors and previously a genomic risk score (GRS) for stroke was proposed, albeit with limited predictive power. Here, Abraham et al. develop a metaGRS that is composed of several stroke-related GRSs
Externí odkaz:
https://doaj.org/article/9a7c199b224d44308d309a590c357f39