Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Yoni, Haitin"'
Autor:
Bar Manori, Alisa Vaknin, Pavla Vaňková, Anat Nitzan, Ronen Zaidel-Bar, Petr Man, Moshe Giladi, Yoni Haitin
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Chloride Intracellular Channel (CLIC) family members uniquely transition between soluble and membrane-associated conformations. Despite decades of extensive functional and structural studies, CLICs’ function as ion channels remains debated
Externí odkaz:
https://doaj.org/article/ed70d145183b4b33a96ba0fb68a59de7
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-11 (2022)
Single-molecule microscopy and in situ cross-linking show that the conserved Tweety homolog (TTYH) proteins have an innate tetrameric organization at the cell membrane.
Externí odkaz:
https://doaj.org/article/69cd2820d12e46e287ed2c17c982f228
Autor:
Michal Lisnyansky Bar-El, Pavla Vaňková, Adva Yeheskel, Luba Simhaev, Hamutal Engel, Petr Man, Yoni Haitin, Moshe Giladi
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
The human cis-prenyltransferase (hcis-PT) complex synthesizes the precursor of the glycosyl carrier dolichol-phosphate and as such it is essential for protein N-glycosylation. The crystal structure of the complex reveals unusual tetrameric architectu
Externí odkaz:
https://doaj.org/article/ca8b3c5d53de4fce8b638a000a843aff
Autor:
Shai Kellner, Abeer Abbasi, Ido Carmi, Ronit Heinrich, Tali Garin-Shkolnik, Tova Hershkovitz, Moshe Giladi, Yoni Haitin, Katrine M Johannesen, Rikke Steensbjerre Møller, Shai Berlin
Publikováno v:
eLife, Vol 10 (2021)
The N-methyl-D-aspartate receptors (NMDARs; GluNRS) are glutamate receptors, commonly located at excitatory synapses. Mutations affecting receptor function often lead to devastating neurodevelopmental disorders. We have identified two toddlers with d
Externí odkaz:
https://doaj.org/article/b7a463d386444368ab21bae7d74b7c3b
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Abstract Chloride intracellular channels (CLICs) are a family of unique proteins, that were suggested to adopt both soluble and membrane-associated forms. Moreover, following this unusual metamorphic change, CLICs were shown to incorporate into membr
Externí odkaz:
https://doaj.org/article/d8813ac4fc1b461b81311090de4a4bce
Autor:
Moshe Giladi, Su Youn Lee, Yarden Ariely, Yotam Teldan, Rotem Granit, Roi Strulovich, Yoni Haitin, Ka Young Chung, Daniel Khananshvili
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Mammalian Na+/Ca2+ exchangers, NCX1 and NCX3, generate splice variants, whereas NCX2 does not. The CBD1 and CBD2 domains form a regulatory tandem (CBD12), where Ca2+ binding to CBD1 activates and Ca2+ binding to CBD2 (bearing the splicing se
Externí odkaz:
https://doaj.org/article/e36e68f88afb4f2581ecb244352f12a3
Autor:
Shira, Burg, Shir, Shapiro, Asher, Peretz, Elvira, Haimov, Boris, Redko, Adva, Yeheskel, Luba, Simhaev, Hamutal, Engel, Avi, Raveh, Ariel, Ben-Bassat, Michael, Murninkas, Rotem, Polak, Yoni, Haitin, Yoram, Etzion, Bernard, Attali
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(34)
The Ca
Autor:
Shira Burg, Shir Shapiro, Asher Peretz, Elvira Haimov, Boris Redko, Adva Yeheskel, Luba Simhaev, Hamutal Engel, Avi Raveh, Ariel Ben-Bassat, Michael Murninkas, Rotem Polak, Yoni Haitin, Yoram Etzion, Bernard Attali
Publikováno v:
Proceedings of the National Academy of Sciences. 119
The Ca 2+ -activated SK4 K + channel is gated by Ca 2+ –calmodulin (CaM) and is expressed in immune cells, brain, and heart. A cryoelectron microscopy (cryo-EM) structure of the human SK4 K + channel recently revealed four CaM molecules per channel
Autor:
Michal Lisnyansky Bar-El, Su Youn Lee, Ah Young Ki, Noa Kapelushnik, Anat Loewenstein, Ka Young Chung, Dina Schneidman-Duhovny, Moshe Giladi, Hadas Newman, Yoni Haitin
Publikováno v:
Biomolecules, Vol 9, Iss 11, p 660 (2019)
Dehydrodolichyl diphosphate synthase (DHDDS) is the catalytic subunit of the heteromeric human cis-prenyltransferase complex, synthesizing the glycosyl carrier precursor for N-linked protein glycosylation. Consistent with the important role of N-glyc
Externí odkaz:
https://doaj.org/article/78460d588c3749d3a14e6bd27c96b83c
Autor:
Omri Shelef, Sara Gutkin, Daniel Feder, Ariel Ben-Bassat, Michal Mandelboim, Yoni Haitin, Nir Ben-Tal, Eran Bacharach, Doron Shabat
Publikováno v:
Chemical science. 13(42)
Influenza A virus is the most virulent influenza subtype and is associated with large-scale global pandemics characterized by high levels of morbidity and mortality. Developing simple and sensitive molecular methods for detecting influenza viruses is