Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Yonina R. Murciano‐Goroff"'
Autor:
Yonina R. Murciano-Goroff, Alison M. Schram, Ezra Y. Rosen, Helen Won, Yixiao Gong, Anne Marie Noronha, Yelena Y. Janjigian, Zsofia K. Stadler, Jason C. Chang, Soo-Ryum Yang, Diana Mandelker, Kenneth Offit, Michael F. Berger, Mark T. A. Donoghue, Chaitanya Bandlamudi, Alexander Drilon
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Mutations in BRCA1/2 are associated with a homologous recombination deficiency phenotype in BRCA-associated cancers. Reversion mutations can restore BRCA1/2 function and result in treatment resistance in these cancer-types. Here, the authors show tha
Externí odkaz:
https://doaj.org/article/c02201f79842463bb00562d13b866e18
Autor:
Emily S. Lebow, Narek Shaverdian, Jordan E. Eichholz, Leah B. Kratochvil, Megan McCune, Yonina R. Murciano-Goroff, Justin Jee, Juliana Eng, Jamie E. Chaft, Mark G. Kris, Ekaterina Kalashnikova, Jordan Feeney, Carly Bess Scalise, Sumedha Sudhaman, Charuta C. Palsuledesai, Meenakshi Malhotra, Michael Krainock, Himanshu Sethi, Alexey Aleshin, Minetta C. Liu, Annemarie F. Shepherd, Abraham J. Wu, Charles B. Simone, Daphna Y. Gelblum, Kaylie A. Johnson, Charles M. Rudin, Daniel R. Gomez, Pedram Razavi, Jorge S. Reis-Filho, James M. Isbell, Bob T. Li, Andreas Rimner
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundSensitive and reliable biomarkers for early detection of recurrence are needed to improve post-definitive radiation risk stratification, disease management, and outcomes for patients with unresectable early-stage or locally advanced non-sma
Externí odkaz:
https://doaj.org/article/3ba4f11343744c078451496fafdf072c
Autor:
Jonathan W. Goldman, Lynette M. Sholl, Sanja Dacic, Michael C. Fishbein, Yonina R. Murciano-Goroff, Ravi Rajaram, Sylwia Szymczak, Anna M. Szpurka, Bo H. Chao, Alexander Drilon
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
The LIBRETTO-001 trial demonstrated the activity of the selective rearrangement during transfection (RET) inhibitor selpercatinib in advanced RET fusion-positive non-small cell lung cancer (NSCLC) and resulted in the drug’s approval for this indica
Externí odkaz:
https://doaj.org/article/ff2adc6f3eaf4f15b17c63e038b1aa62
Autor:
Yonina R. Murciano-Goroff, Anne Marie McCarthy, Mirar N. Bristol, Susan M. Domchek, Peter W. Groeneveld, U. Nkiru Motanya, Katrina Armstrong
Publikováno v:
BMC Health Services Research, Vol 18, Iss 1, Pp 1-5 (2018)
Abstract Background Bundled payment programs play an increasingly important role in transforming reimbursement for oncologic care. We assessed determinants of oncologists’ willingness to participate in bundled payment programs for breast cancer. We
Externí odkaz:
https://doaj.org/article/a3f486778423441287c62b40b90a5f5d
Central Nervous System Disease in Patients With RET Fusion-Positive NSCLC Treated With Selpercatinib
Autor:
Yonina R. Murciano-Goroff, Christina J. Falcon, Sabrina T. Lin, Christina Chacko, Grace Grimaldi, Dazhi Liu, Clare Wilhelm, Alexia Iasonos, Alexander Drilon
Publikováno v:
Journal of Thoracic Oncology. 18:620-627
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::736ff189854008c0f61d689be93a6317
https://doi.org/10.1016/j.jtho.2023.01.008
https://doi.org/10.1016/j.jtho.2023.01.008
Autor:
Sushmita Gordhandas, Eric Rios-Doria, Karen A Cadoo, Amanda Catchings, Anna Maio, Yelena Kemel, Margaret Sheehan, Megha Ranganathan, Dina Green, Anjali Aryamvally, Angela G Arnold, Erin Salo-Mullen, Beryl Manning-Geist, Tiffany Sia, Pier Selenica, Arnaud Da Cruz Paula, Chad Vanderbilt, Maksym Misyura, Mario M Leitao, Jennifer J Mueller, Vicky Makker, Maria Rubinstein, Claire F Friedman, Qin Zhou, Alexia Iasonos, Alicia Latham, Maria I Carlo, Yonina R Murciano-Goroff, Marie Will, Michael F Walsh, Shirin Issa Bhaloo, Lora H Ellenson, Ozge Ceyhan-Birsoy, Michael F Berger, Mark E Robson, Nadeem Abu-Rustum, Carol Aghajanian, Kenneth Offit, Zsofia Stadler, Britta Weigelt, Diana L Mandelker, Ying L Liu
Publikováno v:
JNCI: Journal of the National Cancer Institute. 115:560-569
Background We sought to determine the prevalence of germline pathogenic variants (gPVs) in unselected patients with endometrial cancer (EC), define biallelic gPVs within tumors, and describe their associations with clinicopathologic features. Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec9f316b2b3f5be8abdd95005032897d
https://doi.org/10.1093/jnci/djad016
https://doi.org/10.1093/jnci/djad016
Autor:
Rona Yaeger, Riccardo Mezzadra, Jenna Sinopoli, Yu Bian, Michelangelo Marasco, Esther Kaplun, Yijun Gao, HuiYong Zhao, Arnaud Da Cruz Paula, Yingjie Zhu, Almudena Chaves Perez, Kalyani Chadalavada, Edison Tse, Sudhir Chowdhry, Sydney Bowker, Qing Chang, Besnik Qeriqi, Britta Weigelt, Gouri J. Nanjangud, Michael F. Berger, Hirak Der-Torossian, Kenna Anderes, Nicholas D. Socci, Jinru Shia, Gregory J. Riely, Yonina R. Murciano-Goroff, Bob T. Li, James G. Christensen, Jorge S. Reis-Filho, David B. Solit, Elisa de Stanchina, Scott W. Lowe, Neal Rosen, Sandra Misale
Publikováno v:
Cancer Discovery. :OF1-OF15
With the combination of KRASG12C and EGFR inhibitors, KRAS is becoming a druggable target in colorectal cancer. However, secondary resistance limits its efficacy. Using cell lines, patient-derived xenografts, and patient samples, we detected a hetero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3d232aac4bf14933900750105086f2b
https://doi.org/10.1158/2159-8290.cd-22-0405
https://doi.org/10.1158/2159-8290.cd-22-0405
Autor:
Jordi Rodón, Pauline Funchain, Theodore W Laetsch, Hendrik-Tobias Arkenau, Alice Hervieu, Christian F Singer, Yonina R Murciano-Goroff, Sant P Chawla, Kristin Anthony, Ikuo Yamamiya, Mei Liu, Abdel-Baset Halim, Karim A Benhadji, Osamu Takahashi, Suzette Delaloge
Publikováno v:
Future Oncology. 18:3377-3387
PTEN acts as a potent tumor suppressor within the PI3K/AKT/mTOR pathway. Germline mutations in the PTEN gene are a hallmark of PTEN hamartoma tumor syndrome, which includes Cowden syndrome, where they appear to elevate lifetime risk of cancer. Target
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34162849adde60d7fe1c74b81853dc25
https://doi.org/10.2217/fon-2022-0305
https://doi.org/10.2217/fon-2022-0305
Autor:
Sandra Misale, Neal Rosen, Scott W. Lowe, Elisa de Stanchina, David B. Solit, Jorge S. Reis-Filho, James G. Christensen, Bob T. Li, Yonina R. Murciano-Goroff, Gregory J. Riely, Jinru Shia, Nicholas D. Socci, Kenna Anderes, Hirak Der-Torossian, Michael F. Berger, Gouri J. Nanjangud, Britta Weigelt, Besnik Qeriqi, Qing Chang, Sydney Bowker, Sudhir Chowdhry, Edison Tse, Kalyani Chadalavada, Almudena Chaves Perez, Yingjie Zhu, Arnaud Da Cruz Paula, HuiYong Zhao, Yijun Gao, Esther Kaplun, Michelangelo Marasco, Yu Bian, Jenna Sinopoli, Riccardo Mezzadra, Rona Yaeger
With the combination of KRASG12C and EGFR inhibitors, KRAS is becoming a druggable target in colorectal cancer. However, secondary resistance limits its efficacy. Using cell lines, patient-derived xenografts, and patient samples, we detected a hetero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::321acf5988c203cec453f0f9392a6cbb
https://doi.org/10.1158/2159-8290.c.6549768
https://doi.org/10.1158/2159-8290.c.6549768
Autor:
Sandra Misale, Neal Rosen, Scott W. Lowe, Elisa de Stanchina, David B. Solit, Jorge S. Reis-Filho, James G. Christensen, Bob T. Li, Yonina R. Murciano-Goroff, Gregory J. Riely, Jinru Shia, Nicholas D. Socci, Kenna Anderes, Hirak Der-Torossian, Michael F. Berger, Gouri J. Nanjangud, Britta Weigelt, Besnik Qeriqi, Qing Chang, Sydney Bowker, Sudhir Chowdhry, Edison Tse, Kalyani Chadalavada, Almudena Chaves Perez, Yingjie Zhu, Arnaud Da Cruz Paula, HuiYong Zhao, Yijun Gao, Esther Kaplun, Michelangelo Marasco, Yu Bian, Jenna Sinopoli, Riccardo Mezzadra, Rona Yaeger
Generation of acquired resistance PDX model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b112c15ea1771670c6a5c8e6aa44819
https://doi.org/10.1158/2159-8290.22541925.v1
https://doi.org/10.1158/2159-8290.22541925.v1